(a.) Moving or extending from a higher to a lower place; tending toward the earth or its center, or toward a lower level; declivous.
(a.) Descending from a head, origin, or source; as, a downward line of descent.
(a.) Tending to a lower condition or state; depressed; dejected; as, downward thoughts.
Example Sentences:
(1) Over a period of 9 months a 12-year-old girl spontaneously developed a palpable cystic tumor in the upper eye lid which led to an indentation and downward displacement of the globe.
(2) Cerebral angiogram displayed a contralateral shift and an unrolling of the anterior cerebral artery, a lateral stretch of middle cerebral artery, a downward stretch of anterior choroidal artery and a tumor stain fed by the Heubner artery.
(3) In this study downward gaze was more severely disturbed than upward gaze.
(4) Business rates: pressure grows for total rethink on controversial tax Read more Meanwhile the downwards press on aggregate council funding is unremitting.
(5) downward occupational and downward social drift, premature retirement and achievement of the expected social development.
(6) In all the RIAs, the dose-response curves obtained on delayed addition by 24 to 48 h of labeled antigens (curves B), were shifted downwards and to the left of those obtained on simultaneous addition of the reagents (curves A), resulting in improved sensitivity of the assay.
(7) A downward protraction force produced relatively uniform stress distributions, indicating the importance of the force direction in determining the stress distributions from various orthopedic forces.
(8) Pregnant women showed an overall downward trend in susceptibility to rubella (from 4.2% at the beginning of 1984 to 3.0% at the end of 1986), and a similar decline was seen in the two other categories.
(9) Put simply, there would have to be evidence that ultra-low oil prices are having only a temporary downward impact on inflation and have helped disguise upward pressure on wages caused by falling unemployment.
(10) With systole there is downward (caudal) flow of CSF in the aqueduct of Sylvius, the foramen of Magendie, the basal cisterns and the dorsal and ventral subarachnoid spaces while during diastole, upward (cranial) flow of CSF in these same structures is seen.
(11) The company's value lies in its FM licence for London, with the audience for its national AM licence spiralling downwards in recent years.
(12) Although the muscles of untreated children also showed shifts of mean frequency to lower frequency values as a function of time, there was a greater downward shift of mean frequency in those treated with functional appliances.
(13) Assuming no future environmental or lifestyle changes, the upward trend in age-adjusted mortality rates, which averaged 2 to 3% per annum since 1950, is projected to discontinue and bend downward by the second decade of the 21st century.
(14) That does not mean that natural ice variability cannot bring it back again, but the trend, we think, will be downward."
(15) These findings suggest that the response to a downward shift of frequency with an amplitude increase results from new activation due to an apical extension of the envelope of the traveling wave and thus represents the activity in a restricted area of the basilar membrane.
(16) The technique consists of wide undermining of supranasal and paranasal skin, use of composite auricular grafts from the ear to lengthen the upper lateral cartilages, use of a chondromucosal septal flap for lengthening the septum, and postoperative downward taping to assure adequate stretching of dorsal skin for the first-stage procedure.
(17) The virus initially appeared within certain keratinocytes, sometimes surrounded by keratinocytes whose surfaces were also positive for the antigens, in the lower epidermal layers including the hair follicles, and then extended upward to the entire epidermis and downward to the sebaceous glands 1-2 days later, when no macroscopic skin lesion was seen.
(18) Erythrocyte sedimentation highly increased leucocyte retention in vertical columns with a downward flow, whereas in slightly tilted columns with an upward flow, the retention was reduced.
(19) Chorismate mutase was also inhibited by prephenate, which caused downward double-reciprocal plots and a Hill coefficient of n = 0.7, evidence for negative cooperativity.
(20) The Saudis and other Gulf states still support rebel fighting formations – as much because of inertia and hostility to Iran as anything else – but western backing is on a downward trajectory as concerns mount about the risks of blowback from al-Qaida-linked groups.
Level
Definition:
(n.) A line or surface to which, at every point, a vertical or plumb line is perpendicular; a line or surface which is everywhere parallel to the surface of still water; -- this is the true level, and is a curve or surface in which all points are equally distant from the center of the earth, or rather would be so if the earth were an exact sphere.
(n.) A horizontal line or plane; that is, a straight line or a plane which is tangent to a true level at a given point and hence parallel to the horizon at that point; -- this is the apparent level at the given point.
(n.) An approximately horizontal line or surface at a certain degree of altitude, or distance from the center of the earth; as, to climb from the level of the coast to the level of the plateau and then descend to the level of the valley or of the sea.
(n.) Hence, figuratively, a certain position, rank, standard, degree, quality, character, etc., conceived of as in one of several planes of different elevation.
(n.) A uniform or average height; a normal plane or altitude; a condition conformable to natural law or which will secure a level surface; as, moving fluids seek a level.
(n.) An instrument by which to find a horizontal line, or adjust something with reference to a horizontal line.
(n.) A measurement of the difference of altitude of two points, by means of a level; as, to take a level.
(n.) A horizontal passage, drift, or adit, in a mine.
(a.) Even; flat; having no part higher than another; having, or conforming to, the curvature which belongs to the undisturbed liquid parts of the earth's surface; as, a level field; level ground; the level surface of a pond or lake.
(a.) Coinciding or parallel with the plane of the horizon; horizontal; as, the telescope is now level.
(a.) Even with anything else; of the same height; on the same line or plane; on the same footing; of equal importance; -- followed by with, sometimes by to.
(a.) Straightforward; direct; clear; open.
(a.) Well balanced; even; just; steady; impartial; as, a level head; a level understanding. [Colloq.]
(a.) Of even tone; without rising or falling inflection.
(v. t.) To make level; to make horizontal; to bring to the condition of a level line or surface; hence, to make flat or even; as, to level a road, a walk, or a garden.
(v. t.) To bring to a lower level; to overthrow; to topple down; to reduce to a flat surface; to lower.
(v. t.) To bring to a horizontal position, as a gun; hence, to point in taking aim; to aim; to direct.
(v. t.) Figuratively, to bring to a common level or plane, in respect of rank, condition, character, privilege, etc.; as, to level all the ranks and conditions of men.
(v. t.) To adjust or adapt to a certain level; as, to level remarks to the capacity of children.
(v. i.) To be level; to be on a level with, or on an equality with, something; hence, to accord; to agree; to suit.
(v. i.) To aim a gun, spear, etc., horizontally; hence, to aim or point a weapon in direct line with the mark; fig., to direct the eye, mind, or effort, directly to an object.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(3) Multiple stored energy levels were randomly tested and the percent successful defibrillation was plotted against the stored energy, and the raw data were fit by logistic regression.
(4) Serum levels of both dihydralazine and metabolites were very low and particularly below the detection limit.
(5) Carbon dioxide (CO2) levels, volumes, and temperatures of expired gas were measured from the tracheal and esophageal tubes.
(6) Since fingernail creatinine (Ncr) reflects serum creatinine (Scr) at the time of nail formation, it has been suggested that Ncr level might represent that of Scr around 4 months previously.
(7) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(8) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(9) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(10) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
(11) On the other hand, the LAP level, identical in preterms and SDB, is lower than in full-term infants but higher than in adults.
(12) BL6 mouse melanoma cells lack detectable H-2Kb and had low levels of expression of H-2Db Ag.
(13) Together these results suggest that IVC may operate as a selective activator of calpain both in the cytosol and at the membrane level; in the latter case in synergism with the activation induced by association of the proteinase to the cell membrane.
(14) Participants (n=165) entering a week-long outpatient education program completed a protocol measuring self-care patterns, glycosylated hemoglobin levels, and emotional well-being.
(15) Measurement of the intraspinal monoamine level revealed a decrease in the intraspinal norepinephrine level in the treated animals.
(16) The level of gadd45 mRNA increased rapidly after X rays at doses as low as 2 Gy.
(17) Irrespective of the type of arthropathy, synovial fluid dialysable hydroxyproline levels correlate with urinary hydroxyproline excretion.
(18) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(19) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(20) This new observation offers good possibilities to study the metabolism of tryptophan at the cellular level.