(a.) Moving or extending from a higher to a lower place; tending toward the earth or its center, or toward a lower level; declivous.
(a.) Descending from a head, origin, or source; as, a downward line of descent.
(a.) Tending to a lower condition or state; depressed; dejected; as, downward thoughts.
Example Sentences:
(1) Over a period of 9 months a 12-year-old girl spontaneously developed a palpable cystic tumor in the upper eye lid which led to an indentation and downward displacement of the globe.
(2) Cerebral angiogram displayed a contralateral shift and an unrolling of the anterior cerebral artery, a lateral stretch of middle cerebral artery, a downward stretch of anterior choroidal artery and a tumor stain fed by the Heubner artery.
(3) In this study downward gaze was more severely disturbed than upward gaze.
(4) Business rates: pressure grows for total rethink on controversial tax Read more Meanwhile the downwards press on aggregate council funding is unremitting.
(5) downward occupational and downward social drift, premature retirement and achievement of the expected social development.
(6) In all the RIAs, the dose-response curves obtained on delayed addition by 24 to 48 h of labeled antigens (curves B), were shifted downwards and to the left of those obtained on simultaneous addition of the reagents (curves A), resulting in improved sensitivity of the assay.
(7) A downward protraction force produced relatively uniform stress distributions, indicating the importance of the force direction in determining the stress distributions from various orthopedic forces.
(8) Pregnant women showed an overall downward trend in susceptibility to rubella (from 4.2% at the beginning of 1984 to 3.0% at the end of 1986), and a similar decline was seen in the two other categories.
(9) Put simply, there would have to be evidence that ultra-low oil prices are having only a temporary downward impact on inflation and have helped disguise upward pressure on wages caused by falling unemployment.
(10) With systole there is downward (caudal) flow of CSF in the aqueduct of Sylvius, the foramen of Magendie, the basal cisterns and the dorsal and ventral subarachnoid spaces while during diastole, upward (cranial) flow of CSF in these same structures is seen.
(11) The company's value lies in its FM licence for London, with the audience for its national AM licence spiralling downwards in recent years.
(12) Although the muscles of untreated children also showed shifts of mean frequency to lower frequency values as a function of time, there was a greater downward shift of mean frequency in those treated with functional appliances.
(13) Assuming no future environmental or lifestyle changes, the upward trend in age-adjusted mortality rates, which averaged 2 to 3% per annum since 1950, is projected to discontinue and bend downward by the second decade of the 21st century.
(14) That does not mean that natural ice variability cannot bring it back again, but the trend, we think, will be downward."
(15) These findings suggest that the response to a downward shift of frequency with an amplitude increase results from new activation due to an apical extension of the envelope of the traveling wave and thus represents the activity in a restricted area of the basilar membrane.
(16) The technique consists of wide undermining of supranasal and paranasal skin, use of composite auricular grafts from the ear to lengthen the upper lateral cartilages, use of a chondromucosal septal flap for lengthening the septum, and postoperative downward taping to assure adequate stretching of dorsal skin for the first-stage procedure.
(17) The virus initially appeared within certain keratinocytes, sometimes surrounded by keratinocytes whose surfaces were also positive for the antigens, in the lower epidermal layers including the hair follicles, and then extended upward to the entire epidermis and downward to the sebaceous glands 1-2 days later, when no macroscopic skin lesion was seen.
(18) Erythrocyte sedimentation highly increased leucocyte retention in vertical columns with a downward flow, whereas in slightly tilted columns with an upward flow, the retention was reduced.
(19) Chorismate mutase was also inhibited by prephenate, which caused downward double-reciprocal plots and a Hill coefficient of n = 0.7, evidence for negative cooperativity.
(20) The Saudis and other Gulf states still support rebel fighting formations – as much because of inertia and hostility to Iran as anything else – but western backing is on a downward trajectory as concerns mount about the risks of blowback from al-Qaida-linked groups.
Lower
Definition:
(a.) Compar. of Low, a.
(a.) To let descend by its own weight, as something suspended; to let down; as, to lower a bucket into a well; to lower a sail or a boat; sometimes, to pull down; as, to lower a flag.
(a.) To reduce the height of; as, to lower a fence or wall; to lower a chimney or turret.
(a.) To depress as to direction; as, to lower the aim of a gun; to make less elevated as to object; as, to lower one's ambition, aspirations, or hopes.
(a.) To reduce the degree, intensity, strength, etc., of; as, to lower the temperature of anything; to lower one's vitality; to lower distilled liquors.
(a.) To bring down; to humble; as, to lower one's pride.
(a.) To reduce in value, amount, etc. ; as, to lower the price of goods, the rate of interest, etc.
(v. i.) To fall; to sink; to grow less; to diminish; to decrease; as, the river lowered as rapidly as it rose.
(v. i.) To be dark, gloomy, and threatening, as clouds; to be covered with dark and threatening clouds, as the sky; to show threatening signs of approach, as a tempest.
(v. i.) To frown; to look sullen.
(n.) Cloudiness; gloominess.
(n.) A frowning; sullenness.
Example Sentences:
(1) These factors might account for the lower systemic bioavailability of these compounds.
(2) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(3) In this study of ten consecutive patients sustaining molten metal injuries to the lower extremity who were treated with excision and grafting, treatment with compression Unna paste boot was compared with that with conventional dressing.
(4) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
(5) Homozygotes have sparse greasy fur and lower viability and fertility than normal littermates.
(6) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
(7) On the other hand, the LAP level, identical in preterms and SDB, is lower than in full-term infants but higher than in adults.
(8) It is suggested that the Japanese may have lower trabecular bone mineral density than Caucasians but may also have a lower threshold for fracture of the vertebrae.
(9) Spontaneous locomotor activity was lower in naloxone-infused rats on day 3 only.
(10) After 55 days of unrestricted food availability the body weight of the neonatally deprived rats was approximately 15% lower than that of the controls.
(11) There is no evidence that health-maintenance organizations reduce admissions in discretionary or "unnecessary" categories; instead, the data suggest lower admission rates across the board.
(12) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(13) [Ca2+]i exhibited a sigmoidal dependence on [Na+]o. Mg2+, a competitive inhibitor of Na2+-Ca2+ antiport in these cells, antagonized the increase in [Ca2+]i produced by lowering [Na+]o.
(14) Side effect incidence in patients treated with the paracetamol-sobrerol combination (3.7%) was significantly lower than that observed in subjects treated with paracetamol (6.1% - P less than 0.01), salicylics (25.1% - P less than 0.001), pyrazolics (12.6% - P less than 0.001), propionics (20.3%, P less than 0.001) or other antipyretics (17.9% - P less than 0.001).
(15) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(16) Diltiazem monotherapy effectively lowered blood pressure in 60% of patients at 8 weeks.
(17) Thus, our study confirmed that male subjects with a history of testicular maldescent have an increased risk for testis cancer, although the magnitude of this risk was lower than suggested previously.
(18) Anesthetized sheep (n = 6) previously prepared with a lung lymph fistula underwent 2 hr of tourniquet ischemia of both lower limbs.
(19) Nicardipine lowered systolic and diastolic blood pressure to normal, plasma aldosterone was reduced and serum potassium levels were increased.
(20) The overall recoveries of activated ER following chromatography on DEAE-cellulose were significantly lower than the recoveries of the nonactivated ER, 71 and 85%, respectively.