(a.) Acting rapidly and violently; efficacious; powerful; -- opposed to bland; as, drastic purgatives.
(n.) A violent purgative. See Cathartic.
Example Sentences:
(1) During the first three weeks of adaptation drastic changes in the parameter were seen.
(2) The differentiation between the various modes of involvement is essential as some of them may be confused with recurrence and the clinician might resort to unnecessary drastic measures like enucleation.
(3) Survival rates depend on age: 5 years survival rate of patients up to 65 years was 8,1% (59 of 729) and fell drastically in patients of 65+ years (28 of 1109 = 2,5%).
(4) While visitors amble freely around the newly refurbished inside – the Pierhead is sure and steadfast in its role outside as the drastic red building, emblazoning the landscape of Cardiff Bay in all its regal beauty.
(5) Optic chiasm transection drastically diminished this ability, callosal section had little effect and combined lesions of these two structures abolished stereoperception.
(6) The observed drastic interstrain differences in dopamine receptor sensitivity demonstrate the essential role of genotype in the effects of dopaminergic drugs.
(7) Treatment of Xenopus laevis membranes with the 2',3'-dialdehyde of GTP (dial GTP) drastically inhibits their adenylyl cyclase activity.
(8) Ivermectin treatment of all cattle on a badly infected farm failed to interrupt the transmission of P. bovicola, even though ovipositional blood spots were drastically reduced in numbers for an entire summer season following treatment.
(9) The number of DAB positive organelles per surface area decreased steadily with culture age, and significantly on day 2 (p less than 0.01) to become drastically low on day 5 and negligible on day 7.
(10) However, treatment of intact worms drastically affected the integrity of the membrane.
(11) Treatment with glucocorticosteroids has drastically improved the prognosis.
(12) Only a drastic osmotic shock in distillated water as a mean to disrupt mitochondrial membrane was found to strongly increase the actual rate of the rotenone-sensitive activity.
(13) Such a drastic measure in an impossibly short timeframe would deprive generations of refugees of any choices for their future,” said Charles Gaudry, MSF’s head of mission in Kenya.
(14) In the deforming osteo-arthrosis (150 observations) in the synovial sheath there were usually noted drastic sclerosis and atrophy of organ-specific structures, impairmement of the production of the synovial fluid, and dystrophic falling into fibers of the articular cartilage with intensive proliferation of the cartilage cells.
(15) This was primarily due to the drastic decrease with age in excretion of bis-digitoxoside.
(16) The velocity of darkness adaptation was drastically changed in patients with chronic alcoholism but it was also reversible.
(17) The combined effects lead to a drastic antimutagenic effect, the molecular mechanism of which is given by these changes in mutagen-metabolizing enzymes.
(18) Decreasing the water concentration in the reaction medium by adding methanol at 0 degrees C drastically reduces the rate of racemization without affecting the rate of transamination.
(19) The factor production during a certain period of the development of lines is drastically increased by radiation.
(20) Excretion of zinc and especially of silicon through the kidneys and intestine drastically grew on the day of the contest.
Moderate
Definition:
(a.) Kept within due bounds; observing reasonable limits; not excessive, extreme, violent, or rigorous; limited; restrained
(a.) Limited in quantity; sparing; temperate; frugal; as, moderate in eating or drinking; a moderate table.
(a.) Limited in degree of activity, energy, or excitement; reasonable; calm; slow; as, moderate language; moderate endeavors.
(a.) Not extreme in opinion, in partisanship, and the like; as, a moderate Calvinist.
(a.) Not violent or rigorous; temperate; mild; gentle; as, a moderate winter.
(a.) Limited as to degree of progress; as, to travel at moderate speed.
(a.) Limited as to the degree in which a quality, principle, or faculty appears; as, an infusion of moderate strength; a man of moderate abilities.
(a.) Limited in scope or effects; as, a reformation of a moderate kind.
(n.) One of a party in the Church of Scotland in the 18th century, and part of the 19th, professing moderation in matters of church government, in discipline, and in doctrine.
(v. t.) To restrain from excess of any kind; to reduce from a state of violence, intensity, or excess; to keep within bounds; to make temperate; to lessen; to allay; to repress; to temper; to qualify; as, to moderate rage, action, desires, etc.; to moderate heat or wind.
(v. t.) To preside over, direct, or regulate, as a public meeting; as, to moderate a synod.
(v. i.) To become less violent, severe, rigorous, or intense; as, the wind has moderated.
(v. i.) To preside as a moderator.
Example Sentences:
(1) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(2) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(3) In the surface epithelial cells, the basolateral cell surface showed moderate enzymatic activity.
(4) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(5) Systemic corticosteroids (i.e., prednisone, prednisolone or methylprednisolone) have improved the survival rate of patients with moderate and severe ulcerative colitis.
(6) We report the results of a double-blind, placebo-controlled trial of acitretin (Soriatane) in 15 patients with moderate to severe psoriasis.
(7) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(8) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(9) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(10) The radius is estimated to be around 1.7 nm, which shows a moderate degree of hydration.
(11) The deep cerebellar nuclei were moderately labeled at birth and gradually decreased in density thereafter.
(12) The epithelium of Brunner's gland stained intensely with Ricinus communis agglutinin-I (RCA-I), succinylated-WGA (S-WGA) and wheat-germ agglutinin (WGA), moderately with Bandeirea simplicifolia agglutinin-I (BS-I), Concanavalia ensiformis agglutinin (Con A) peanut agglutinin (PNA) and Ulex europaeus agglutinin-I (UEA-I) and occasionally with Dolichos biflorus agglutinin (DBA), Lens culinaris agglutinin (LCA) and soybean agglutinin (SBA).
(13) 2-(4'-Isobutylphenyl)propionic acid, ibuprofen, is an antiinflammatory agent which possesses moderate platelet aggregation inhibitory activity.
(14) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(15) The remaining 33 sera (13.3 per cent) were classified as low, moderate or strong positives.
(16) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(17) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(18) C. tropicalis was grown in a medium containing Brij 35, resulting in the induction of a moderate number of medium-sized peroxisomes.
(19) Data from 579 medical students from the classes of 1979-80 through 1983-84 attending a midwestern medical college were analyzed via moderated multiple regression.
(20) Altering the time of PMA exposure demonstrated that PMA inhibited chondrocyte phenotypic expression, rather than cell commitment: early (0-48 h) exposure to PMA (during chondrocytic commitment in vitro) had little inhibitory effect on the staining index, whereas, exposure from 49-96 h (presumably post-commitment) and 0-96 h had moderate and strong inhibitory effects, respectively, on cartilage synthesis.