(a.) Acting rapidly and violently; efficacious; powerful; -- opposed to bland; as, drastic purgatives.
(n.) A violent purgative. See Cathartic.
Example Sentences:
(1) During the first three weeks of adaptation drastic changes in the parameter were seen.
(2) The differentiation between the various modes of involvement is essential as some of them may be confused with recurrence and the clinician might resort to unnecessary drastic measures like enucleation.
(3) Survival rates depend on age: 5 years survival rate of patients up to 65 years was 8,1% (59 of 729) and fell drastically in patients of 65+ years (28 of 1109 = 2,5%).
(4) While visitors amble freely around the newly refurbished inside – the Pierhead is sure and steadfast in its role outside as the drastic red building, emblazoning the landscape of Cardiff Bay in all its regal beauty.
(5) Optic chiasm transection drastically diminished this ability, callosal section had little effect and combined lesions of these two structures abolished stereoperception.
(6) The observed drastic interstrain differences in dopamine receptor sensitivity demonstrate the essential role of genotype in the effects of dopaminergic drugs.
(7) Treatment of Xenopus laevis membranes with the 2',3'-dialdehyde of GTP (dial GTP) drastically inhibits their adenylyl cyclase activity.
(8) Ivermectin treatment of all cattle on a badly infected farm failed to interrupt the transmission of P. bovicola, even though ovipositional blood spots were drastically reduced in numbers for an entire summer season following treatment.
(9) The number of DAB positive organelles per surface area decreased steadily with culture age, and significantly on day 2 (p less than 0.01) to become drastically low on day 5 and negligible on day 7.
(10) However, treatment of intact worms drastically affected the integrity of the membrane.
(11) Treatment with glucocorticosteroids has drastically improved the prognosis.
(12) Only a drastic osmotic shock in distillated water as a mean to disrupt mitochondrial membrane was found to strongly increase the actual rate of the rotenone-sensitive activity.
(13) Such a drastic measure in an impossibly short timeframe would deprive generations of refugees of any choices for their future,” said Charles Gaudry, MSF’s head of mission in Kenya.
(14) In the deforming osteo-arthrosis (150 observations) in the synovial sheath there were usually noted drastic sclerosis and atrophy of organ-specific structures, impairmement of the production of the synovial fluid, and dystrophic falling into fibers of the articular cartilage with intensive proliferation of the cartilage cells.
(15) This was primarily due to the drastic decrease with age in excretion of bis-digitoxoside.
(16) The velocity of darkness adaptation was drastically changed in patients with chronic alcoholism but it was also reversible.
(17) The combined effects lead to a drastic antimutagenic effect, the molecular mechanism of which is given by these changes in mutagen-metabolizing enzymes.
(18) Decreasing the water concentration in the reaction medium by adding methanol at 0 degrees C drastically reduces the rate of racemization without affecting the rate of transamination.
(19) The factor production during a certain period of the development of lines is drastically increased by radiation.
(20) Excretion of zinc and especially of silicon through the kidneys and intestine drastically grew on the day of the contest.
Rigorous
Definition:
(a.) Manifesting, exercising, or favoring rigor; allowing no abatement or mitigation; scrupulously accurate; exact; strict; severe; relentless; as, a rigorous officer of justice; a rigorous execution of law; a rigorous definition or demonstration.
(a.) Severe; intense; inclement; as, a rigorous winter.
(a.) Violent.
Example Sentences:
(1) He added: "There is a rigorous review process of applications submitted by the executive branch, spearheaded initially by five judicial branch lawyers who are national security experts and then by the judges, to ensure that the court's authorizations comport with what the applicable statutes authorize."
(2) Upon depletion of ATP in contraction, the P2 intensity reverted to the original rigor level, accompanied by development of rigor tension.
(3) which suggest that ~60-90% of the cross-bridges attached in rigor are attached in relaxed fibers at an ionic strength of 20 mM and ~2-10% of this number of cross-bridges are attached in a relaxed fiber at an ionic strength of 170 mM.
(4) The symptoms were successfully controlled by rigorous dietary measures.
(5) Rigorously designed clinical trials have demonstrated the efficacy and safety of fluoxetine in adults with major depressive disorder and obsessive-compulsive disorder (OCD) but not in patients below 18 years old.
(6) Unambiguous mapping and rigorous determination of the nature of the initiation triplet for IF2 beta, the smaller form of IF2, is critical for future mutagenesis of this codon, required for investigating the biological importance of both IF2 alpha and IF2 beta.
(7) The identification of the cDNA for an A2b-adenosine receptor will allow more rigorous characterization of its anatomical distribution and functional properties.
(8) Meanwhile, we need to show that the recent changes to how we work with the BBC Executive are allowing us to be more focused, more rigorous and more transparent in the work that we do, so that licence fee payers can get a better BBC.
(9) A village will be subject to rigorous evaluations in order to demonstrate sustainability and scalability, and that aid developed with an exit strategy can actually work.
(10) We therefore conclude that in postrigor muscles, paratropomyosin is released from the A-I junction region following the increase in the sarcoplasmic calcium ion concentration to 10(-4) M, and then binds to thin filaments, which results in weakening of rigor linkages formed between actin and myosin.
(11) New observations include: (1) In 15 nm cross sections that show single 14.5 nm levels: (a) The flared X structure characteristic of rigor is replaced by a straight-X figure in which the crossbridge density is aligned along the myosin-actin plane, rather than skewed across it as in rigor.
(12) Ferguson’s influence at Old Trafford has clearly waned since the Moyes appointment but, notably, there is no admission on his part that he chose the wrong man, insisting that the club followed a rigorous and methodical selection process.
(13) After a three-month period of rigorous training, two PAs were assigned to the ICU.
(14) Over the last few days a former member of parliament's intelligence and security committee, Lord King, a former director of GCHQ, Sir David Omand, and a former director general of MI5, Dame Stella Rimington, have questioned whether the agencies need to be more transparent and accept more rigorous scrutiny of their work.
(15) Even when carried out rigorously, culling does very little to help.
(16) Because the rigor of the present day "scientific method" demands clearcut and reproducible results and investigations require predictable performance of the parasite in an evenly maintained host that is in a highly constrained environment, we should not wonder why we cannot produce the events of nature.
(17) The best definition of osteoarthritis is anatomical, but to be rigorous must include the biochemical characteristics of osteoarthritis cartilage.
(18) "We remain committed to sourcing merchandise that is produced responsibly by suppliers that adhere to Walmart's rigorous Standards for Suppliers code of conduct."
(19) Edelman has a rigorous in-house carbon accounting system.
(20) Material, obtained by a rigorous three-stage sampling procedure from five normal rat livers, is systematically subjected to this analysis at four levels of magnification.