(a.) Acting rapidly and violently; efficacious; powerful; -- opposed to bland; as, drastic purgatives.
(n.) A violent purgative. See Cathartic.
Example Sentences:
(1) During the first three weeks of adaptation drastic changes in the parameter were seen.
(2) The differentiation between the various modes of involvement is essential as some of them may be confused with recurrence and the clinician might resort to unnecessary drastic measures like enucleation.
(3) Survival rates depend on age: 5 years survival rate of patients up to 65 years was 8,1% (59 of 729) and fell drastically in patients of 65+ years (28 of 1109 = 2,5%).
(4) While visitors amble freely around the newly refurbished inside – the Pierhead is sure and steadfast in its role outside as the drastic red building, emblazoning the landscape of Cardiff Bay in all its regal beauty.
(5) Optic chiasm transection drastically diminished this ability, callosal section had little effect and combined lesions of these two structures abolished stereoperception.
(6) The observed drastic interstrain differences in dopamine receptor sensitivity demonstrate the essential role of genotype in the effects of dopaminergic drugs.
(7) Treatment of Xenopus laevis membranes with the 2',3'-dialdehyde of GTP (dial GTP) drastically inhibits their adenylyl cyclase activity.
(8) Ivermectin treatment of all cattle on a badly infected farm failed to interrupt the transmission of P. bovicola, even though ovipositional blood spots were drastically reduced in numbers for an entire summer season following treatment.
(9) The number of DAB positive organelles per surface area decreased steadily with culture age, and significantly on day 2 (p less than 0.01) to become drastically low on day 5 and negligible on day 7.
(10) However, treatment of intact worms drastically affected the integrity of the membrane.
(11) Treatment with glucocorticosteroids has drastically improved the prognosis.
(12) Only a drastic osmotic shock in distillated water as a mean to disrupt mitochondrial membrane was found to strongly increase the actual rate of the rotenone-sensitive activity.
(13) Such a drastic measure in an impossibly short timeframe would deprive generations of refugees of any choices for their future,” said Charles Gaudry, MSF’s head of mission in Kenya.
(14) In the deforming osteo-arthrosis (150 observations) in the synovial sheath there were usually noted drastic sclerosis and atrophy of organ-specific structures, impairmement of the production of the synovial fluid, and dystrophic falling into fibers of the articular cartilage with intensive proliferation of the cartilage cells.
(15) This was primarily due to the drastic decrease with age in excretion of bis-digitoxoside.
(16) The velocity of darkness adaptation was drastically changed in patients with chronic alcoholism but it was also reversible.
(17) The combined effects lead to a drastic antimutagenic effect, the molecular mechanism of which is given by these changes in mutagen-metabolizing enzymes.
(18) Decreasing the water concentration in the reaction medium by adding methanol at 0 degrees C drastically reduces the rate of racemization without affecting the rate of transamination.
(19) The factor production during a certain period of the development of lines is drastically increased by radiation.
(20) Excretion of zinc and especially of silicon through the kidneys and intestine drastically grew on the day of the contest.
Serious
Definition:
(a.) Grave in manner or disposition; earnest; thoughtful; solemn; not light, gay, or volatile.
(a.) Really intending what is said; being in earnest; not jesting or deceiving.
(a.) Important; weighty; not trifling; grave.
(a.) Hence, giving rise to apprehension; attended with danger; as, a serious injury.
Example Sentences:
(1) This should not be a serious limitation to the application of the RIA in the detection of venous thrombosis.
(2) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(3) "There is a serious risk that a deal will be agreed between rich countries and tax havens that would leave poor countries out in the cold.
(4) Confidence is the major prerequisite for a doctor to be able to help his seriously ill patient.
(5) No report can be taken seriously if its authors weren’t even in Yemen to conduct investigations.” The UN team was not given permission to enter the country.
(6) The decline in the frequency of serious complications was primarily due to a decrease in the proportion of patients with open fractures treated with plate osteosynthesis from nearly 50% to 19%.
(7) Vancomycin is the antibiotic of choice for serious MRSA infections; PRPs and cephalosporins generally are not effective.
(8) An age- and education-matched group of women with no family history of FXS was asked to predict the seriousness of problems they might encounter were they to bear a child with a handicapping condition.
(9) The most serious complications following operative treatment are retained bile duct calculi (2.8%), wound infection and biliary fistulae.
(10) Guardian Australia reported last week that morale at the national laboratory had fallen dramatically, with one in three staff “seriously considering” leaving their jobs in the wake of the cuts.
(11) In case of biliary and pancreatic duct obstruction with pure pancreatic reflux, both oedema and inflammatory infiltrations were evident, whereas, in the presence of biliary reflux too, more serious histological features were detected.
(12) Autopsy revealed serious somatic diseases (stenosis of the ileum in two cases and brain tumor in one); their symptoms had been largely overlapped by those of anorexia nervosa.
(13) The above treatment is tolerated well and no serious side effects have been observed.
(14) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(15) Earlier recognition of foul-smelling mucoid discharge on the IUD tail, or abnormal bleeding, or both, as a sign of early pelvic infection, followed by removal of the IUD and institution of appropriate antibiotic therapy, might prevent the more serious sequelae of pelvic inflammation.
(16) Left ventricular rupture is a serious complication of mitral valve replacement.
(17) Other serious complications were reservoir perforation during catheterisation in 3 and development of stones in the reservoir in 2 patients.
(18) For application to mammalian cells, however, two serious problems require resolution: (1), correction of TPP+ binding to intracellular constituents and (2), estimation of the considerable TPP+ accumulation in mitochondria.
(19) At least 1 episode of serious infection occurred in 34 of the 60 adult patients and 25 of the 30 children.
(20) These high Danish rates seem to reflect the true prevalence and incidence in the less serious types of progressive muscular dystrophy, probably because the Danish health system with free medical care and easy access to specialized hospital departments makes it possible to identify all cases of progressive muscular dystrophy.