(n.) Corrupt or defiling matter contained in a liquid, or precipitated from it; refuse; feculence; lees; grounds; sediment; hence, the vilest and most worthless part of anything; as, the dregs of society.
Example Sentences:
(1) Receptors known as DREG adhesion molecules on human neutrophils and monocytes provide for homing of these phagocytic leukocytes to sites of inflammation.
(2) Finally, all five DREG mAbs specifically stain COS cells transfected with LAM-1 cDNA, a putative human homologue of mouse MEL-14 antigen.
(3) Perhaps set smaller goals to begin with, for instance "Don't drink the dregs of strangers' drinks" or "No drinking on your own in the morning in a toilet cubicle at work", and see where you go from there.
(4) We studied its expression on eosinophils using flow cytometry and the MAb Dreg-56 and Leu-8.
(5) While the fourth seeded Bulls’ 35-29 record is something of a mirage, as they have faced the dregs of the Eastern Conference, that doesn’t take away from the fact this team was expected to be one of those dregs after Rose injured himself and Deng was traded.
(6) Accumulation of DREG-negative monocytes in association with sepsis may be sufficient to impair their recruitment to inflammatory sites and limit their contribution to host defense against infection and tissue repair.
(7) From the depraved dregs of humanity; the glorious blossoming of hope, a tangible act of togetherness; the salvation of pop.
(8) "If you think that in this country another person can be found who would create such a structure, who would drag into this work all the dregs of the provincial towns, who would make provincial shits into princesses of the capital, then fuck off.
(9) 5.15pm, and I'm harbouring serious reservations about the mental well-being of Guardian Unlimited Football's readership: "I am sitting alone in my serviced apartment in Singapore, wearing a Scotland top and boxer shorts like a Caledonian David Mellor, nursing the dregs of my one and only can of Tiger," writes Neil Cocker, in what can only be a cry for help.
(10) It's important to remember that Clearing isn't the dregs of the barrel," says Claire Chalmers, student recruitment officer at Goldsmiths, University of London.
(11) The DREG antibodies offer powerful tools for analyzing the role of homing receptors in human neutrophil-endothelial cell interactions, and also may prove valuable in the clinical assessment of neutrophil activation.
(12) The US, Canadian and Australian governments have chased the CCS dream with zeal, often using its compressed CO2 byproduct to prise away tar sands and eke out the dregs of depleted fossil fuel reserves.
(13) Moreover, mAb DREG-56 significantly diminished adhesion of healthy adult but not cord blood suspensions in the presence or absence of the anti-CD18 mAb R15.7.
(14) The DREG-56 mAb specifically inhibits greater than 90% of binding of human lymphocytes to HEVs within frozen sections of peripheral but not mucosal lymphoid tissue.
(15) These results demonstrate that the DREG mAbs define a human lymphocyte homing receptor for PLN HEVs and indicate that this human antigen is homologous to the MEL-14-defined murine lymphocyte homing receptor.
(16) That’s the only thing they understand.” Donald Trump’s presidential campaign energized and reanimated various pockets of far-rightwing America, from the dregs of the Ku Klux Klan represented by David Duke to the seemingly ascendant “alt-right”, members of which gathered in Washington DC after the election at a “thinktank” conference that saw audience members participate in Nazi salutes.
(17) These results suggest that monocytes are more affected than neutrophils in vivo by conditions expected to stimulate shedding of DREG and that sepsis promotes shedding of these adherence receptors.
(18) To test this hypothesis, we have analyzed the expression of DREG receptors on neutrophils and monocytes from 25 patients admitted to the Surgical Intensive Care Unit.
(19) For 14 nonseptic patients, mean monocyte positivity for DREG was reduced from 64% to 40%.
(20) One Love Manchester: pop's healing power rises from the dregs of depravity | Hannah Jane Parkinson Read more Some of the victims’ families had bristled at Grande hosting the concert so soon after the suicide bombing that killed 22 people , but her earnestness and emotional acuity meant that for thousands of people, this was an event that soothed and uplifted.
Drug
Definition:
(v. i.) To drudge; to toil laboriously.
(n.) A drudge (?).
(n.) Any animal, vegetable, or mineral substance used in the composition of medicines; any stuff used in dyeing or in chemical operations.
(n.) Any commodity that lies on hand, or is not salable; an article of slow sale, or in no demand.
(v. i.) To prescribe or administer drugs or medicines.
(v. t.) To affect or season with drugs or ingredients; esp., to stupefy by a narcotic drug. Also Fig.
(v. t.) To tincture with something offensive or injurious.
(v. t.) To dose to excess with, or as with, drugs.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(4) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(5) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(6) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(7) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(8) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(9) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(10) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(11) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(12) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(13) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(14) Further development of drug formulary concept was discussed, primarily for the drugs paid by the Health Insurance, as well as the unsatisfactory ADR reporting in Yugoslavia.
(15) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(16) The authors empirically studied the self-medication hypothesis of drug abuse by examining drug effects and motivation for drug use in 494 hospitalized drug abusers.
(17) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(18) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(19) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(20) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.