(n.) Any animal, vegetable, or mineral substance used in the composition of medicines; any stuff used in dyeing or in chemical operations.
(n.) Any commodity that lies on hand, or is not salable; an article of slow sale, or in no demand.
(v. i.) To prescribe or administer drugs or medicines.
(v. t.) To affect or season with drugs or ingredients; esp., to stupefy by a narcotic drug. Also Fig.
(v. t.) To tincture with something offensive or injurious.
(v. t.) To dose to excess with, or as with, drugs.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(4) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(5) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(6) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(7) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(8) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(9) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(10) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(11) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(12) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(13) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(14) Further development of drug formulary concept was discussed, primarily for the drugs paid by the Health Insurance, as well as the unsatisfactory ADR reporting in Yugoslavia.
(15) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(16) The authors empirically studied the self-medication hypothesis of drug abuse by examining drug effects and motivation for drug use in 494 hospitalized drug abusers.
(17) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(18) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(19) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(20) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
Play
Definition:
(n.) To engage in sport or lively recreation; to exercise for the sake of amusement; to frolic; to spot.
(n.) To act with levity or thoughtlessness; to trifle; to be careless.
(n.) To contend, or take part, in a game; as, to play ball; hence, to gamble; as, he played for heavy stakes.
(n.) To perform on an instrument of music; as, to play on a flute.
(n.) To act; to behave; to practice deception.
(n.) To move in any manner; especially, to move regularly with alternate or reciprocating motion; to operate; to act; as, the fountain plays.
(n.) To move gayly; to wanton; to disport.
(n.) To act on the stage; to personate a character.
(v. t.) To put in action or motion; as, to play cannon upon a fortification; to play a trump.
(v. t.) To perform music upon; as, to play the flute or the organ.
(v. t.) To perform, as a piece of music, on an instrument; as, to play a waltz on the violin.
(v. t.) To bring into sportive or wanton action; to exhibit in action; to execute; as, to play tricks.
(v. t.) To act or perform (a play); to represent in music action; as, to play a comedy; also, to act in the character of; to represent by acting; to simulate; to behave like; as, to play King Lear; to play the woman.
(v. t.) To engage in, or go together with, as a contest for amusement or for a wager or prize; as, to play a game at baseball.
(v. t.) To keep in play, as a hooked fish, in order to land it.
(n.) Amusement; sport; frolic; gambols.
(n.) Any exercise, or series of actions, intended for amusement or diversion; a game.
(n.) The act or practice of contending for victory, amusement, or a prize, as at dice, cards, or billiards; gaming; as, to lose a fortune in play.
(n.) Action; use; employment; exercise; practice; as, fair play; sword play; a play of wit.
(n.) A dramatic composition; a comedy or tragedy; a composition in which characters are represented by dialogue and action.
(n.) The representation or exhibition of a comedy or tragedy; as, he attends ever play.
(n.) Performance on an instrument of music.
(n.) Motion; movement, regular or irregular; as, the play of a wheel or piston; hence, also, room for motion; free and easy action.
(n.) Hence, liberty of acting; room for enlargement or display; scope; as, to give full play to mirth.
Example Sentences:
(1) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(2) The data indicate that ebselen is likely to be useful in the therapy of inflammatory conditions in which reactive oxygen species, such as peroxides, play an aetiological role.
(3) It involves creativity, understanding of art form and the ability to improvise in the highly complex environment of a care setting.” David Cameron has boosted dementia awareness but more needs to be done Read more She warns: “To effect a cultural change in dementia care requires a change of thinking … this approach is complex and intricate, and can change cultural attitudes by regarding the arts as central to everyday life of the care home.” Another participant, Mary*, a former teacher who had been bedridden for a year, read plays with the reminiscence arts practitioner.
(4) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(5) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(6) Because many wnt genes are also expressed in the lung, we have examined whether the wnt family member wnt-2 (irp) plays a role in lung development.
(7) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(8) Michael Caine was his understudy for the 1959 play The Long and the Short and the Tall at the Royal Court Theatre.
(9) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
(10) In concert with TF expressed by monocytes and macrophages this endothelial cell procoagulant activity may play a role in the pathogenesis of thrombotic disease.
(11) To determine whether or not the glycan moieties in hTPO play a role in the disease-associated epitopes in Hashimoto's thyroiditis, radiolabeled recombinant hTPO was immunoprecipitated after digestion with N-glycanase.
(12) Immunohistochemical observation of myoepithelial cells with monoclonal antibody from human mammalian cancer suggested that these cells play an important role in the process of glandular ducts formation.
(13) Anti-human factor V IgG decreased this enhanced thrombin formation in the presence of platelets, indicating that factor V from platelets was playing an important role in thrombin formation.
(14) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(15) The playing fields on which all those players began their journeys have been underfunded for years and are now facing a renewed crisis because of cuts to local authority budgets.
(16) The behaviour of DAO suggests that the enzyme plays an important role in the control of intracellular diamine concentration.
(17) It was with unanimous consent.” He denied that Trump’s tweets had played a part, saying: “No, no, no.
(18) When you have been out for a month you need to prepare properly before you come back.” Pellegrini will make his own assessment of Kompany’s fitness before deciding whether to play him in the Bournemouth game, which he is careful to stress may not be the foregone conclusion the league table might suggest.
(19) Photograph: Guardian The research also compiled data covered by a wider definition of tax haven, including onshore jurisdictions such as the US state of Delaware – accused by the Cayman islands of playing "faster and looser" even than offshore jurisdictions – and the Republic of Ireland, which has come under sustained pressure from other EU states to reform its own low-tax, light-tough, regulatory environment.
(20) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.