(n.) Any animal, vegetable, or mineral substance used in the composition of medicines; any stuff used in dyeing or in chemical operations.
(n.) Any commodity that lies on hand, or is not salable; an article of slow sale, or in no demand.
(v. i.) To prescribe or administer drugs or medicines.
(v. t.) To affect or season with drugs or ingredients; esp., to stupefy by a narcotic drug. Also Fig.
(v. t.) To tincture with something offensive or injurious.
(v. t.) To dose to excess with, or as with, drugs.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(4) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(5) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(6) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(7) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(8) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(9) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(10) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(11) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(12) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(13) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(14) Further development of drug formulary concept was discussed, primarily for the drugs paid by the Health Insurance, as well as the unsatisfactory ADR reporting in Yugoslavia.
(15) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(16) The authors empirically studied the self-medication hypothesis of drug abuse by examining drug effects and motivation for drug use in 494 hospitalized drug abusers.
(17) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(18) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(19) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(20) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
Schedule
Definition:
(n.) A written or printed scroll or sheet of paper; a document; especially, a formal list or inventory; a list or catalogue annexed to a larger document, as to a will, a lease, a statute, etc.
(v. t.) To form into, or place in, a schedule.
Example Sentences:
(1) Snooker, which became and remains a fixture in the BBC2 schedules, was chosen for showing because it is the sport in which different shades are most significant.
(2) A previous study, on grade IV astrocytomas, compared a combination of photons and fast neutron boost to photons only, both treatments being delivered following a concentrated irradiation schedule.
(3) The schedule proposed is easy to use and reproducible.
(4) In contrast, the late component of the thrombopoietic response was demonstrated best on the most toxic drug schedules.
(5) While the mouse P388 cells were sensitive to OP in vitro, no effect was seen when OP was administered in vivo, even when schedules designed to take advantage of OP's time-dependent toxicity were used.
(6) Comparison of the seroconversion results showed the presence of protective antibodies against all the 3 types of polio in 100% of the children in both the groups, but there was no statistical difference in the geometric mean antibody titre in the two immunization schedules.
(7) This schedule appears workable in the community setting and yields response rates similar to those reported for 5-FU with high-dose leucovorin, but without the gastroin testinal toxicity profile of the latter combination.
(8) No significant quantitative differences in AFB1-DNA adduct formation between the dietary groups were observed following the first exposure to [3H]AFB1; however, total aflatoxin-DNA adduct levels in the choline-deficient animals were significantly increased during the multiple dose schedule.
(9) After 40 programmed minutes of acquisition and 12 min of maintenance, without notice, both schedules changed to extinction for 28 min.
(10) These observations indicated a novel mechanism that in the absence of light-dark schedule, mothers taught the circadian rhythm to the pups as they raised them.
(11) Different possible combinations between neutrons and photons (boost, mixed schedule) are discussed.
(12) The interresponse-time reinforcement contingencies inherent in these schedules may actually mask the effects of overall reinforcement rate; thus differences in response rate as a function of reinforcement rate when interresponse-time reinforcement is eliminated may be underestimated.
(13) in rabbits according to schedules designed to yield approximately level activity in plasma for periods up to 5 hr.
(14) Squirrel monkeys trained to respond under a schedule in which each response postponed the delivery of electric shock developed a steady rate of responding.
(15) Twenty-four hours later, a stimulus generalization test was conducted in the absence of drug; during this session, tones that varied in frequency around 4.5 KHz were presented while the animals were responding under the VI schedule.
(16) It was found that DI rats responded less than LE rats on the progressive-ratio schedule and that DI rats suppressed drinking as much as LE rats at each concentration of quinine used on the drinking-suppression test.
(17) Two experiments reported the effects of prefeeding normal and septal rats prior to their daily sessions on a differential reinforcement of low rates (DRL-20) schedule.
(18) This dose and schedule of beta interferon did not result in significant anti-tumor effects in advanced NSCLC.
(19) Isoeffect distributions derived from time-dose fractionation values are examined, emphasizing alternate treatment schedules of the same plan.
(20) Our findings suggest that adoption of a sequential vaccination schedule (inactivated poliovirus vaccine followed by OPV) would be effective in decreasing the risk of VAPP while retaining the proven public health benefits of OPV.