(n.) Any animal, vegetable, or mineral substance used in the composition of medicines; any stuff used in dyeing or in chemical operations.
(n.) Any commodity that lies on hand, or is not salable; an article of slow sale, or in no demand.
(v. i.) To prescribe or administer drugs or medicines.
(v. t.) To affect or season with drugs or ingredients; esp., to stupefy by a narcotic drug. Also Fig.
(v. t.) To tincture with something offensive or injurious.
(v. t.) To dose to excess with, or as with, drugs.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(4) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(5) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(6) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(7) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(8) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(9) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(10) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(11) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(12) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(13) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(14) Further development of drug formulary concept was discussed, primarily for the drugs paid by the Health Insurance, as well as the unsatisfactory ADR reporting in Yugoslavia.
(15) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(16) The authors empirically studied the self-medication hypothesis of drug abuse by examining drug effects and motivation for drug use in 494 hospitalized drug abusers.
(17) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(18) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(19) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(20) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
Supplement
Definition:
(v. t.) That which supplies a deficiency, or meets a want; a store; a supply.
(v. t.) That which fills up, completes, or makes an addition to, something already organized, arranged, or set apart; specifically, a part added to, or issued as a continuation of, a book or paper, to make good its deficiencies or correct its errors.
(v. t.) The number of degrees which, if added to a specified arc, make it 180ยก; the quantity by which an arc or an angle falls short of 180 degrees, or an arc falls short of a semicircle.
(v. t.) To fill up or supply by addition; to add something to.
Example Sentences:
(1) Patient or fetal cord serum is commonly used as a protein supplement to culture media used in in-vitro fertilization (IVF).
(2) A survey carried out two and three years after the launch of the official campaign also showed a reduction in the prevalence of rickets in children taking low dose supplements equivalent to about 2.5 micrograms (100 IU) vitamin D daily.
(3) However, the presence of these two molecules was restored if testosterone was supplemented immediately after orchiectomy.
(4) In the 153 women to whom iron supplements were given during pregnancy, the initial fall in haemoglobin concentration was less, was arrested by 28 weeks gestation and then rose to a level equivalent to the booking level.
(5) A dietary supplementation is effective in preventing formation of DUs caused by cysteamine-HCl administration to rats.
(6) The enzyme activity can be raised to a plateau by Se supplements, but there is no evidence that supplementation leads to better health.
(7) Heparin prolonged by 15 s and 45 s the time required to demonstrate Factor V activation in CAP supplemented with Factor Xa and thrombin respectively.
(8) The findings reported here suggest that if women nurse exclusively for the 1st half year, maintaining night nursing after introducing supplements is important.
(9) During anaesthesia with 60-70 per cent N2O in O2 and 0.2 per cent isoflurane, a maintenance dose (MD) of fentanyl was administered using a continuous variable-rate IV fentanyl infusion, supplemented by intermittent 50 micrograms IV boluses.
(10) Supplemental heterologous bone was used in the first series of 51 cases, autologous bone in the second series of 67 cases, and no supplemental bone in the third series of 68 cases.
(11) Many patients with chronic obstructive pulmonary disease (COPD) receiving supplemental oxygen state that this treatment makes them less short of breath at rest.
(12) The onset of vitamin A deficiency had no effect on oviduct growth in these chicks; even though vitamin A-deficient chicks showed a severe decline in growth rate while controls (fed the same diet supplemented with retinyl palmitate) continued to grow, estrogen stimulated resulted in similar oviduct size.
(13) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
(14) The cardiorespiratory effects of trichloroethylene supplementation of nitrous oxide-oxygen anesthesia, with simultaneous use of halothane at induction as needed, were studied in outpatient oral surgery patients undergoing dental extractions under general anesthesia.
(15) To find out non-specific time related changes, vitamin supplemented and unsupplemented control groups of non-OC users were also examined.
(16) Potassium supplementation lowers blood pressure in hypertensive patients ingesting normal amounts of sodium.
(17) All reported studies have documented small 5 to 10 mm Hg decrements of blood pressure with dietary supplementation with these fatty acids and conversion of the ratio of polyunsaturated to saturated fatty acids toward unity.
(18) After 40 days of adaptation to serum-free medium, these cells displayed growth, morphology, and expression of CD4 similar to serum-supplemented cultures.
(19) A low-protein, low-phosphorus diet supplemented with essential amino acids and keto analogues was given to 12 rats, starting from the 90th day after subtotal nephrectomy.
(20) Two of them are vitamin K2-less (strains 30 and 73) and are supplemented by menadion natrium bisulfit at concentrations ranging from 0.2 to 10 mug per ml.