(n.) Any animal, vegetable, or mineral substance used in the composition of medicines; any stuff used in dyeing or in chemical operations.
(n.) Any commodity that lies on hand, or is not salable; an article of slow sale, or in no demand.
(v. i.) To prescribe or administer drugs or medicines.
(v. t.) To affect or season with drugs or ingredients; esp., to stupefy by a narcotic drug. Also Fig.
(v. t.) To tincture with something offensive or injurious.
(v. t.) To dose to excess with, or as with, drugs.
Example Sentences:
(1) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(4) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(5) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(6) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(7) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(8) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(9) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(10) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(11) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(12) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(13) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(14) Further development of drug formulary concept was discussed, primarily for the drugs paid by the Health Insurance, as well as the unsatisfactory ADR reporting in Yugoslavia.
(15) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(16) The authors empirically studied the self-medication hypothesis of drug abuse by examining drug effects and motivation for drug use in 494 hospitalized drug abusers.
(17) Inadequate treatment, caused by a lack of drugs and poorly trained medical attendants, is also a major problem.
(18) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(19) A remarkable deterioration of prognosis with increasing age rises the question whether treatment with cytotoxic drugs should be tried in patients more than 60 years old.
(20) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
Trap
Definition:
(v. t.) To dress with ornaments; to adorn; -- said especially of horses.
(n.) An old term rather loosely used to designate various dark-colored, heavy igneous rocks, including especially the feldspathic-augitic rocks, basalt, dolerite, amygdaloid, etc., but including also some kinds of diorite. Called also trap rock.
(a.) Of or pertaining to trap rock; as, a trap dike.
(n.) A machine or contrivance that shuts suddenly, as with a spring, used for taking game or other animals; as, a trap for foxes.
(n.) Fig.: A snare; an ambush; a stratagem; any device by which one may be caught unawares.
(n.) A wooden instrument shaped somewhat like a shoe, used in the game of trapball. It consists of a pivoted arm on one end of which is placed the ball to be thrown into the air by striking the other end. Also, a machine for throwing into the air glass balls, clay pigeons, etc., to be shot at.
(n.) The game of trapball.
(n.) A bend, sag, or partitioned chamber, in a drain, soil pipe, sewer, etc., arranged so that the liquid contents form a seal which prevents passage of air or gas, but permits the flow of liquids.
(n.) A place in a water pipe, pump, etc., where air accumulates for want of an outlet.
(n.) A wagon, or other vehicle.
(n.) A kind of movable stepladder.
(v. t.) To catch in a trap or traps; as, to trap foxes.
(v. t.) Fig.: To insnare; to take by stratagem; to entrap.
(v. t.) To provide with a trap; as, to trap a drain; to trap a sewer pipe. See 4th Trap, 5.
(v. i.) To set traps for game; to make a business of trapping game; as, to trap for beaver.
Example Sentences:
(1) Magnetic polyethyleneimine (PEI) microcapsules have been developed for trapping electrophilic intermediates in the gastrointestinal (GI) tract.
(2) tert-Butyl hydroaminoxyl is detected as a degradation product of the hydroxyl adduct from all spin traps.
(3) This suggests that the fusion protein traps the SII in nonstimulatory interactions and that antibody 2-7B inhibits SII binding to RNA polymerase II.
(4) The mosquitoes coming to bite in bedrooms were monitored with light traps set beside untreated bednets.
(5) They alter most immune functions and create a state of immunity deficiency; they damage the tubules which may lead to interstitial fibrosis and increased postglomerular capillary resistance furthering the trapping of macromolecules in the glomeruli; and they probably increase tissue permeability to macromolecules.
(6) Direct surgical exposure of the cervical or cavernous internal carotid artery (ICA) was necessary in the remaining 3 patients, who had undergone unsuccessful surgical trapping.
(7) One of the reasons for doing this study is to give a voice to women trapped in this epidemic,” said Dr Catherine Aiken, academic clinical lecturer in the department of obstetrics and gynaecology of the University of Cambridge, “and to bring to light that with all the virology, the vaccination and containment strategy and all the great things that people are doing, there is no voice for those women on the ground.” In a supplement to the study, the researchers have published some of the emails to Women on Web which reveal their fears.
(8) The estimated forward (k) and backward (1) rate constants are: 2.45 x I05 M-1 s- and 0.23 x 103 s-1, respectively, for k and I for the case when the drug is trapped by both activation and inactivation gates, and 3.58 x 105 M-l s-l and 4.15 x 10-3 S-l for the case when the drug is not trapped.
(9) These results suggest that [99mTc]LDL acts as a trapped ligand in vivo and should therefore, be a good tracer for noninvasive quantitative biodistribution studies of LDL.
(10) Godiya Usman, an 18-year-old finalist who jumped off the back of the truck, said she feels trapped by survivor's guilt.
(11) Relative to the rate of formation of the 3-oxo intermediate trapped with N-acetylcysteine, epoxidation of octene and subsequent hydrolysis to octane-1,2-diol was over 40 times more rapid.
(12) Charcoal was added to the homogenization buffer in these experiments to prevent the artifactual activation of PKA by cAMP analogs trapped in the extracellular space.
(13) Best fit of the thyroid data was achieved with a model in which the trap is described by two compartments, a fast ("follicular cell") compartment and a slower ("colloid") compartment.
(14) The aggregation product is of high molecular weight and composed of monomers which are trapped in a minium of conformational energy different from the one characterizing the native enzyme.
(15) A continuous fluorometric assay that utilizes apoflavodoxin as a trapping agent for riboflavin 5'-phosphate (FMN) has been developed for flavokinase (ATP:riboflavin 5'-phosphotransferase, EC 2.7.1.26).
(16) Solid-phase adsorbents were compared in their trapping efficiencies for dichloromethane (DCM), ethylene dibromide (EDB), 4-nitroblphenyl (4-NB), 2-nitrofluorene (2-NF), and fluoranthene (FI).
(17) Gas trapping and corneal edema were not observed in uncovered corneas or corneas covered with membrane lenses.
(18) The cells were trapped on glass fiber filters and incorporated radioactivity was measured.
(19) Based on these results we propose that the linearization of the DNA elution dose-response curve observed after chromatin decondensation reflects a reduction in the degree of chromatin compactness in the nuclear complexes that leads to a relatively uniform distribution of the DNA on the filter and reduces trapping of elutable material in the compact nuclear structures otherwise present.
(20) At this time the circulating MN population probably contained labeled long-lived lymphocytes that did not enter inflammatory sites (the traps) as readily as the short-lived lymphocytes.