(n.) The state of being dull; slowness; stupidity; heaviness; drowsiness; bluntness; obtuseness; dimness; want of luster; want of vividness, or of brightness.
Example Sentences:
(1) "Maybe dullness is associated with psychic pain," Wallace wrote at one point, "because something that's dull or opaque fails to provide enough stimulation to distract people from some other, deeper type of pain that is always there, if only in an ambient low-level way, and which most of us spend nearly all our time and energy trying to distract ourselves from."
(2) Similar systems were put in place at Dulles outside Washington DC, Newark and Chicago airports on Thursday.
(3) The soft, dull, malacic appearance of the center results from lack of a true surface layer of tangential collagen fibers.
(4) Here I am in Los Angeles being paid $30,000 to do next to nothing and still I'm finding life rather dull.
(5) A significant proportion of splenic B cells reacted with these mAb, although lower number (one-log less) than peritoneal B cells and a small proportion of H7dull+ splenic B cells seems to be Ly-1(CD5)dull+, 1 of 200 splenic B cells responded to IL-5 for IgM production.
(6) A 58-year-old man complained of dull left lower quadrant pain and constipation.
(7) They will begin next week at Liberty airport in Newark, New Jersey; Dulles, outside Washington DC; Chicago O’Hare, and Hartsfield-Jackson in Atlanta.
(8) At both observations, crowns were rated on 5-point Likert scales for outline form, porosity, smoothness, reflectance, texture, dullness, defects, and general esthetic appearances.
(9) On the other hand AMH2 showed the dull-positive reaction with some monocytes and pleural exudate cells among above-mentioned cells.
(10) Britain’s Got Talent review – Simon Cowell is looking like Caligula after a dull day at the Coliseum Read more The show, won last year by boy band Collabro, began eight years ago with 4.9 million viewers, rising to 8.8 million for its second series launch before hitting the 10 million mark for the first time in 2009 with 10.3 million.
(11) Disseminated annular psoriasiform lesions developed over a period of 2 months in a 48-year-old man with no preceding psoriatic history of drug intake, being accompanied by general dullness and arthralgia.
(12) 3) At the severe stage, pain and dullness at the back, numbness at arms and hands, hand coldness, sleep disturbance etc.
(13) One month after surgery, she complained of swelling and a dull pain in the right leg without cardiorespiratory symptoms.
(14) Black-hair follicular dysplasia in dogs of mixed breeding was delineated by hypotrichosis and dullness of most black regions of the coat.
(15) Endoscopic examination disclosed an almost roundish, smooth-surfaced, flat and dull red area corresponding to IIc (slightly depressed type).
(16) Their surface phenotype was Thy-1+(dull), Ly-1.2+(dull), Lyt-2-, L3T4-, 9F3+, and 3A1+, which is consistent with that found in intact lpr mice.
(17) The engines, gearboxes and even the doors now have a complexity that sees them constructed elsewhere, but the transformation on this line of the dull sheen of aluminium parts into a moving vehicle at the other end is still something to behold.
(18) Flow cytometry showed three types of trophozoite staining by mAb: (i) bright staining of greater than 90% of trophozoites, with aggregation of the organisms; (ii) bright staining of approximately 90% of trophozoites, with little or no aggregation; (iii) dull staining of approximately 20% of trophozoites, without aggregation.
(19) The percentage of dull CD8+CD11b+ cells (natural killer cells) among TG-2 cells was lower than that in peripheral blood, but there was no significant difference in bright CD8+CD11b+ cells (suppressor-effector T cells) between thyroid glands and peripheral blood.
(20) It was filed in my mind as a pretty but dull destination, full of pensioners on package deals and cruises.
Opiate
Definition:
(n.) Originally, a medicine of a thicker consistence than sirup, prepared with opium.
(n.) Any medicine that contains opium, and has the quality of inducing sleep or repose; a narcotic.
(n.) Anything which induces rest or inaction; that which quiets uneasiness.
(a.) Inducing sleep; somniferous; narcotic; hence, anodyne; causing rest, dullness, or inaction; as, the opiate rod of Hermes.
(v. t.) To subject to the influence of an opiate; to put to sleep.
Example Sentences:
(1) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(2) Opiate agonists and endogenous opioid peptides inhibit electrolyte secretion both in vitro and in vivo.
(3) It appears that tricyclic antidepressants act in a fashion different from opiate drugs that alter the sensory discriminative component of pain.
(4) The results are discussed with reference to the possible mechanism(s) via which injected and endogenous opiates may affect motor performance by attenuating GABA transmission in the nigra.
(5) Pharmacological data suggest that opiates, acting indirectly via the catecholaminergic system, are involved in the inhibition of LH release and the stimulation of PRL secretion.
(6) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(7) From these results, we conclude that opiate peptides are released in response to the suckling stimulus in the cynomolgus monkey and that they mediate the effects of suckling on PRL secretion in both gonadal-intact and agonadal cynomolgus monkeys.
(8) Its potency is 4-5 times greater than that of the opiate antagonist naloxone.
(9) A cost-effective immunoassay for the detection of opiates in urine has been developed using commercial reagents on a centrifugal analyser.
(10) Drugs used to promote food intake and weight gain, such as cyproheptadine, amitriptyline, clonidine and opiate antagonists, have provided disappointing results.
(11) An alternative approach, which correlates the structure-activity data of opiate compounds with that of the enkephalins, is described and shown to produce a model consistent with the available structure-activity data.
(12) However, opiate treatment is not a new therapeutic concept in psychiatry.
(13) The inhibitory response was not decreased by treatment with atropine, hexamethonium, yohimbine or naloxone, suggesting that muscarinic, nicotinic, alpha 2 adrenergic or opiate receptors were not being stimulated.
(14) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(15) We report that exposure of rat spinal cord-dorsal root ganglion cocultured neurons to kappa-opiate agonist is accompanied by a 60-70% reduction in the level of the alpha i subunit of GTP-binding proteins.
(16) Cerebrospinal fluid (CSF) opiate activity has been found to be elevated in two studies.
(17) PBEir increased with both opiates immediately after initiation of CPB and remained so during the rest of the study.
(18) Diclofenac is an alternative to opiates in the management of postoperative pain.
(19) On the other hand, if the tissue-derived opiates were from prodynorphin, only Leu-enkephalin should be found.
(20) Analysis of patient questionnaires suggests more enthusiasm for patient-controlled analgesia, but in this study, it was difficult to clearly demonstrate any significant advantage for pain management or amount of opiate administered.