(v. t.) To cure, as codfish, in a particular manner, by laying them, after salting, in a pile in a dark place, covered with salt grass or some like substance.
(v. t. & i.) To ask or beset, as a debtor, for payment; to urge importunately.
(n.) One who duns; a dunner.
(n.) An urgent request or demand of payment; as, he sent his debtor a dun.
(a.) Of a dark color; of a color partaking of a brown and black; of a dull brown color; swarthy.
Example Sentences:
(1) These data indicate that the muscarinic receptor in Dunning H tumors is of M3 type.
(2) In order to assess prostatic tissue as a target for receptor-mediated estrogen action, we have examined the regulation of estrogen (ER) and progestin receptors (PgR) by estrogen, antiestrogen, and progesterone in cytosolic and nuclear fractions of the R3327H (Dunning) prostatic adenocarcinoma of the rat.
(3) Transferrin-mRNA, expressed in the male urogenital tract and also in the liver and other tissues, was detected in the mammary gland and Dunning tumor, but not in the dorsolateral prostate.
(4) The Dunning R3327 prostate adenocarcinoma of the Copenhagen rat was developed as a suitable model of human prostate cancer.
(5) A number of chemotherapeutic agents, including L-asparaginase, actinomycin D, chloroethylcyclohexy-nitrosourea, 5-flourouracil, cyclophosphamide, hydroxyurea, cis-platinum, adriamycin and methotrexate, alone and in combination and at variable dose levels, were applied against the Dunning R3327 rat prostatic adenocarcinoma-subline G. We found a continuing parallel between responses of the human and rat tumors and conclude that the usefulness of this animal model as a screening system for agents against the human tumor is further supported.
(6) The R3327H-G8-A1 cell line derived from the Dunning rat prostate adenocarcinoma contains both androgen and glucocorticoid receptors.
(7) Rats bearing Dunning mammary tumors (DMBA 5A) of more than 2 g absorbed 70-100% more of an intragastric copper dose than controls, and a much larger percentage was found in the plasma, with less in liver and kidney.
(8) The Dunning R-3327-H is a well-differentiated transplantable rat prostatic adenocarcinoma that contains both hormone-sensitive and -insensitive cells.
(9) The complete DNA sequence of human papovavirus BKV(Dun), consisting of 5153 nucleotide pairs, is presented.
(10) The proliferation of primary and serially-cultured epithelial cells from androgen-responsive Dunning R3327 rat prostate tumors was also androgen-independent, but exhibited dramatic alterations in response to hormones that stimulated normal cell proliferation.
(11) In our experimental systems, in vivo, pentosan inhibits the growth of the highly metastatic MAT-LyLu (MLL) Dunning R3327 prostate cancer cell line only at toxic doses and has no apparent effect on growth in vitro.
(12) These results indicate that most actin exists in a depolymerized form as a cytosol protein of 41,000 daltons in the Dunning tumor and is composed of at least four isomers.
(13) Dunning hepatoma ribosomes were resistant to 4 mM EDTA.
(14) The growth of a transplantable rat prostatic carcinoma (Dunning R3327H) was studied after castration, testosterone substitution or testosterone substitution in combination with oestradiol treatment.
(15) Table: Countrywide Nick Dunning, group commercial director at Countrywide, said: "2013 saw the focus of demand shift sharply northwards after several years of more stable levels of supply and demand.
(16) The effects of two inhibitors of ornithine decarboxylase activity, alpha-difluoromethylornithine (DMFO) and (2R,5R) 6-heptyne-2,5 diamine (HDA), and an inhibitor of S-adenosylmethionine decarboxylase, methylglyoxal bis-guanylhydrazone (MGBG), were tested on casein kinase activity and endogenous phosphorylation in the cytosol fractions of mouse thyroid and a rat prostate tumor model, Dunning R 3327 MAT LyLu subline.
(17) Using the Dunning R-3327 rat prostate animal tumor model we have previously shown that an increase in cell surface charge, as measured by individual cell electrophoresis, is associated with an increase in metastatic ability.
(18) She had learned by then not to back off from unpleasant facts - such as that, in her view, she was fat and ugly, something that her not very clever family had dunned into her.
(19) Cytogenetic analysis of the two least progressionally advanced Dunning cancers (i.e., histologically well-differentiated, slow-growing, nonmetastatic variants) demonstrated no structural or numerical chromosomal aberration, suggesting that the initial development of prostatic cancer may not require detectable cytogenetic changes.
(20) In a preliminary study, the effect of transfer factor (TF), one form of passive immunotherapy, on tumor-associated immunity (TAI) and tumour growth and histology of the G subline (a poorly differentiated, fast-growing, androgen sensitive, and poorly metastatic tumour of the Dunning R-3327 rat PCa) has been evaluated.
Dup
Definition:
(v. t.) To open; as, to dup the door.
Example Sentences:
(1) The oxazolidinone compound E3709, which contains a 4-pyridyl group, was found to be more active in vitro than other members of this series, such as DuP 721.
(2) The effects of A-II on inhibition of cortisol secretion in response to ACTH and the activation of phosphoinositidase-C in response to A-II alone were both fully antagonized by DuP 753, but not by PD 123319.
(3) However, the DUP will decide on support for the Conservatives on other issues in parliament on a vote-by-vote basis.
(4) DuP 753 at 10(-6) M, added before or after EXP3892, reversed partially the depressed AII maximal response caused by 10(-9) M EXP3892.
(5) Five children have the derivative chromosome 2 resulting in del (2)(q31q33) and one individual received the derivative chromosome 6 leading to dup (2)(q31q33).
(6) Nine of the 12 fetuses had either bilateral cystic hygroma of the neck (7 cases) or nuchal bleb (2 cases: trisomy 13 and dup 6q).
(7) In addition, this condition appears to be milder than other duplications of the short arm of chromosome 17, namely trisomy 17p and dup(17)(p11.2----cen).
(8) Creasy said Green “did not deny abortion has been discussed” in negotiations with the DUP.
(9) To determine if chronic treatment with DuP 753 was able to inhibit the pressor response to angiotensin II, a single i.v.
(10) The in vitro binding properties of 1-(cyclopropylmethyl)-4-(2'-(4''-fluorophenyl)-2'-oxoethyl)pipe ridi ne HBr, [3H]DuP 734, a novel sigma receptor ligand, were examined in homogenates of guinea pig brain.
(11) 6i (DuP 734), 6q, 18a, and 18n) have the best in vivo potency.
(12) Normal rats and three groups of clipped rats were studied: an untreated group (HYP), a group treated with captopril (CEI), and a group treated with DuP 753 (DuP) 5 days before micropuncture.
(13) Northern Ireland is the only remaining part of the UK where same-sex marriage is not legal after the DUP used a controversial veto mechanism to block any change to legislation.
(14) Chromosome analysis from peripheral blood of the patient showed a recombinant chromosome 16 [46, XY, rec (16), dup (p13.1----p13.3) del (q22----q24)].
(15) There’s not going to be a summer budget or anything like that.” Pressed on whether the government would have to change direction, particularly if it did a deal with the DUP, which is opposed to cuts to the winter fuel allowance and the end of the triple lock on pensions, he replied: “We will look at all these things.
(16) Furthermore, Dup 721 did not cause phenotypic suppression of nonsense mutations suggesting that DuP 721 did not inhibit peptide chain termination.
(17) Higher morbidity in controls than in DuP 753-treated rats was also suggested by body weights.
(18) But hardline Traditional Unionist Voice leader, Jim Allister, accused Robinson and the DUP of a U-turn on their threats on Wednesday that they would all resign from the executive.
(19) And its leader is married to Iris Robinson, the former DUP health spokeswoman who said gay people could be cured .
(20) Addition of AII to the submucosal but not the mucosal side increased the release of prostaglandin E2, an effect that was abolished by DuP 753.