(v. t.) To cure, as codfish, in a particular manner, by laying them, after salting, in a pile in a dark place, covered with salt grass or some like substance.
(v. t. & i.) To ask or beset, as a debtor, for payment; to urge importunately.
(n.) One who duns; a dunner.
(n.) An urgent request or demand of payment; as, he sent his debtor a dun.
(a.) Of a dark color; of a color partaking of a brown and black; of a dull brown color; swarthy.
Example Sentences:
(1) These data indicate that the muscarinic receptor in Dunning H tumors is of M3 type.
(2) In order to assess prostatic tissue as a target for receptor-mediated estrogen action, we have examined the regulation of estrogen (ER) and progestin receptors (PgR) by estrogen, antiestrogen, and progesterone in cytosolic and nuclear fractions of the R3327H (Dunning) prostatic adenocarcinoma of the rat.
(3) Transferrin-mRNA, expressed in the male urogenital tract and also in the liver and other tissues, was detected in the mammary gland and Dunning tumor, but not in the dorsolateral prostate.
(4) The Dunning R3327 prostate adenocarcinoma of the Copenhagen rat was developed as a suitable model of human prostate cancer.
(5) A number of chemotherapeutic agents, including L-asparaginase, actinomycin D, chloroethylcyclohexy-nitrosourea, 5-flourouracil, cyclophosphamide, hydroxyurea, cis-platinum, adriamycin and methotrexate, alone and in combination and at variable dose levels, were applied against the Dunning R3327 rat prostatic adenocarcinoma-subline G. We found a continuing parallel between responses of the human and rat tumors and conclude that the usefulness of this animal model as a screening system for agents against the human tumor is further supported.
(6) The R3327H-G8-A1 cell line derived from the Dunning rat prostate adenocarcinoma contains both androgen and glucocorticoid receptors.
(7) Rats bearing Dunning mammary tumors (DMBA 5A) of more than 2 g absorbed 70-100% more of an intragastric copper dose than controls, and a much larger percentage was found in the plasma, with less in liver and kidney.
(8) The Dunning R-3327-H is a well-differentiated transplantable rat prostatic adenocarcinoma that contains both hormone-sensitive and -insensitive cells.
(9) The complete DNA sequence of human papovavirus BKV(Dun), consisting of 5153 nucleotide pairs, is presented.
(10) The proliferation of primary and serially-cultured epithelial cells from androgen-responsive Dunning R3327 rat prostate tumors was also androgen-independent, but exhibited dramatic alterations in response to hormones that stimulated normal cell proliferation.
(11) In our experimental systems, in vivo, pentosan inhibits the growth of the highly metastatic MAT-LyLu (MLL) Dunning R3327 prostate cancer cell line only at toxic doses and has no apparent effect on growth in vitro.
(12) These results indicate that most actin exists in a depolymerized form as a cytosol protein of 41,000 daltons in the Dunning tumor and is composed of at least four isomers.
(13) Dunning hepatoma ribosomes were resistant to 4 mM EDTA.
(14) The growth of a transplantable rat prostatic carcinoma (Dunning R3327H) was studied after castration, testosterone substitution or testosterone substitution in combination with oestradiol treatment.
(15) Table: Countrywide Nick Dunning, group commercial director at Countrywide, said: "2013 saw the focus of demand shift sharply northwards after several years of more stable levels of supply and demand.
(16) The effects of two inhibitors of ornithine decarboxylase activity, alpha-difluoromethylornithine (DMFO) and (2R,5R) 6-heptyne-2,5 diamine (HDA), and an inhibitor of S-adenosylmethionine decarboxylase, methylglyoxal bis-guanylhydrazone (MGBG), were tested on casein kinase activity and endogenous phosphorylation in the cytosol fractions of mouse thyroid and a rat prostate tumor model, Dunning R 3327 MAT LyLu subline.
(17) Using the Dunning R-3327 rat prostate animal tumor model we have previously shown that an increase in cell surface charge, as measured by individual cell electrophoresis, is associated with an increase in metastatic ability.
(18) She had learned by then not to back off from unpleasant facts - such as that, in her view, she was fat and ugly, something that her not very clever family had dunned into her.
(19) Cytogenetic analysis of the two least progressionally advanced Dunning cancers (i.e., histologically well-differentiated, slow-growing, nonmetastatic variants) demonstrated no structural or numerical chromosomal aberration, suggesting that the initial development of prostatic cancer may not require detectable cytogenetic changes.
(20) In a preliminary study, the effect of transfer factor (TF), one form of passive immunotherapy, on tumor-associated immunity (TAI) and tumour growth and histology of the G subline (a poorly differentiated, fast-growing, androgen sensitive, and poorly metastatic tumour of the Dunning R-3327 rat PCa) has been evaluated.
Torment
Definition:
(n.) An engine for casting stones.
(n.) Extreme pain; anguish; torture; the utmost degree of misery, either of body or mind.
(n.) That which gives pain, vexation, or misery.
(v. t.) To put to extreme pain or anguish; to inflict excruciating misery upon, either of body or mind; to torture.
(v. t.) To pain; to distress; to afflict.
(v. t.) To tease; to vex; to harass; as, to be tormented with importunities, or with petty annoyances.
(v. t.) To put into great agitation.
Example Sentences:
(1) Her story is an incredible tale of triumph over tragedy: a tormented childhood during China's Cultural Revolution, detention and forced exile after exposing female infanticide – then glittering success as the head of a major US technology firm.
(2) "It is difficult to imagine the torment experienced by the vulnerable victims of crimes such as these.
(3) While his citizens were being beaten and tormented in illegal detention, spokesmen for the then prime minister, Tony Blair, declared: "The Italian police had a difficult job to do.
(4) Yet the removal of two in-form goalscorers who were tormenting West Ham – first Aaron Lennon and then Lukaku – afforded the visitors the initiative.
(5) Through small and large acts of deprivation and destruction we follow the process: the removal of hope, of dignity, of luxury, of necessity, of self; the reduction of a man to a hoarder of grey slabs of bread and the scrapings of a soup bowl (wonderfully told all this, with a novelist's gift for detail and sometimes very nearly comic surprise), to the confinement of a narrow bed – in which there is "not even any room to be afraid" – with a stranger who doesn't speak your language, to the cruel illogicality of hating a fellow victim of oppression more than you hate the oppressor himself – one torment following another, and even the bleak comfort of thinking you might have touched rock bottom denied you as, when the most immediate cause of a particular stress comes to an end, "you are grievously amazed to see that another one lies behind; and in reality a whole series of others".
(6) Corner to USA though... 1.33am BST 20 mins More tempo in the American play now, but Belgium intercept again, and Mirallas torments them down the Belgian right flank before hitting a low cross in that's hoofed safely clear.
(7) It cannot be right that anyone who has found the courage to escape their abusive or violent partner should be subjected to the stress and torment of being confronted and interrogated by them in any court.” Research by charity Women’s Aid suggests a quarter of women in family court proceedings have been cross-examined by an abusive former partner.
(8) Shin Dong-hyuk said he was tormented to see his father alive and speaking in the video released by Pyongyang in October.
(9) In a torment of frustration, Mohammed stood outside the governor's and threw a can of petrol over himself.
(10) More than a quarter of hospital beds are occupied by people with dementia (no surprise to anyone who has been in hospital recently, where wards are full of men and women in great anxiety and torment) and they tend to stay for longer-than-average periods of time.
(11) Senator Jack Reed, a Democrat from Rhode Island whose bipartisan bill will ensure a three-month extension of the federal benefits program, told the Guardian the measure would stimulate the economy and alleviate what he called the “mental torment” suffered by those long-term unemployed who now feel abandoned.
(12) It was only his inflexible determination, the quality that had made him a great general, that mastered the torments of ill-health – sleepless nights, fear of dying – to articulate his account for a devoted American audience.
(13) The man who devised these torments has a passing resemblance to El Greco's emaciated saints.
(14) Arsenal had no riposte to the blue and white striped waves that tormented them all evening.
(15) Father Michael, so brilliantly played by Sean Bean , was tormented by one such moment: his decision not to answer the phone to Helen Oyenusi (Muna Otaru) when she called to ask that he calm down her son.
(16) Suárez played as through affronted by the suggestion he might have fitness issues, tormenting England’s defence on a night that finished as a personal ordeal for Steven Gerrard.
(17) So often did John torment his elder brother – because, grouchy alcoholic prick that he was, he hated to acknowledge a debt – one has to wonder if he cast Francis in a minor part in Young Mr Lincoln simply to let him witness, day after day, his own signature role being forever obliterated by Henry Fonda's entrancing new reading.
(18) Shawcross, however, maintains there was no bad intent and said for that reason he has not been tormenting himself about the moment he collided with Ramsey's right leg and left the teenager writhing in agony.
(19) Since his withdrawal from the music scene, Shields has earned a reputation as the latter-day Brian Wilson, a tormented genius unable to produce a successor to Loveless, the Pet Sounds of UK avant-rock.
(20) Adding to the torment for Rodgers was a 120-minute performance before hosting Manchester City in the Premier League on Sunday at noon.