(n.) One backward in book learning; a child or other person dull or weak in intellect; a dullard; a dolt.
Example Sentences:
(1) Mutant alleles of rutabaga act in the germ line cells to partially suppress the developmental defects caused by dunce mutations.
(2) Mutant dunce flies have elevated levels of cAMP and exhibit a number of defects including learning deficiencies and female sterility.
(3) These homologies, together with prior genetic and biochemical studies, provide unambiguous evidence that dunce+ codes for a phosphodiesterase.
(4) The recovery of clones from the differential screen demonstrates that in addition to altering normal behavior, fertility, and cAMP metabolism, dunce mutation confers an alteration in the level of expression of certain genes.
(5) The cDNA clone defines dunce exons which are separated by a large intron of 79 kb.
(6) We have isolated several genes expressed at abnormal levels in the memory mutant, dunce (dnc), of Drosophila melanogaster.
(7) It is basic maths – not so much the Wolf of Wall Street, more the Dunce of Downing Street."
(8) The nucleotide sequence of this clone led to the identification of a dunce exon included in at least one transcript so far uncharacterized.
(9) In addition, the dunce+ gene product shares a seven-amino acid sequence with a regulatory subunit of cAMP-dependent protein kinase that is predicted to be part of the cAMP binding site.
(10) Not all are convinced that Pisa officials should don the dunce cap.
(11) We have isolated and sequenced cDNA clones representing portions of the polyadenylylated transcripts of the dunce+ gene.
(12) Winter Garden Theatre, New York, starts 9 November A Confederacy of Dunces John Kennedy Toole didn’t live long enough to see the publication of his celebrated comic novel, so he definitely isn’t around for the theatrical adaptation, which will premier at the Huntington with designs on a Broadway run.
(13) The molecular organization of the dunce gene of Drosophila melanogaster has proved to be particularly complex, with two divergently transcribed genes, Sgs-4 and Pig-1, nested within its 79 kb intron (1).
(14) Female columnists have not been kind to the group in retrospect; Caitlin Moran basically blamed "Girl Power" for the loss of interest in feminism, while Grace Dent went further by saying that "any student in 2012 who regurgitates this Spice Girls-helped-feminism baloney in a dissertation should have the whole thing shredded and be made to wear a dunce cone in graduation pics".
(15) Selection of mutations that suppress dunce sterility has led to the isolation of two rutabaga alleles.
(16) The deduced amino acid sequences of part of this region were also homologous to the D. melanogaster dunce PDE and to PDEs from bovine and yeast.
(17) Two dunce mutants examined show aberrant RNA expression from this coding region, confirming that this region is the dunce gene.
(18) A probe representing the Drosophila dunce+ (dnc+) gene, the structural gene for a cAMP phosphodiesterase (PDEase), detects homologous sequences in many different organisms, including mouse, rat, and human.
(19) In both dunce and rutabaga larvae, voltage-clamp analysis of neuromuscular transmission revealed impaired synaptic facilitation and post-tetanic potentiation as well as abnormal responses to direct application of dibutyryl cAMP.
(20) Coisogenic lines were constructed which varied at the dunce gene (dnc+ and dncM14 alleles) in order to test this hypothesis.
Dune
Definition:
(n.) A low hill of drifting sand usually formed on the coats, but often carried far inland by the prevailing winds.
Example Sentences:
(1) We have developed the DUNE (Diagnostic Understanding of Natural Events) system architecture that organizes the knowledge around processing structures.
(2) Israeli media reports said the rocket came down near an amusement park in sand dunes on the edge of the city.
(3) I will sometimes make my way there by bicycle and spend the night sleeping on dunes under the stars.
(4) At Pelican Island, a 2.5 mile strip in the Barataria Bay, crews used 2.5m cubic yards of sand and silt mined from the Gulf of Mexico to build dunes and marshes, and rolled out protective fences around newly planted grasses.
(5) Enjoy riding through the natural beauty of pine forests and open heathland, before taking the Sand Worm (a tractor-trailer ride) across vast sand dunes to the colliding waves of the North and Baltic seas.
(6) To our right, four miles of wide clean beach, fringed by bumpy low sand dunes sprouted here and there with couch grass, flowering creepers and low bushes.
(7) Facebook Twitter Pinterest Donald Trump on the sand dunes of the Menie estate.
(8) In this paper, we discuss the general specifications for a program that can aid psychiatric diagnoses, and then describe DUNE and its capabilities.
(9) The region boasts some of the world's highest dunes, with gazelles among the wildlife.
(10) Open 5 April- 30 September, camping from €18.20 a night for two, cabins from €51 a night for five Camping Le Pin Sec, Naujac-sur-Mer, near Bordeaux Amid pine forests and dunes just 50 metres from the sea, is a pop-up camp where surfers can stay in tipis with beds, carpets and electricity.
(11) It is one of the most beautiful beaches in Brazil, and backed by Atlantic rainforest, with dunes, sandbanks, a lake and rocky coastline.
(12) In between come the honky-tonk towns of Texas, the cactus-studded desert of New Mexico and Arizona, and the dunes and mountain passes of California.
(13) For example, dune fires broke out in the coastal parts of the Netherlands at the start of May .
(14) The path runs through a wild and protected area of dunes, woodland and heathlands with views of the islands in the Gulf of Morbihan.
(15) There is something of the sea cave and the sand dune about them.
(16) I was with a group of friends in the Namib desert, which has the largest sand dune in the world.
(17) The tombs nestle in the dunes below the Red Pyramid, considered the pharaohs' first successful attempt at a smooth-sided structure.
(18) The planning inspectors ruled that the damage to the dunes was outweighed by the resort's substantial value to the economy - a judgment challenged by the Royal Society for the Protection of Birds.
(19) River water after dune infiltration or pure dune water, collected in closed systems, as well as aerobic or anaerobic groundwater, were usually free of Aeromonas in 100 ml.
(20) Oregon Dunes does a great job of keeping the quieter foot-traffic-only areas separate from the motorised off-highway vehicle areas.