(n.) One backward in book learning; a child or other person dull or weak in intellect; a dullard; a dolt.
Example Sentences:
(1) Mutant alleles of rutabaga act in the germ line cells to partially suppress the developmental defects caused by dunce mutations.
(2) Mutant dunce flies have elevated levels of cAMP and exhibit a number of defects including learning deficiencies and female sterility.
(3) These homologies, together with prior genetic and biochemical studies, provide unambiguous evidence that dunce+ codes for a phosphodiesterase.
(4) The recovery of clones from the differential screen demonstrates that in addition to altering normal behavior, fertility, and cAMP metabolism, dunce mutation confers an alteration in the level of expression of certain genes.
(5) The cDNA clone defines dunce exons which are separated by a large intron of 79 kb.
(6) We have isolated several genes expressed at abnormal levels in the memory mutant, dunce (dnc), of Drosophila melanogaster.
(7) It is basic maths – not so much the Wolf of Wall Street, more the Dunce of Downing Street."
(8) The nucleotide sequence of this clone led to the identification of a dunce exon included in at least one transcript so far uncharacterized.
(9) In addition, the dunce+ gene product shares a seven-amino acid sequence with a regulatory subunit of cAMP-dependent protein kinase that is predicted to be part of the cAMP binding site.
(10) Not all are convinced that Pisa officials should don the dunce cap.
(11) We have isolated and sequenced cDNA clones representing portions of the polyadenylylated transcripts of the dunce+ gene.
(12) Winter Garden Theatre, New York, starts 9 November A Confederacy of Dunces John Kennedy Toole didn’t live long enough to see the publication of his celebrated comic novel, so he definitely isn’t around for the theatrical adaptation, which will premier at the Huntington with designs on a Broadway run.
(13) The molecular organization of the dunce gene of Drosophila melanogaster has proved to be particularly complex, with two divergently transcribed genes, Sgs-4 and Pig-1, nested within its 79 kb intron (1).
(14) Female columnists have not been kind to the group in retrospect; Caitlin Moran basically blamed "Girl Power" for the loss of interest in feminism, while Grace Dent went further by saying that "any student in 2012 who regurgitates this Spice Girls-helped-feminism baloney in a dissertation should have the whole thing shredded and be made to wear a dunce cone in graduation pics".
(15) Selection of mutations that suppress dunce sterility has led to the isolation of two rutabaga alleles.
(16) The deduced amino acid sequences of part of this region were also homologous to the D. melanogaster dunce PDE and to PDEs from bovine and yeast.
(17) Two dunce mutants examined show aberrant RNA expression from this coding region, confirming that this region is the dunce gene.
(18) A probe representing the Drosophila dunce+ (dnc+) gene, the structural gene for a cAMP phosphodiesterase (PDEase), detects homologous sequences in many different organisms, including mouse, rat, and human.
(19) In both dunce and rutabaga larvae, voltage-clamp analysis of neuromuscular transmission revealed impaired synaptic facilitation and post-tetanic potentiation as well as abnormal responses to direct application of dibutyryl cAMP.
(20) Coisogenic lines were constructed which varied at the dunce gene (dnc+ and dncM14 alleles) in order to test this hypothesis.
Gump
Definition:
(n.) A dolt; a dunce.
Example Sentences:
(1) In 1995, a year after his novel Forrest Gump had been sanitised for the screen, Winston Groom published Gump and Co , a sequel, which began with: "Let me say this: Everybody makes mistakes ...
(2) That might sometimes be true – Forrest Gump , I'm looking at you – but there's also a difference in the way a film is consumed.
(3) Facebook Twitter Pinterest The film team review Jurassic World At Bubba Gump, he recognised a customer: Rae Dawn Chong, an actor who had appeared in 80s hits Commando and The Color Purple.
(4) In the oral cavity, a "flail" mandible, an "Andy Gump" deformity, and a sublingual hematoma may occur.
(5) It paid $400,000 over the past year to a Washington lobby group, Akin Gump Strauss Hauer & Feld, to work on Capitol Hill to work for the removal of the MEK from the list of foreign terrorist organisations.
(6) In an interview with CNBC, Ma said he believed that his customers and employees should come before shareholders, but added: “I am very honoured and so excited … the responsibility I’ve been thinking about the next five to 10 years is: how can I make sure these shareholders are happy?” Ma told CNBC that he had got the idea for his business when he visited the US, and looks to Forrest Gump for inspiration.
(7) July 12, 2015 Pop culture mashups And in that last recourse for the commentator searching desperately for a joke, the internet opened the pop culture vault and hastily cut up everything from Forrest Gump – “ run, Chapo, run ” – to Frozen – “ I’m free, I’m free!
(8) Are you stupid, Mr Gruber?” the committee chairman Darryl Issa asked Jonathan Gruber, before comparing the professor to the film character Forrest Gump.
(9) Not even seven Oscar nominations could help it compete with the success of hits such as Speed, Pulp Fiction and Forrest Gump.
(10) As a youth he dabbled in stand-up comedy and did a spot of stripping (once for a friend’s grandmother) before – at the age of 19 – moving to Maui for a year, living in a van and waiting tables at Bubba Gump Shrimp Co.
(11) Gump n Hell gave it an Indonesian spin, featuring Piko Taro using an apple and a banana to create the shape of the communist icon, the hammer and sickle.
(12) The major finding in these patients was rib resorption and deteriorating cosmetic appearance and development of "Andy Gump" deformity.
(13) We will hope for our best but it is like Forrest Gump and his box of chocolates.
(14) And he was, at the Bubba Gump Shrimp Company franchise in Hawaii, by actor Rae Dawn Chong, which at least has the ring of Lana Turner at the counter of Schwab’s Pharmacy.
(15) The end result was a consensus that, like Forrest Gump, Slahi popped up around significant events by coincidence, not design.
(16) Premier League: 10 things to look out for this weekend Read more “I’m a little bit like Forrest Gump, like this,” Flores says, miming the style of the movie character and laughing loudly.
(17) Boundary-pushing satire, in the form of comics such as Gump n Hell , are also starting to emerge.
(18) Alibaba was founded by Jack Ma, a former English teacher who counts Forrest Gump as his inspiration.
(19) Even though Hanks achieved his greatest career success appearing in dramas in the 90s, such as Apollo 13 and winning his Oscars for (in typical Oscars style) his two worst films, Philadelphia and Forrest Gump , as well as appearing in romcoms ( Sleepless in Seattle , You've Got Mail ) written and directed by Nora Ephron ("She was a taskmaster, but gentle – I wish I was making a movie with Nora tomorrow"), I personally will always have a soft spot for his 80s comedic performances.
(20) Our techniques in reconstruction of the oral cavity, hypopharynx, esophagus, nose, Andy-Gump deformities (anterior jaw complex resection), pharyngo-orocutaneous fistulas, and radionecrosis of the mandible are presented.