(a.) Excited by desire in the pursuit of any object; ardent to pursue, perform, or obtain; keenly desirous; hotly longing; earnest; zealous; impetuous; vehement; as, the hounds were eager in the chase.
(a.) Brittle; inflexible; not ductile.
(n.) Same as Eagre.
Example Sentences:
(1) Beijing has no interest in seeing strained ties affecting development plans either.” The Moranbong band was founded by Kim Jong-un , with each member reportedly selected by a leader eager to make his mark on the cultural scene.
(2) The reason behind Burnham's impregnable new confidence may well also explain the coalition's eagerness to drive him on to the backbenches.
(3) Eager to show I was a good student, the next time we had sex, I noticed that one of my hands was, indeed, lying idle – and started to pat him on the back, absently, as if trying to wind a baby.
(4) Driven by a desire to reduce dependence on imported fossil fuels and promote a secure supply of energy, the government of Albania has been very eager to encourage increased investment in renewable energy and in 2013 a law was passed to promote renewable energy .
(5) Certainly the affidavit against Ferdaus paints a compelling picture of a man hellbent on waging jihad in America and eager to take the guns and explosives eventually supplied to him by the undercover FBI agents.
(6) Wide-eyed, tentative and much given to confidences – her voice falls to an eager whisper when she's really dishing – she seems far younger than her years.
(7) Coleman, in his efforts to sustain the national team's momentum, will be particularly eager to keep Craig Bellamy in the lineup, although it was the persuasiveness of Speed that brought his return.
(8) "EA's next CEO inherits a company beset by a broad range of legacy problems created not just by difficult retail market conditions but also by its own hand," says Nick Gibson an analyst at Games Investor Consulting Ltd. "It has been too eager to use major acquisitions – Jamdat, Playfish, Bioware, PopCap etc – to try to accelerate growth or gain early leadership positions in emerging markets, often overpaying by substantial amounts for companies that subsequently fail to deliver what EA expected they would."
(9) Nor should we forget why the Conservatives were so eager to seize that chance: they saw the opportunity to wipe out the achievements of Tony Blair and Gordon Brown, who demonstrated, over many years of hard graft, that the country’s economic management was safe in Labour’s hands.
(10) Boris Johnson, the mayor, has been accused of being too eager to allow developers to change the skyline.
(11) With a high level of English gleaned from an Erasmus stint in Oxford, she was eager to move to London.
(12) That report, due July 2 , is eagerly anticipated by both the NSA and its critics, as it is likely to add momentum to either side in the ongoing legislative debate on the scope surveillance.
(13) Hence the tearing-off-the-arm eagerness to seize the opportunity.
(14) The nuptials drew crowds of fans eager to witness the glitzy event, but they were kept far away from the heavily walled 16th-century fortress, which offers stunning views of Florence and surrounding Tuscan hills.
(15) Kipsang will be running in London in one of the most eagerly anticipated races in history.
(16) People eagerly accept such evidence-free claims "because the alternative mean[s] confronting outright mendacity from otherwise respected authorities, trading the calm of certainty for the disquiet of doubt".
(17) I'm sure that advisers are at fault: mediocre people with PR degrees, eagerly advising on how to avoid the resentment of the masses.
(18) Many are first- or second-generation immigrants from places such as Afghanistan, Poland, Somalia and Nigeria eager to sign up to drive for the US tech company, whose phone-based minicab-hailing app has transformed the taxi industry in 58 countries.
(19) Randomized trials comparing BCG and chemotherapy are in progress and are eagerly awaited.
(20) To bail themselves out of the NBA's worst crisis of credibility since the Tim Donaghy officiating scandal, the easy part for the NBA will be enlisting the eagerness and financial muscle of Magic Johnson and Mark Walter of the Guggenheim Partners – owners of the Los Angeles Dodgers .
Twitcher
Definition:
(n.) One who, or that which, twitches.
Example Sentences:
(1) In the twitcher mice with BMT examined at ages 44 and 71 days (transplanted at the day 9 to 12), degeneration of oligodendrocytes and myelin was still present.
(2) Also, the established twitcher cells were crossed with neomycin-resistant control human fibroblasts and selected in G418 medium.
(3) The assay conditions for both these activities in several mouse tissues have been optimized to facilitate the enzymatic characterization of homozygous and heterozygous twitcher mice.
(4) Although extensive demyelination was noted in the CNS of both mice and additionally, macrophage infiltration was pronounced in the twitcher, BBB remained intact to horseradish peroxidase.
(5) Boiled supernatant fractions, which contained saposins, were prepared from homogenates of twitcher brain, liver, kidney, and spleen.
(6) Twitcher mice which were previously given colloidal carbon intravenously, had some Mac-1 positive cells which contained carbon particles both in the CNS and PNS.
(7) Although psychosine levels in sciatic nerves of HCT-treated twitcher mice increased more slowly than in the nerves of untreated twitchers, the levels in 100-day-old HCT-treated twitcher mice had reached the same high values as those seen in untreated 40-day-old twitchers.
(8) The effect on the activity of galactosylceramide beta-galactosidase as well as 4-methylumbelliferyl-beta-glucoside beta-glucosidase in the twitcher brain and liver homogenates by authentic saposin A and C was similar to that in control tissues.
(9) To determine whether Krabbe patients' cells complement twitcher cells to produce, in hybrid combination, greater than deficient levels of galactocerebrosidase activity, five separate crosses were made between an established twitcher mouse cell line and five cell strains from unrelated Krabbe disease patients.
(10) After postnatal day 10, the number of Schwann cell-axon units gradually increased and the number of unmyelinated axons per unit progressively decreased in the twitcher mouse.
(11) However, marked accumulation of psychosine was found in the 30-day-old-twitcher DRG.
(12) These data correlate well with the pathological changes; tissues containing higher concentrations of galactosylsphingosine show earlier and more severe pathological changes than those containing lower concentrations, thereby indicating the close link of galactosylsphingosine to the pathogenesis of the twitcher mouse.
(13) In attempts to elucidate the origin of accumulated galactosylsphingosine in the twitcher mouse, a murine model of human globoid cell leukodystrophy (Krabbe's disease), UDP-galactose:sphingosine galactosyltransferase activity was assayed in tissues from normal and twitcher mice.
(14) The addition of a foetal brain cell graft to haemopoietic cell transplantation resulted in significantly prolonged survival of twitcher mice.
(15) Examination of the KR1787 strain has shown that it also exhibits mutator activity as assayed by the spontaneous mutation frequency at the unc-22 (twitcher) locus.
(16) These findings suggest that galactosylsphingosine is cytotoxic for myelin-forming cells and is closely related to pathogenetic events in the twitcher mouse.
(17) Thus, these alterations of unmyelinated Schwann cells in the twitcher mouse suggest that attenuated branching of cellular processes develops at an early stage and progresses together with progression of demyelination in this mutant.
(18) There was no apparent difference of lipid composition between control and twitcher DRG, and the galactocerebroside levels from control were similar to those of twitcher.
(19) There's a brief flurry of excitement as some passing twitchers point out four hobbies overhead.
(20) Several of the hybrid lines from both crosses had higher than deficient levels of galactocerebrosidase activity initially, followed by a decrease to twitcher levels during subculture, whereas other lines retained high levels of activity.