(1) We have used the bivalent reagent 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDAC) to cross-link 125I-alpha-Btx (M(r) = 8 kDa) to Drosophila head membranes.
(2) The optimal conditions for toxoiding a pertussis toxin (PT) preparation with 1-ethyl-3(3-dimethylaminopropyl) carbodiimide.HCl (EDAC) were determined.
(3) N,N'-dicyclohexylcarbodiimide (DCCD) slightly stimulates ATPase activity in both vacuole and protoplast suspensions, whereas ethyl-3-(3-dimethylaminopropyl carbodiimide) (EDAC) strongly inhibits.
(4) An EDAC-toxoid also manifested no late histamine-sensitising activity.
(5) The synthesis was carried out by condensing on the complementary matrix two heptanucleotides, one of which possessed at the 3'-end a glycine residue, connected with the oligonucleotide by the phosphoramide bond, whereas the 5'-end phosphate group of the other was activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDAC).
(6) The prime factor affecting the toxoiding of PT was the EDAC to protein ratio.
(7) EDAC-mediated inhibition of pullulan alpha 1-6-bond hydrolysis was relieved by amylose or pullulan.
(8) When the EDAC concentration used was sufficient (500 mM) to inactivate almost all of the opioid receptors, the modification was partly prevented by inclusion of high concentrations (100 microM) of opioid agonists ([D-Ala2, MePhe4, Glyol5]-enkephalin, [D-Ala2, D-Leu5]-enkephalin,(+)-trans-N-methyl-N-[2-(1-pyrrolidinyl)- cyclohexyl]benzo(b)thiophene-4-acetamide hydrochloride), although they exhibited equal efficacy irrespective of their mu, delta or kappa type selectivity.
(9) Skeletal-muscle UDP-glucose pyrophosphorylase is inactivated by reaction with 2-ethoxy-N-(ethoxy-carbonyl)-1,2-dihydroquinoline (EEDQ) and 1-(3-dimethylaminopropyl-3-ethylcarbodi-imide (EDAC), two reagents specific for carboxylate groups.
(10) Under this condition, however, cyclic photophosphorylation was much less sensitive to the inhibitors DBMIB, EDAC and antimycin A, but remained completely sensitive to DSPD and KCN.
(11) Ethylenediamine monocarbamate (synthetic EDAC) released [3H]-GABA from preloaded segments of ileum maintained in bicarbonate-free KPO or KHO solution containing amino-oxyacetic acid and beta-alanine, the release being sensitive to 3-mercaptopropionic acid which prevents GABA release.
(12) Water-soluble carbodiimide (EDAC) proved to be more efficient in the phosphate group activation than N-hydroxybenzotriazole ester (yields of substituted pyrophosphates 35-80 and 10-15% respectively).
(13) Cyclic photophosphorylation driven by white light, as followed by 14CO2 fixation by mesophyll chloroplast preparations of the C4 plant Digitaria sanguinalis, was specifically inhibited by disalicylidenepropanediamine (DSPD), antimycin A, 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone (DBMIB), 1-ethyl-3(3-dimethyl-aminopropyl)-carbodiimide (EDAC), and KCN suggesting that ferredoxin, cytochrome b563, plastoquinone, cytochrome f, and plastocyanin are obligatory intermediates of cyclic electron flow.
(14) We have used the soluble covalent cross-linking agent 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDAC) to examine the capacity of epidermal growth factor (EGF) to stimulate the dimerization of purified EGF receptor, of EGF receptor in membrane preparations and in intact A431 cells.
(15) Opioid receptors in membranes prepared from guinea-pig cerebellum were modified irreversibly by treatment with a water soluble carbodiimide, 1-ethyl,3-(3-dimethylaminoethyl)carbodiimide (EDAC).
(16) 4 GABA-mimetic responses were induced by EDAC in the isolated ileum maintained in bicarbonate-free KPO solution, as was a delta-aminovalerate-sensitive depression of ileal twitch responses elicited by transmural stimulation, all of which were also sensitive to 3-mercaptopropionic acid.
(17) The data indicated that the use of EDAC for toxoiding PT in a B. pertussis extract is a simple and reproducible procedure and should be considered as a method for the production of acellular pertussis vaccines.
(18) An enantiospecific assay for biological material was developed that is based on chiral derivatization of PCA with N-ethyl-N'-(3-dimethylaminopropyl)carbodiimide (EDAC) and the primary amine S-FLOPA, a chiral coupling component for carboxylic acids derived from S-flunoxaprofen, followed by HPLC resolution.
(19) A ratio of 40-80: 1 EDAC to protein by weight was optimal for abolishing the acute toxicity, histamine-sensitising and leucocytosis-promoting activities associated with PT, whilst maintaining the antigenicity of the vaccine antigens.
(20) Modification with 1-(3-dimethylaminopropyl)-3-ethylcarbodi-imide (EDAC) confirmed this view, and analysis of the order of reaction and inactivation kinetics suggested the presence of a single carboxy group at a catalytic centre of the active site.
Rapacity
Definition:
(n.) The quality of being rapacious; rapaciousness; ravenousness; as, the rapacity of pirates; the rapacity of wolves.
(n.) The act or practice of extorting or exacting by oppressive injustice; exorbitant greediness of gain.
Example Sentences:
(1) Scott's film, which starred Noomi Rapace, Charlize Theron, Michael Fassbender and Idris Elba, centred on the human crew of a spaceship sent to investigate a distant planet where the answers to mankind's origins may lie hidden.
(2) Gandolfini, who died of a heart attack last June at the age of 51, features alongside Tom Hardy and Noomi Rapace in the Brooklyn-set film, which is directed by Oscar-nominated Belgian film-maker Michael R Roskam.
(3) A combination of uncontrolled breeding and rapacity is propelling us down the slippery slope 1st envisioned by Malthus, dragging the rest of the planet along.
(4) It's totally appropriate for government to regulate the terms of sale of a harmful product, and to safeguard public health from corporate rapacity – in the same way we've done with tobacco.
(5) This is why Britain’s historical amnesia about the rapacity of its rule in India is so deplorable.
(6) When his bar is hit by a gang of robbers, he sees his life and those of his cousin Marv (Gandolfini) and partner Nadia (Rapace) thrown into chaos.
(7) The Wrap suggests the sequel will continue where the first movie left off, with Rapace's God-fearing archeologist accompanying Fassbender's David on a journey to find the home of the Engineers, a mysterious alien race with a genetic link to homo sapiens.
(8) This is the era of the dotcom boom and, in the literary world, the rapid expansion of the list of Andrew Wylie , the agent known as "the Jackal" for his rapacity; a time of dizzying auctions, huge advances for authors, and newly short lunches.
(9) However, more recently, his ability to capture the demolition of the soul of decent people, as the social contract between citizen and government is ripped apart by the rapacity of neoliberalism, has hit a wider target.
(10) The film, which stars Charlize Theron, Michael Fassbender, Noomi Rapace, Guy Pearce and Idris Elba, opens in the UK on 1 June.
(11) The Sopranos star, who died of a heart attack on 19 June in Italy, appears as a bar owner, opposite Tom Hardy and Noomi Rapace, in the film.
(12) Many modern apologists for British colonial rule in India no longer contest the basic facts of imperial exploitation and plunder, rapacity and loot, which are too deeply documented to be challengeable.
(13) The Barcelona attacker has now struck 43 times for his country, but individual rapacity cannot necessarily keep pace with a Germany line-up that has won its knockout phase fixtures 4-1, against England, and 4-0, against Argentina.
(14) The broadcaster cut to an ad break following a graphic scene of a "disturbing rape" of the film's main character Lisbeth Salander, played by actress Noomi Rapace, which included a close-up of her screaming.
(15) James Gandolfini’s penultimate film, Nicole Holofcener’s Enough Said , screened to great warmth at the festival last year; this year, there’s a premiere for his final film, The Drop , co-starring Tom Hardy and Noomi Rapace and shot just before his death in June 2013 .
(16) Doubly ironic, then, that we were the real Martians, and that many people – including quite a few scientists – believe that we're accomplishing that same scenario with equal rapacity.
(17) Tomorrow he's flying out to start work on Dead Man Down with Noomi Rapace, for director Niels Arden Oplev, who shot the Swedish-language version of The Girl With The Dragon Tattoo .
(18) The name Black Friday perfectly captures the heedless, bushfire rapacity of the event.