(v. t.) The thin cutting side of the blade of an instrument; as, the edge of an ax, knife, sword, or scythe. Hence, figuratively, that which cuts as an edge does, or wounds deeply, etc.
(v. t.) Any sharp terminating border; a margin; a brink; extreme verge; as, the edge of a table, a precipice.
(v. t.) Sharpness; readiness of fitness to cut; keenness; intenseness of desire.
(v. t.) The border or part adjacent to the line of division; the beginning or early part; as, in the edge of evening.
(v. t.) To furnish with an edge as a tool or weapon; to sharpen.
(v. t.) To shape or dress the edge of, as with a tool.
(v. t.) To furnish with a fringe or border; as, to edge a dress; to edge a garden with box.
(v. t.) To make sharp or keen, figuratively; to incite; to exasperate; to goad; to urge or egg on.
(v. t.) To move by little and little or cautiously, as by pressing forward edgewise; as, edging their chairs forwards.
(v. i.) To move sideways; to move gradually; as, edge along this way.
(v. i.) To sail close to the wind.
Example Sentences:
(1) Brown's model, which goes far further than those from any other senior Labour figure, and the modest new income tax powers for Holyrood devised when he was prime minister, edge the party much closer to the quasi-federal plans championed by the Liberal Democrats.
(2) Everyone is expecting them to win and I think that’s a double-edged sword.
(3) In fact, the lowest-rated game of last year's World Series between the Giants and the Tigers edged out the opening round of the draft by only 2.4 million viewers.
(4) In one case MRI showed a false image of tear of the supra spinatus m. on its anterior edge.
(5) Flexion of the knee beyond 40 degrees progressively diminished viability of the edges of the wound, particularly the lateral edge.
(6) Fibrinogen was scattered in the intercellular spaces, and located in the inner layer or edges of the thickened intima of the bifurcation with increasing plaque formation.
(7) After 1 day in vitro the explants were partly encircled by epithelium which had proliferated from the cut edges of the explant and from rete ridges near the cut edge (epiboly).
(8) This kind of distribution of microfilaments was always associated with resorption lacunae, and F-actin, vinculin, and talin zones correspond roughly to the edge of lacunae.
(9) Mario Balotelli’s life on the edge leaves him asking: why not me any more?
(10) Shenhua Watermark Coal, a subsidiary of the Chinese state-owned Shenhua Group, is waiting for final approval from Hunt for a $1.2bn open-cut coalmine on the edge of the plains, a little more than three kilometres from Hamparsum’s property.
(11) Three disks of different sizes (10, 25, and 45 mm in diameter) were attached to the edge of the baresthesiometer, and pressures of 1, 3 and 5 kg were applied to the 10 mm disk, and 1, 3, 5, and 7 kg to the other disks.
(12) The expansion comes hot on the heels of another year of stellar growth in which Primark edged closer to overtaking high street stalwart M&S in sales and profits.
(13) Under the electron microscope, slices appeared vacuolated near the cut surfaces, but well preserved internally (greater than 40 micron from the edge).
(14) Following orthodontic treatment the canine's incisal edge occlusion demonstrates the tip and torque present in the appliance that was used.
(15) Attenuation compensation causes more noise to appear in the center than the edge for both modes and an average increase in uncertainty of 30%.
(16) Perisic darts in from the edge of the penalty area to get on the end of it and thumps a meaty header wide.
(17) The transversalis fascia of the floor of the femoral canal turns down to form the medial wall of the venous compartment of the femoral sheath, and has the support of the curved edge of the lacunar ligament which effectively bars the femoral canal from entering the thigh.
(18) Trout fishing is excellent in both, and after they fall over the edge of the Piedmont Plateau to the Atlantic Coastal Plain, the lower stretches of both waterways boil into class-2 and -3 whitewater for kayakers and canoeists.
(19) Oxytocin-like immunoreactive neurons were observed to lie within 77 nm of the edge of the lumen of capillary blood vessels.
(20) A formal notion of relatability is defined, specifying which physically given edges leading into discontinuities can be connected to others by interpolated edges.
Substrate
Definition:
(n.) A substratum.
(a.) Having very slight furrows.
(v. t.) To strew or lay under anything.
Example Sentences:
(1) 5-HT thus appears to be the preferred substrate for uptake into platelets and for movement from cytoplasm to vesicles.
(2) Some common eye movement deficits, and concepts such as 'the neural integrator' and the 'velocity storage mechanism', for which anatomical substrates are still sought, are introduced.
(3) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(4) The common polyamines, spermidine and spermine, and histones were not substrates.
(5) Manometric studies with resting cells obtained by growth on each of these sulfur sources yielded net oxygen uptake for all substrates except sulfite and dithionate.
(6) The PSB dioxygenase system displayed a narrow substrate range: none of 18 sulphonated or non-sulphonated analogues of PSB showed significant substrate-dependent O2 uptake.
(7) The observed relationship between prorenin and renin substrate concentrations might be a consequence of their regulation by common factors.
(8) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(9) Yields of Thiobacillus dentrificans on different substrates were compared.
(10) It includes preincubation of diluted plasma with ellagic acid and phospholipids and a starting reagent that contains calcium and a chromogenic peptide substrate for thrombin, Tos-Gly-Pro-Arg-pNA.
(11) The present results provide no evidence for a clear morphological substrate for electrotonic transmission in the somatic efferent portion of the primate oculomotor nucleus.
(12) Fluorination with [18F]acetylhypofluorite yields 6-[18F]fluoro-L-dopa with 95% radiochemical purity; fluorination of the same substrate with [18F]F2 yields a mixture of all three structural isomers in a ratio of 70:16:14 for 6-, 5-, and 2-fluoro compounds.
(13) The enzyme, when assayed as either a phospholipase A2 or lysophospholipase, exhibited nonlinear kinetics beyond 1-2 min despite low substrate conversion.
(14) The stopped-flow technique was used to measure the rate constants for the reactions between the oxidized forms of peroxidase with luminol and the following substrates: p-iodophenol, p-bromophenol, p-clorophenol, o-iodophenol, m-iodophenol, luciferin, and 2-iodo-6-hydroxybenzothiazole.
(15) The time-course and dose-response for this modification of pp60c-src paralleled PDGF-induced increases in phosphorylation of pp36, a major cellular substrate for several tyrosine-specific protein kinases.
(16) Control incubations revealed an inherent difference between the two substrates; gram-positive supernatants consistently contained 5% radioactivity, whereas even at 0 h, those from the gram-negative mutant released 22%.
(17) Uptake could be supported either by substrate oxidation or by adenosine 5'-triphosphate (ATP), and was inhibited in the former case by antimycin or cyanide, in the latter case by oligomycin, and in both cases by 2,4-dinitrophenol.
(18) These results indicate that both the renal brush-border and basolateral membranes possess the Na(+)-dependent dicarboxylate transport system with very similar properties but with different substrate affinity and transport capacity.
(19) Congenitally deficient plasmas were used as the substrate for the measurement of procoagulant activities in a one-stage clotting assay.
(20) This capacity is expressed during incubation of the bacteria with the substrate and needs a source of carbon and other energy metabolites.