(1) Synovectomy of the elbow is highly effective even when performed relatively late (stage 3 according to Larsen-Dahle-Eek) insofar as pain relief and swelling are concerned.
(2) Sometime, somewhere in the limitless future it will be listened to, and, if there is intelligent life in another galaxy and creatures from outer space do land on earth having learned English from BBC broadcasts, the chances are they will not say 'Take me to your leader' but 'How bona to vada your dolly old eek!'"
(3) The virus produced cytopathic effects (CPE) in equine embryo kidney (EEK) cell culture, contained deoxyribonucleic acid (DNA), was resistant to chloroform and pH 3, and was moderately resistant to heat.
(4) Sixteen protected NAc-tetrapeptide amides were studied, namely the variants of DEKS: NEKS, EEKS, DDKS, DQKS, NQKS, DERS, NERS, EERS, DDRS, NDRS, DQRS, and DKES.
(5) The extreme C-terminus of the NF-M tail contains two highly conserved homologous sequences each of 15 amino acids, with the consensus EEK-V-TKKVEK-TS, plus another very closely related 7 amino acid sequence.
(6) 3.09am BST Eek, Mitt Romney – asked to respond about his crappy "self-deportation" thing, decides to relitigate some old answers he's obviously still fuming about.
(7) Most of you managed to get this one right ... " They would frequently reinvent language - "How bona to vada your dolly old eek" meant "How nice to see you" in Julian and Sandyspeak.
(8) The predicted eek protein contains all the amino acid residues conserved in the catalytic domains of protein-tyrosine kinases and is most similar to two putative receptor protein-tyrosine kinases of the eph subclass, elk (69%) and eph (57%).
(9) Human genomic DNAs encoding part of eek (EEK) as well as another putative protein-tyrosine kinase most similar to elk (90%), ERK (elk-related kinase), were isolated and partially characterized.
(10) PBMC isolated from these foals at different days after inoculation did not display appreciably reduced or elevated NK cytotoxicities against Chang liver cells and EHV-1-infected EEK targets, when compared with that of a PBMC reference from a healthy adult horse.
(11) In Northern blot analysis of rat RNA, DNAs encoding rat eek and human ERK hybridized to transcripts most abundant in brain and lung, respectively.
(12) Chang liver, rabbit kidney (RK-13), equine sarcoid (ES) and embryonic equine kidney (EEK) cells were more susceptible when presented to horse PBMC than monolayer cultures.
(14) Cytotoxicity against EHV-1-infected EEK cells developed faster, between 4 and 8 h of incubation and reaching a maximum at 24 h. By contrast, cytotoxicity against uninfected fibroblasts was not significant until approximately 16 h of incubation with maximum cytotoxicity observed between 32 h and 48 h. Specific pathogen-free (SPF) foals were inoculated with live EHV-1.
(15) The indications for each of three operative methods were presented with clinical assessment and Larsen, Dahle, Eek scale of radiological changes taken into consideration.
(16) Rat cDNA clones encoding eek (eph- and elk-related kinase) were isolated from a brain cDNA library probed with DNA encoding the kinase region of the insulin receptor-related receptor.
(17) In Manhattan’s chi-chi Sant Ambroeus restaurant, the pair of smartly dressed women at the next table are making not-so-surreptitious “eek” faces at each other, having clocked that their neighbour for lunch is Taylor Swift .
(18) Horse PBMC demonstrated higher levels of NK-type activity against EEK, EEL and RK-13 cells infected with equine herpesvirus 1 (EHV-1) compared with uninfected cells.
(19) It's like a real-life cartoon, with all the sound effects – thump, thwack, bang, crash, eek, splat – as they roll, bite each other and tumble slowly off their bamboo platform on to the grass.
(20) These two new members of the eph subclass of receptor protein-tyrosine kinases, eek and erk, may therefore have tissue-specific functions distinct from those of other eph family members.
Erke
Definition:
(a.) ASlothful.
Example Sentences:
(1) PK46 and PK42 comigrated with proteins that reacted with antibodies against extracellular signal-regulated kinases (ERKs).
(2) Activation of the ERKs requires both threonine and tyrosine phosphorylation suggestive of a key role in mediating intracellular events in response to extracellular cues.
(3) Expression of oncogenic ras in PC12 cells causes neuronal differentiation and sustained protein tyrosine phosphorylation and activity of extracellular signal-regulated kinases (ERKs), p42erk2 and p44erk1.
(4) We now describe cloning and characterization of two ERK1-related kinases, ERK2 and ERK3, and provide evidence suggesting that there are additional ERK family members.
(5) Bacterial expression of mouse gene Erk-1 yielded an active kinase with the same substrate specificity shown for ERK1 protein purified from rat cells.
(6) The bt-Erk-1 protein also had the capacity to reactivate the ribosomal protein S6 kinase (S6KII).
(7) In this communication we describe assays utilizing the Erk-1 protein fused to glutathione S-transferase that permit the identification of protein kinase(s) that phosphorylate and activate the myelin basic protein kinase activity encoded by the Erk-1 gene.
(8) These results indicate that ERKs mediate signal transduction by ET.
(9) Because both Ras and the microtubule-associated protein 2 kinases ERK1 and ERK2 have been implicated in events that lead to neurite outgrowth, we explored the possibility that Ras and ERKs may lie on the same signaling pathway.
(10) Chromosomes have been manipulated within mitotic human embryonic lung, ERK, and HeLa cells.
(11) The antibodies detect ERKs in cell lines from multiple species, including human, mouse, dog, chicken, and frog, in addition to rat, indicating that the kinases are conserved across species.
(12) The antibodies recognize both ERK1; a closely related kinase, ERK2; and a third novel ERK-related protein.
(13) Reactivity with anti-ERK-1 antibodies was observed only in the precipitate of chemoattractant-stimulated cells.
(14) Oncogenic N-ras-induced neuronal differentiation is inhibited by compounds that block ERK protein tyrosine phosphorylation or ERK activity, indicating that ERKs are not only activated by p21ras but serve as the primary downstream effectors of p21ras.
(15) Treatment of PC12 cells with nerve growth factor or fibroblast growth factor results in neuronal differentiation and in a sustained elevation of p21ras activity, of ERK activity, and of ERK tyrosine phosphorylation.
(16) The regulation of the Erk (extracellular-signal-regulated kinase) gene-encoded protein kinase activity by reversible phosphorylation has been reported to involve either an activator of autophosphorylation or an upstream protein kinase.
(17) Here we show that interleukin-2 selectively stimulates the phosphorylation and activation of p70 S6 kinase but not the erk-encoded MAP kinases and rsk-encoded S6 kinases.
(18) Studies with cultured cells, Xenopus, and sea star oocytes have furthered our understanding of possible functions of Erks in vivo.
(19) Treatment of intact PC12 cells with bradykinin or NGF increased both the phosphorylation of TH-Ser31 in situ and the catalytic activity of ERKs (measured subsequently in vitro with myelin basic protein as substrate).
(20) Conversion of the tyrosine site of phosphorylation to phenylalanine yielded an Erk-1 gene product that could not be activated.