What's the difference between effect and efficacy?

Effect


Definition:

  • (n.) Execution; performance; realization; operation; as, the law goes into effect in May.
  • (n.) Manifestation; expression; sign.
  • (n.) In general: That which is produced by an agent or cause; the event which follows immediately from an antecedent, called the cause; result; consequence; outcome; fruit; as, the effect of luxury.
  • (n.) Impression left on the mind; sensation produced.
  • (n.) Power to produce results; efficiency; force; importance; account; as, to speak with effect.
  • (n.) Consequence intended; purpose; meaning; general intent; -- with to.
  • (n.) The purport; the sum and substance.
  • (n.) Reality; actual meaning; fact, as distinguished from mere appearance.
  • (n.) Goods; movables; personal estate; -- sometimes used to embrace real as well as personal property; as, the people escaped from the town with their effects.
  • (v. t.) To produce, as a cause or agent; to cause to be.
  • (v. t.) To bring to pass; to execute; to enforce; to achieve; to accomplish.

Example Sentences:

  • (1) Indicators for evaluation and monitoring and outcome measures are described within the context of health service management to describe control measure output in terms of community effectiveness.
  • (2) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
  • (3) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
  • (4) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
  • (5) AEDs may also have differential effects on nighttime sleep.
  • (6) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
  • (7) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
  • (8) Combination therapy was most effective in patients receiving HCTZ prior to enalapril.
  • (9) Age difference did not affect the mean dose-effect response.
  • (10) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
  • (11) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (12) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
  • (13) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
  • (14) Omission of K(+), Ca(++) or Mg(++) had no effect on uptake.
  • (15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
  • (16) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
  • (17) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
  • (18) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
  • (19) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
  • (20) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).

Efficacy


Definition:

  • (n.) Power to produce effects; operation or energy of an agent or force; production of the effect intended; as, the efficacy of medicine in counteracting disease; the efficacy of prayer.

Example Sentences:

  • (1) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
  • (2) The rise of malaria despite of control measures involves several factors: the house spraying is no more accepted by a large percentage of house holders and the alternative larviciding has only a limited efficacy; the houses of American Indians have no walls to be sprayed; there is a continuous introduction of parasites by migrants.
  • (3) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
  • (4) These findings raise questions regarding the efficacy of medical school curriculum in motivating career choices in primary care.
  • (5) Accidentally discovered nearly 40 years ago as the first true antidepressants, the MAOIs soon fell into disfavor due to concerns about toxicity and seemingly lesser efficacy compared with the newer tricyclic compounds.
  • (6) In patients who had undergone gastric operations, the efficacy of a parenteral rehabilitation with plasma, human albumin and Aminofusin L forte was determined by assessing the extravascular albumin pool.
  • (7) It is especially efficacious in evaluating patients with cystic lesions, especially those with complex cysts not clearly of water density.
  • (8) The efficacies of pefloxacin, fosfomycin, and both of these agents in combination against methicillin-resistant Staphylococcus aureus were assessed in a rat endocarditis model.
  • (9) It is concluded that extradural adrenaline does not usefully reduce systemic absorption of 0.5% bupivacaine, but may improve its efficacy in extradural anaesthesia for elective Caesarean section.
  • (10) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
  • (11) We evaluated the safety and efficacy of a conjugate vaccine that links the H. influenzae type b capsular polysaccharide to the outer-membrane protein complex (OMPC) of Neisseria meningitidis serogroup B.
  • (12) Addition of IL7 either alone, or in combination with low doses of IL2, resulted in the generation of CTL with significantly (6-8-fold) enhanced therapeutic efficacy in vivo.
  • (13) The efficacy of the process is dependent on immersion medium, while the degree of surrounding tissue damage is dependent on energy dose.
  • (14) However, self-efficacy (defined as confidence in being able to resist the urge to drink heavily) assessed at intake of treatment, was strongly associated with the level of consumption on drinking occasions at follow-up.
  • (15) The objective of this work was to determine the efficacy of an endoscopic approach coupled to a Nd:YAG laser fiber in performing arytenoidectomy.
  • (16) and (4) Compared to the instruction provided by instructors from other medical and academic disciplines, do paediatric residents perceive differences in the teaching efficacy and clinical relevance of instruction provided by paediatricians?
  • (17) A prospective randomized trial involving 64 patients with bleeding peptic ulcers was performed to assess the efficacy of two modalities of injection therapy.
  • (18) A randomised double-blind trial comparing this preparation with a so-called 'shotgun' combination containing 0.05% betamethasone 17-valerate, 0.1% gentamicin, 1.0% tolnaftate and 1.0% clioquinol in 288 patients in the Philippines resulted in a better efficacy for the diflucortolone preparation in the 80 patients with bacterially or mycotically infected skin diseases.
  • (19) With attention to proper performance and patient selection, spinal and epidural anaesthesia are safe and efficacious options when choosing anaesthetic technique.
  • (20) How useful is the technique for evaluating therapeutic efficacy?