What's the difference between effective and inefficacious?

Effective


Definition:

  • (a.) Having the power to produce an effect or effects; producing a decided or decisive effect; efficient; serviceable; operative; as, an effective force, remedy, speech; the effective men in a regiment.
  • (n.) That which produces a given effect; a cause.
  • (n.) One who is capable of active service.
  • (n.) Specie or coin, as distinguished from paper currency; -- a term used in many parts of Europe.

Example Sentences:

  • (1) Indicators for evaluation and monitoring and outcome measures are described within the context of health service management to describe control measure output in terms of community effectiveness.
  • (2) Previous use of the drug is found in more than 50 per cent of the patients, and it was often followed by a neglected side-effect.
  • (3) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
  • (4) Combinations of maximum amounts of glucagon and the cyclic nucleotide did not produce a greater effect than either agent alone.
  • (5) AEDs may also have differential effects on nighttime sleep.
  • (6) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
  • (7) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
  • (8) Combination therapy was most effective in patients receiving HCTZ prior to enalapril.
  • (9) Age difference did not affect the mean dose-effect response.
  • (10) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
  • (11) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (12) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
  • (13) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
  • (14) Omission of K(+), Ca(++) or Mg(++) had no effect on uptake.
  • (15) Biochemical, immunocytochemical and histochemical methods were used to study the effect of chronic acetazolamide treatment on carbonic anhydrase (CA) isoenzymes in the rat kidney.
  • (16) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
  • (17) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
  • (18) In dogs, cibenzoline given i.v., had no effects on the slow response systems, probably because of sympathetic nervous system intervention since the class 4 effects of cibenzoline appeared after beta-adrenoceptor blockade.
  • (19) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
  • (20) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).

Inefficacious


Definition:

  • (a.) Not efficacious; not having power to produce the effect desired; inadequate; incompetent; inefficient; impotent.

Example Sentences:

  • (1) Treatment was ineffective and stopped in 12 cases (24.5%); the inefficacy was primary in 6 and tachyphylactic in the other 6.
  • (2) of these substances, or -- more accurately -- to a nitrogen inefficacy that they could provoke.
  • (3) Failure are due to overall inefficacy, dropouts from treatment and intolerance.
  • (4) Before 1966, they were mainly due to the choice of inefficacious operations.
  • (5) The case of a 55-year-old woman with a duodenal ulcer developing since 6 months is reported, in whom the surgical indication was early established on the basis of increasing of suffering and inefficacy of the medical treatment.
  • (6) The self-inefficacious stressed subjects were able to withstand increasing amounts of pain stimulation under saline conditions.
  • (7) Thirteen patients had to discontinue the treatment: 6 in the placebo group (inefficacy: 3 cases, anemia: 1 case, epigastric pain: 1 case, rash: 1 case) and 7 cases in the SI group (inefficacy: 2 cases, nauseous: 3 cases, abdominal pain: 1 case, moderate elevation of transaminases: 1 case).
  • (8) -in the second case, poor indications for selective intubation of the left main bronchus by left upper lobectomy initially foreseen, whereas pneumonectomy was necessary, hypoventilation, anoxia, cardiac inefficacy.
  • (9) Partial success with a good clinical result was obtained in 4 cases and there were 7 failures, 6 due to inefficacy of the drug, and 1 because of an extracardiac secondary effect.
  • (10) These results point to a basic inefficacy in the antiestrogen-receptor complex; although it is able to promote early tissue responses characteristic of an estrogen, these cannot be sufficiently maintained.
  • (11) We also have proved that dura mater tubes are inefficacious.
  • (12) The inefficacy of testosterone was attributed to the death of motoneurons before they could re-establish synaptic contact with targets, thereby rendering target-derived trophic substances stimulated by testosterone unable to rescue motoneurons in a timely manner.
  • (13) When hyponatremia develops, it worsens the already present secondary hyperaldosteronism and makes therapy with spironolactone inefficacious.
  • (14) Three out of the remaining nine patients stopped the therapy after 3 months because of inefficacy.
  • (15) During the study the drug had to be discontinued in 32 patients: because of inefficacy in 10, side effects in 11, both in nine, and in two because of unrelated events.
  • (16) There was inefficacy for left cardiac function of normal being.
  • (17) If the same tissues were infected via sensory nerves, following zosteriform spread of the virus the same treatments showed strongly decreased efficacy, or were inefficacious, when started before development of clinical signs in the infected tissues.
  • (18) It is suggested that determination of AI is used as a highly sensitive and operative test for routine monitoring of the patient's intraoperative condition and express diagnosis of inefficacy of anesthesia.
  • (19) Amiodarone may cause a broad variety of arrhythmias that are complicated by their extended duration and difficulty in distinguishing proarrhythmia from simple inefficacy.
  • (20) In patients who did not respond to DPA therapy, not only was the duration of the disease longer, but also previous therapy with other slow acting antirheumatic agents had been stopped because of inefficacy.

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