(1) We have surveyed the rates at which clinicians in the U.K. and Eire withdraw antiepileptic drugs (AEDs) in patients with active epilepsy.
(2) Estimates of the entomological inoculation rate (EIR) ranged from 0.00006 to 0.005 in different samples and vectorial capacity (VC) was 0.0005 for the 1990 sample.
(3) In the fracture group, 2 patients suffered spinal fractures which is noteworthy in that neither were wearing back protectors which as yet are not compulsory safety equipment in Eire.
(4) Their beta-endorphin-like immunoreactivity (beta-EIR) was assayed in plasma before and immediately after running.
(5) The FT, which also increased its price twice last year, had an average daily circulation of 122,286 in the UK and Eire, 61.97% of which were sold at full rate.
(6) To this end the following receptor model system consisting of two receptors was co-expressed in NIH 3T3 cells: a kinase inactive human insulin receptor (HIR K1018A) and a chimeric (EIR) receptor corresponding to the extracellular and transmembrane domains of the human EGF receptor and the cytosolic domain of the human insulin receptor beta subunit.
(7) In contrast to our previous studies on the submersion of scuba divers in a state of neutral buoyancy, neither plasma beta-endorphin-like immunoreactivity (beta-EIR) nor affective feelings were significantly changes in scuba divers by mimicking diving pressures of 2 feet (0.6 m) and 50 feet (15.2 m) for 20 min in a hyperbaric chamber.
(8) Plasma beta-EIR was measured by radioimmunoassay in male scuba divers before and immediately after remaining motionless 10 ft under water in a state of neutral buoyancy.
(9) The gustatory information on early insulin response (EIR), reported by Steffens (1976), is supported by the electrophysiological observations.
(10) In a multi-centre trial of mazindol ('Teronac'), a new anorectic agent unrelated to amphetamine, 274 male and female patients were treated by 53 investigators in Eire.
(11) The result is a joint effort of the original eight participants and invited professors from Italy and Eire as well as from five non-EC countries (Austria, Finland, Norway, Sweden and Switzerland).
(12) Described herein is the preliminary physicochemical characterization of one such regulant, that being the EIR responsible for the Lyt-2+ T cell-dependent expression of FcR epsilon and secretion of an IgE-binding factor (IgE-BF) which can potentiate IgE synthesis; the former activity has been denoted EIRT for its selectivity of action on T cells, and the latter activity has been termed enhancing effector molecule (EEM) for its presumed potentiating influence on IgE antibody synthesis.
(13) The findings of this study demonstrate that normolipidemic patients with CAD may have marked abnormalities in th eir LDL composition and these anomalies are present in both diabetic and nondiabetic patients.
(14) Entomological inoculation rates (EIR) averaged 0.82 infective bites per man per night inside houses in Kisian and 0.65 in Saradidi.
(15) A questionnaire and telephone survey was carried out in April 1991 of all 31 academic departments of general practice in the United Kingdom and Eire; 30 departments responded.
(16) Nine viruses of the Kemerovo serogroup (orbivirus genus; family, Reoviridae) isolated from seabird ticks (Ixodes uriae and Ornithodoros maritimus) from eight different geographical locations (four from Scotland, two from Morocco, one from Eire, one from England, one from the Faeroes Islands) were examined.
(17) A blood sample received from a field case of redwater in Eire caused simultaneous infections of Babesia divergens and Ehrlichia phagocytophila when inoculated into a splenectomised calf.
(18) During the course of these studies, clues as to the physicochemical nature of other EIR activities was obtained.
(19) glucose injection, especially in early insulin release (EIR) and the lesser known post EIR suppression of insulin levels below basal, or acute insulin decrement (AID).
(20) Venipuncture and scuba breathing out of the water did not alter beta-EIR levels.
Hirs
Definition:
(pron.) Hers; theirs. See Here, pron.
Example Sentences:
(1) Anti-synthetic HIRP(957-980) serum HIR-27 was proved to cross-react with HIRP-related proteins in solubilized human placental membranes.
(2) We have investigated insulin responsiveness in relation to insulin sensitivity during sequential hyperglycemic clamping in low insulin responders (LIR), high insulin responders (HIR) and in women with a history of gestational diabetes (GD).
(3) 80% of internalized receptors after 20 min), the internalization in HIR-B cells reaches a maximum (approx.
(4) Human insulin receptor substrate-1 (hIRS-1) cDNAs were cloned from a lambda GT11 expression library using a monoclonal antibody (MAb) produced against a human hepatocellular carcinoma (HCC) cell line (FOCUS).
(5) Within 3 h after exposure to 70 nM insulin, ODC enzyme activity increased approximately 50-fold and mRNA accumulation 3-fold in the HIR 3.5 cells but not in normal fibroblasts.
(6) To further explore the specificity of the IR tyrosine phosphokinase (TPK) domain in IR function, we have altered the human IR (hIR) cDNA to encode truncated insulin-independent TPKs, which are expressed in chinese hamster ovary (CHO) cells as either membrane-anchored or cytosolic proteins.
(7) Glucose disposal and whole body carbohydrate oxidation were markedly lower in NIR and HIR vs. NIS (P less than 0.001 for disposal and oxidation).
(8) Internalization, degradation, and insulin-induced down-regulation of insulin receptors were studied comparatively in transformed Chinese hamster ovary (CHO) cell lines, CHO.T and CHO.IR.ros, respectively expressing either the wild-type human insulin receptor (hIR) or a mutated hybrid receptor in which the transmembrane and cytoplasmic domains of hIR were replaced by corresponding domains of the transforming protein p68gag-ros (v-ros) of avian sarcoma virus UR2.
(9) In conclusion, the HIR delta CT receptor retains intact protein kinase activity in vitro.
(10) Cells expressing 6.4 X 10(3) and 1.25 X 10(6) normal receptors and 2.5 X 10(5) HIR delta CT receptors, as well as control Rat 1 fibroblasts were selected for further analysis.
(11) Highly intensive physical loading suppresses the development of DH and enhances the suppressive effect of staphylococci on SRBC-induced HIR.
(12) Our experiments with the hIR protein have been designed to address a very general question of transmembrane receptor structure and function: What are the roles and interactions of the various deduced structural domains of such molecules in the initiation of the response of cells to extracellular signals?
(13) Mono- and polyauxotrophic mutant of I, II and R-phases by hir, ilv, pro, and mtl markers were obtained by treatment of Sh.
(14) Physical loading of low intensity normalizes staphylococcus-suppressed HIR to SRBC, but produces no effect on staphylococcus-induced DH.
(15) Transfection of normal HIR cDNA produced normal insulin receptors on the plasma membranes in COS 7 cells.
(16) Incubation for 18 hrs with 1 microM insulin resulted in a similar decrease (to approximately 35% of control) of all the hIR mRNA species.
(17) Seven regions of the alpha subunit of human insulin receptor (HIR) were synthesized and examined for their ability to bind radioiodinated insulin.
(18) This cDNA (HIR delta CT), as well as cDNA encoding the complete receptor (HIRc) was transfected into Rat 1 fibroblasts.
(19) To this end the following receptor model system consisting of two receptors was co-expressed in NIH 3T3 cells: a kinase inactive human insulin receptor (HIR K1018A) and a chimeric (EIR) receptor corresponding to the extracellular and transmembrane domains of the human EGF receptor and the cytosolic domain of the human insulin receptor beta subunit.
(20) The resulting virus, named UIR, contains the hIR sequence fused to the 5' portion of the UR2 gag gene coding for p19.