What's the difference between elastin and plastin?
Elastin
Definition:
(n.) A nitrogenous substance, somewhat resembling albumin, which forms the chemical basis of elastic tissue. It is very insoluble in most fluids, but is gradually dissolved when digested with either pepsin or trypsin.
Example Sentences:
(1) The contents of esterified cholesterol and elastin in the aorta were higher in the control group than in the milk-fed group by 28 an 94 per cent, respectively.
(2) After 6 weeks irradiation, the insoluble collagen and elastin were both substantially elevated, as were the activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD).
(3) Similarities between the LIF spectra of atherosclerotic plaque and collagen and normal aorta and elastin were noted.
(4) The data supports the concept of the role of fibrin as the bonding factor in Phase I adherence and implies that collagen, rather than elastin, is primarily responsible for early graft adherence.
(5) Cells obtained from 12-day tissue remained monolayers for 4 to 8 days, after which time portions of the culture contracted into matrix containing chemically definable insoluble elastin and forming desmosine cross-links.
(6) Elastic fibers have been shown to contain two proteins, insoluble elastin and the elastic fiber microfibril, a glycoprotein.
(7) Dermal collagen, elastin, and glycosaminoglycans are altered.
(8) All large arteries contain elastin, collagen, and muscle which can be seen with light microscopy and transmission electron microscopy.
(9) The intracellular biosynthesis of elastin by connective tissue cells, such as smooth muscle cells, involves assembly of the polypeptide chains on the membrane-bound ribosomes, hydroxylation of some prolyl residues to hydroxyproline, and secretion of the polypeptides packaged in Golgi vacuoles.
(10) About 25% of elastin-bound elastase was found to be resistant to the inhibitory effect of alpha 1-proteinase inhibitor.
(11) Its antagonism to calcium is speculated to play a protective role in maintaining the extensibility of elastin.
(12) This accumulated matrix then served as the "substrate" for the exogenously added precursor elastin molecules.
(13) Our examination focused on the organization of elastin and collagen which are the major components of this tunic.
(14) These characteristics demonstrate that arterial smooth muscle cells are capable of synthesizing both soluble and cross-lined elastin in culture.
(15) The activity of lysyl oxidase which catalyzes the initial step of cross-linking of collagen and elastin polypeptides was measured in blood vessels of the hypertensive rat.
(16) Although the diet resulted in significant increases in levels of cholesterol, 25-OH vitamin D3 and calcium in plasma, increased levels of cholesterol and calcium in aortic tissue, and histological evidence of aortic lipid deposition, there were no detectable differences between experimental and control animals in either the rate or the time course of accumulation of total insoluble elastin in the thoracic aorta, or in the rate and time course of synthesis of soluble and insoluble elastin.
(17) Alkali hydrolysates of elastins contained a radioactive peak that was eluted between proline and leucine.
(18) Immunological co-localization of the carboxyl-terminal antibody with insoluble elastin in lung vasculature and parenchyma suggests that intact tropoelastin and not a processed form is incorporated into the elastin fiber.
(19) Adsorbed elastin has been found to be available as a substrate for purified enzymes, as well as for living melanoma cells (A2058 and B16-BL6), c-Ha-ras transformed rat embryo fibroblasts, and human pulmonary macrophages, as demonstrated by the release into the culture medium of lower molecular weight digestion products.
(20) This apparent increase in order occurs at the same temperature as an increase in order in aqueous solution and as a change in the volume expansion coefficient of fibrous elastin.
Plastin
Definition:
(n.) A substance associated with nuclein in cell nuclei, and by some considered as the fundamental substance of the nucleus.
Example Sentences:
(1) Two methods to preserve gastrointestinal tract (GIT) organs and tissues, plastic coating (PC) and plastination (PN), were investigated and compared.
(2) Twelve cadaver achilles tendons were investigated by means of the plastination method.
(3) These candidate genes can be divided into 5 groups: signal transduction proteins (RB1, inhibin alpha, FLT1, and HOX4B), muscle-specific products [myosin light chain, desmin, and nicotinic cholinergic receptor subunits gamma and delta (CHRNG and CHRND)], extracellular matrix proteins (collagen type VI alpha 3 chain, elastin, and fibronectin), transformation-associated products (intestinal alkaline phosphatase and L-plastin), and other genes (esterase D).
(4) Both schedules used plasma activated partial thrombo-plastin time (P-APTT) for adjustment of heparin infusion and aimed at the same therapeutic interval for P-APTT (1.5-2 times the value in normal pooled plasma).
(5) With the present trend in decreased requests for autopsies to be performed, the method of plastination and videotaping coupled with more traditional teaching methods provides a way to expand the information and knowledge that may be obtained from each autopsy in an academic medical center.
(6) In this model natural recombinant hirudins, rHV2 and rHV2-Lys47 injected 5 min before thrombo-plastin totally inhibited thrombosis in the same micrograms range as heparin or natural hirudin extracted from leeches.
(7) Fimbrin is also homologous in sequence with human L-plastin and T-plastin.
(8) A technique of plastination and its application to the preservation of oral pathology teaching specimens is presented.
(9) A microangiography of all femora occurred and after plastination transparent slices were produced.
(10) By means of macroscopic preparations and plastinated crossections of human bodies in the regions of the mons pubis a flat flat-pad (corpus adiposum), covered by connective tissue, was found, which can be demarcated from the subcutaneous adipose tissue.
(11) The finished plastinated specimen is dry to the touch, odorless, and nontoxic, yet it maintains its original shape and, in many cases, is reasonably close in color and consistency.
(12) Fibroblasts transformed in vitro by chemical carcinogens or SV40 virus and tumor-derived cancer cells of fibroblastoid or epithelioid origin usually express plastin and p220, a minor phosphorylated form of plastin.
(13) A morphological study concerning the development and arrangement of the connective tissue in the retrorectal region was performed by investigating 300-700 micron thick sections through fetal pelves, plastinated with the epoxy resin E 12 and cut with a diamond wire-saw.
(14) The modified Spalteholz technique with decalcification of sections and second plastination procedure for the preparation of transparent decalcified bone sections is described.
(15) The endotoxin-stimulated monocytes with their elevated tissue thrombo-plastin activity thus may play an important part in development of the DIC which so often follows septicemia.
(16) We report here that plastin is expressed as one of the most abundant proteins of normal, untransformed lymphocytes.
(17) A new histological method basing on the plastination technique (v. Hagens, Tiedemann, Kriz 1987) has recently been developed and applied to research in human fetal development.
(18) The relative values of different microangiographic techniques have been determined for the first time by means of further developments of the Spalteholz and plastination techniques, because they have provided the possibility of standardizing sections.
(19) Altmejd makes Damien Hirst look like a restrained aesthete, and Gunther von Hagen's plastinated corpses look like a major contribution to science.
(20) Plastinated whole jaws are still readily identifiable from antemortem records.