(1) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
(2) The neuroleptic agents haloperidol, fluphenazine, domperidone, sulpiride and tiapride also antagonized emesis induced by cisplatin but only a proportion of the animals were completely protected and diazepam and prednisolone only reduced the intensity of the response.
(3) Despite excellent control of acute-stage emesis, some patients are still bothered by delayed emesis occurring more than 24 hours after cisplatin administration.
(4) Nine patients suffered emesis in spite of prophylactic therapy and were classified as grade 3.
(5) The efficacy of ipecac syrup in the induction of emesis and safety of its administration was studied in 105 poison-exposed infants 6 through 11 months of age (study subjects) and compared prospectively with 302 poison-exposed infants and children 12 through 35 months of age who served as age controls.
(6) We have compared the ability of drugs to induce chewing and retching or emesis in squirrel monkeys; such studies are not possible in rodents, which do not vomit.
(7) One of these agents, batanopride, produced no severe toxicity at doses that prevented emesis due to chemotherapy in early Phase I trials.
(8) One hundred ten pediatric patients, ages 8 months to 14 yr, admitted for outpatient strabismus surgery were enrolled in a randomized, double-blinded study to compare droperidol and metoclopramide to placebo for the prevention of postoperative emesis.
(9) The aftereffects of home-induced emesis with ipecac syrup were determined by telephone interviews of callers to a poison center.
(10) The treatment given followed the purpose to eliminate the toxic: emesis, gastric washing and in cases of respiratory depression, naloxone was given.
(11) Clinical evidence of pain on injection, myoclonic muscle activity, apnea, nausea, and emesis were documented.
(12) Postoperative emesis, the most common reason for unscheduled admissions, occurred in 23.4% of patients.
(13) Emesis has long been thought to be organized by a 'vomiting centre'; the possibility that this vomiting centre could be the parvocellular reticular formation is reviewed, as is the concept that the 'centre' is larger than an anatomically defined single group of cells.
(14) The 24-h pH monitoring data were within normal ranges in 26 infants (20 controls, 2 babies with emesis, and 4 with RD).
(15) Both findings demonstrate that bismuth subsalicylate can provide antiemetic action and that the decreases in the occurrence of emesis in humans and dogs parallels the decrease in nausea found in humans and the nausea suspected to occur prior to emesis in dogs.
(16) As ICS205930, at high doses, is reported to be a 5-HT4 receptor antagonist it appears likely that activation of 5HT4-receptors contributes to emesis induced by zacopride.
(17) Only in recent years has serious attention been given to the control of chemotherapy-induced emesis (CIE) which is to the patient a most obnoxious side-effect.
(18) Two other sets of experiments suggest that dopaminergic mechanisms play a minor role in radiation-induced emesis in the ferret.
(19) There was no evidence of emesis during the experiments or of overt changes in the appearance of the oral cavity, heart, liver, spleen, kidney, proventriculus, gizzard, and intestines of a random sample of birds killed by carbon dioxide asphyxiation and necropsied.
(20) YM-08050 was more potent than either HPD or CPZ in inhibitory effects on a variety of behaviors such as apomorphine-induced stereotypes behavior and emesis, methamphetamine-induced stereotyped behavior, conditioned avoidance response and open field behavior.
Hematemesis
Definition:
(n.) A vomiting of blood.
Example Sentences:
(1) A patient with abdominal discomfort and hematemesis was found to have lower esophageal inflammation on endoscopy.
(2) A 54 year old white male died three months after hospitalization for hematemesis and melena due to a duodenal ulcer and two monthos after the subsequent onset of progressive ascites and edema.
(3) A case of primary lymphoma of the stomach with massive hematemesis and melena who underwent emergency gastrectomy is reported.
(4) This brief historical data of a patient dying of severe hematemesis as a result of broncho-esophago-aortal fistula in primary pulmonary cavitating carcinoma is presented.
(5) The diagnosis is suggested by the triad of chronic dysphagia, hematemesis, and acute neurologic signs.
(6) Hematemesis and melena may be observed as in the Rendu-Osler disease.
(7) Epistaxis was diagnosed in 10 patients with apparent upper gastrointestinal bleeding, comprising a 0.55% incidence of hematemesis and melena in the population studied.
(8) After the operation, she developed ascites and watery diarrhea, though there was no episode of hematemesis and melena.
(9) Except for one who developed mild hematemesis 3 days after treatment, all patients tolerated the drug very well.
(10) The first patient died within a few minutes of admission from a cataclysmic hematemesis.
(11) A 50-year-old woman was admitted on Feb. 25, 1983, complaining of hematemesis and melena.
(12) In a small number of cases, an aortic false aneurysm or an esophago-bronchial fistula can produce respiratory symptoms without hematemesis, Mediastinal widening on chest X-ray films usually suggests a false aneurysm but it must be differentiated from a mediastinal abscess or a tumor mass.
(13) A case of massive hematemesis from a duodenal ulcer on the third puerperal day is described.
(14) This rarely recognized condition may be an explanation for some cases of cryptic hematemesis.
(15) Hematemesis, melena, shock, vague symptoms, anemia, blood examinations and endoscopic findings are reviewed as signs of recent hemorrhage.
(16) Simultaneously with the hypogastric pain, hypotension, growing circumference of the abdomen and increasing anaemia--without hematemesis or melena--referred to intraabdominal hemorrhage, which was confirmed by diagnostic paracentesis.
(17) A two and a half-year old child is described who presented with signs of portal hypertension (hematemesis, hepatosplenomegaly, ascites).
(18) We reported a 44 year old man with micronodular cirrhosis who eventually died from massive hematemesis and melena.
(19) She died of massive hematemesis and exsanguination on the 14th postoperative day.
(20) Histamine H2 antagonists are widely used in treating patients with hematemesis and melena, despite the lack of reliable evidence of benefit from any of the randomized trials, considered separately.