(n.) The extreme or last point or part of any material thing considered lengthwise (the extremity of breadth being side); hence, extremity, in general; the concluding part; termination; close; limit; as, the end of a field, line, pole, road; the end of a year, of a discourse; put an end to pain; -- opposed to beginning, when used of anything having a first part.
(n.) Point beyond which no procession can be made; conclusion; issue; result, whether successful or otherwise; conclusive event; consequence.
(n.) Termination of being; death; destruction; extermination; also, cause of death or destruction.
(n.) The object aimed at in any effort considered as the close and effect of exertion; ppurpose; intention; aim; as, to labor for private or public ends.
(n.) That which is left; a remnant; a fragment; a scrap; as, odds and ends.
(n.) One of the yarns of the worsted warp in a Brussels carpet.
(v. t.) To bring to an end or conclusion; to finish; to close; to terminate; as, to end a speech.
(v. t.) To form or be at the end of; as, the letter k ends the word back.
(v. t.) To destroy; to put to death.
(v. i.) To come to the ultimate point; to be finished; to come to a close; to cease; to terminate; as, a voyage ends; life ends; winter ends.
Example Sentences:
(1) These included bringing in the A* grade, reducing the number of modules from six to four, and a greater attempt to assess the whole course at the end.
(2) The oral nerve endings of the palate, the buccal mucosa and the periodontal ligament of the cat canine were characterized by the presence of a cellular envelope which is the final form of the Henle sheath.
(3) A full-length cDNA encoding porcine heart aconitase was derived from lambda gt10 recombinant clones and by amplification of the 5' end of the mRNA.
(4) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(5) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
(6) The distance between the end of fic and the start of pabA was 31 base pairs.
(7) Further, at the end of treatment fewer patients had depressive symptoms and the total daily number of hours of wellbeing and normal movement increased.
(8) DI James Faulkner of Great Manchester police said: “The men and women working in the factory have told us that they were subjected to physical and verbal assaults at the hands of their employers and forced to work more than 80-hours before ending up with around £25 for their week’s work.
(9) One rare case of blind-ending branch originating in the upper third of the ureter are described.
(10) Mapping of the cross-link position between U2 and U6 RNAs is consistent with base-pairing between the 5' domain of U2 and the 3' end of U6 RNA.
(11) Anthropometric and nutritional (serum albumin and transferrin) values were normal in both groups both at the beginning and at the end of the treatment period.
(12) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(13) Noradrenaline (NA) was released from sympathetic nerve endings in the tissue by electrical stimulation of the mesenteric nerves or by the indirect sympathomimetic agent tyramine.
(14) The B cell epitopes included regions of transition between the more hydropathic (including the N-terminal end of the F1 and F2 protein) and hydrophilic sequences.
(15) According to the national bank, four Russian banks were operating in Crimea as of the end of April, but only one of them, Rossiisky National Commercial Bank, was widely represented, with 116 branches in the region.
(16) This paper reports, principally, the caries results of the first three surveys of 5, 12 and 5-year-olds undertaken at the end of 1987, 1988 and 1989, respectively.
(17) For dental procedures requiring tracheal intubation, one could perhaps use non-depolarizing muscle relaxants, like pancuronium, with reversal at the end of the procedure.
(18) For retrospective action to be taken, and an FA charge to follow, the decision of the panel must be unanimous.” The match between the sides ended in acrimony and two City red cards.
(19) The number of peripheral blood lymphocytes (PBL) producing IgM (spontaneous and pokeweed mitogen (PWM) stimulated) at the end of a seven day culture period was similar in PBC patients and control subjects while the amount of IgM synthesized (spontaneous and PWM stimulated) during this period was significantly greater in the patient group, implying that the amount of IgM produced per B cell was increased in PBC.
(20) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
Nigh
Definition:
(superl.) Not distant or remote in place or time; near.
(superl.) Not remote in degree, kindred, circumstances, etc.; closely allied; intimate.
(a.) In a situation near in place or time, or in the course of events; near.
(a.) Almost; nearly; as, he was nigh dead.
(v. t. & i.) To draw nigh (to); to approach; to come near.
(prep.) Near to; not remote or distant from.
Example Sentences:
(1) Here was the purveyor of nigh on a third of the nation’s food openly promising a cut that will be barely noticed over time by consumers but will have a positive health impact.
(2) He was like the man with staring eyes who stumbled up and down Oxford Street with a placard declaring the end of the world to be nigh.
(3) But the deeply idiosyncratic Octopuss font on the station sign is a reminder that ‘77 was also the year of Donna Summer’s I Feel Love and Saturday Night Fever: the end of the world may have been nigh, but one corner of Berlin was boogying the night away to uphold western civilisation.
(4) Managing six toddlers is more than a challenge – it's a nigh-on physical impossibility, as my colleague Polly Toynbee pointed out last week.
(5) She was one of the most mature users of Twitter and her Twitter feed was so Tayloresque as to be nigh-on parodic, mixing passionate defences of Jackson with shout-outs to reality TV android Kim Kardashian and the occasional – and necessary – denials that she had re-re-re-re-re-re-re-re-remarried ("Jason is my dearest friend!"
(6) In the era of omnipresent smartphones and tablets, these sacharrine treats are nigh-on inescapable, and as breakthrough hits are guaranteed millions of dollars in revenue (Candy Crush Saga alone generated $1.5bn last year), it's no wonder developers are employing increasingly clever psychological tricks to give their creations a crucial edge.
(7) Sue MacGregor presented the Today programme for nigh on 20 years; Peter Allen and Rhod Sharp have been working at 5 live since day one – 28 March 1994.
(8) Merkel responded that this was nigh-on impossible since it would require changes to the German constitution and around 10 separate legal changes, the sources said.
(9) It is not uncommon for illiberal – in this case, deeply authoritarian – regimes to use a security threat (whether real, imagined, or self-created) as a pretext for singling out alleged ‘traitors’ and cracking down on civil society and individual critics.” Lawyer Khalid Bagirov, who is acting on behalf of all four activists, said the arrests are politically motivated, and added that their acquittal is nigh on “impossible”.
(10) And, once the software is made, it's nigh-on impossible to shut down.
(11) Is the end nigh for the Department for Communities and Local Government?
(12) But just as Oliver Stone has managed to make a boring sequel to Wall Street, despite the real Wall Street's enthralling and nigh-on-cinematic recent wickedness (the inner Freudian torment of boring Shia LaBoeuf's boring character is apparently more interesting to Stone – once the great purveyor of conspiracy theories – than the near-collapse of capitalism), so the makers of the upcoming films about Facebook have missed an obvious trick with their movies.
(13) Now, he thinks, Ireland is playing catchup, and the time is nigh to start imagining a post-religion society.
(14) These patients all complained difficulty falling asleep; all said they usually slept less than 5 hr a nigh and woke up too early in the morning.
(15) It’s embarrassing that Clinton, whose political competence is nigh unparalleled, holds only an uncertain majority over his farcical campaign.
(16) If finding an apartment was difficult – a single woman who could afford to pay her own rent was clearly a hooker in the eyes of most landlords – winning serious work proved to be well nigh impossible.
(17) The need to change one's eating habits in order to treat a certain disease or a metabolic disorder may seem to impose a well nigh impossible task.
(18) Such timings are critical to creditors, and unprecedented January sale discounts were a clear sign that the end was nigh.
(19) Bishop said last week’s attack in London reinforced how, although authorities could track terrorist gangs and keep people under surveillance, it was “nigh on impossible” to keep track of individuals who self-radicalised and acted alone.
(20) The end is nigh is the consensus, but not that nigh.