(n.) The inner layer of the skin or integument of an animal.
(n.) The innermost layer of the blastoderm and the structures derived from it; the hypoblast; the entoblast. See Illust. of Ectoderm.
Example Sentences:
(1) In contrast, F9ACC19, an endodermal cell line derived from F9 cells, synthesizes only minor amounts of lactosaminoglycans and a high proportion of smaller glycopeptides.
(2) Both genes are expressed in the fetal liver, gut, and visceral endoderm of the yolk sac and are repressed shortly after birth in the liver and gut.
(3) Examination of the two types of tissue fragments revealed that IS-treated ICMs almost invariably retained viable endoderm cells whereas MS-isolated ectoderms did so only exceptionally.
(4) LIF inhibits differentiation under several conditions which lead to endodermal and mesodermal cell lineages including skeletal and cardiac muscle.
(5) This epithelial cell was tentatively identified as primitive extraembryonic endoderm by its ultrastructural appearance and its possession of cytokeratin intermediate filaments.
(6) The majority of testicular germ cell tumors in adults are accompanied by neoplastic intratubular germ cells; these cells were uniformly absent in ten pure yolk sac tumors (endodermal sinus tumors) of the testicle in children studied morphologically and immunohistochemically.
(7) After the treatment in toto of the embryos from various species of Anura by cAMP, the number of primordial germ cells (PGC) in genital ridges is strongly reduced; the most part of the PGC are found in the endoderm.
(8) Our experience suggests that the optimal management of patients with primary mediastinal endodermal sinus tumor requires an aggressive multidisciplinary approach guided by the extent of the tumor and the serum tumor marker levels.
(9) The tissues of the endodermal and mesodermal origin were also present in small quantities.
(10) Although the liver first forms as a discrete epithelial bud of endodermal tissue at stage 12-14 (45-53 h after laying), canaliculi were first detected by our antibodies at low levels in 4-day embryos and at high levels in stage 27 (5 days after laying) and later embryos.
(11) The cell cycle time of the gland cells appears to be longer than that of the epithelial cells of the endoderm throughout the animal.
(12) As development proceeded during primitive streak stages, the visceral and parietal endoderm became positively stained.
(13) The F9 cell is a mouse embryonal teratocarcinoma which can be induced to differentiate into visceral endoderm by treatment with retinoic acid (RA).
(14) Multiple hamartoma syndrome, also known as Cowden's disease, is a rare genodermatosis with multiple organ system involvement affecting tissues derived from ectodermal, endodermal, and mesodermal tissue layers.
(15) This finding suggests the identification of a cell population that is analogous to parietal endoderm in some eutherian animals.
(16) We recently showed that yolk sac is involved in the control of metabolism and action of vitamin D in the fetoplacental unit, since its endodermal cells contain a 24-hydroxylase for vitamin D metabolites and the 1,25-dihydroxyvitamin D receptor.
(17) These data thus demonstrate the production and presence of RBP mRNA and TTR mRNA, and the synthesis and secretion of RBP and TTR, by F9 cell embryoid bodies (specifically by visceral endoderm-like cells).
(18) We conclude that yolk-sac-derived teratomas are of endodermal origin because of the fact that the paternal X chromosome is inactivated in the yolk sac endoderm, whereas in the yolk sac mesoderm, as in the embryo, the inactivation is at random.
(19) A particularly interesting proteinase active at alkaline pH values is detected in the trophoblast-endoderm complex.
(20) It is therefore considered that, although there is good evidence that serum AAT is produced by endodermal sinus tumour elements, serum AAT is not a useful monitor of disease activity in these patients, especially when compared with serum AFP, the value of which is well recognized.
Mesoderm
Definition:
(n.) The layer of the blastoderm, between the ectoderm and endoderm; mesoblast. See Illust. of Blastoderm and Ectoderm.
(n.) The middle body layer in some invertebrates.
(n.) The middle layer of tissue in some vegetable structures.
Example Sentences:
(1) Small pieces of anterior and posterior quail wing-bud mesoderm (HH stages 21-23) were placed in in vitro culture for up to 3 days.
(2) Here we report direct measurements of protein kinase C (PKC) activity in uninduced ectoderm, and in neuroectoderm shortly after induction by the involuting mesoderm, in Xenopus laevis embryos.
(3) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(4) However, the pattern in the central nervous system (CNS) and mesoderm is further restricted; the major expression located in the labial neuromere of the CNS and the mesoderm of the first thoracic segment.
(5) The positive reaction for keratin and vimentin confirmed the presence of ectodermal and mesodermal elements respectively in the tumor.
(6) Little deficit in total mesodermal cell number was found, though the entire mesoderm adopted the histological character proper to only some 40% of that in the normal pattern i.e.
(7) LIF inhibits differentiation under several conditions which lead to endodermal and mesodermal cell lineages including skeletal and cardiac muscle.
(8) The histochemical study of the LDH in the Trout embryo during the early organogenesis shows a specific localization in notochord cells, in mesodermic cells of the terminal knob and in some prosencephalic neuroblasts.
(9) This suggests that a factor in the lateral plate mesoderm in addition to the pronephric duct is inhibiting further ventral migration.
(10) While such speculation on how these spatially separated anomalies develop is probably simplistic, the concept of a mesodermal "malformation" spectrum is helpful in reminding the clinician to look for other mesodermal defects when one mesodermally derived defect or sequence is detected.
(11) Cell biological evidence suggests that mesoderm formation and specification of axial positions occur simultaneously.
(12) The tissues of the endodermal and mesodermal origin were also present in small quantities.
(13) There mesodermal expansion proximal to an arrested edge could be compared with that proximal to a moving edge by measuring the amount of vascular elongation occurring in each.
(14) We also assessed the ability of ta2 limb bud mesoderm to respond to a polarizing signal.
(15) Invaginating mesodermal cells of the lateral and ventral parts also form pseudopodia, and are in contact with the blastocoelic wall.
(16) The aim of this study is to test the ability of the intrinsic wing musculature to develop in the absence of somitic mesoderm.
(17) Maintenance of GHox-8 expression by the anterior mesoderm appears to be independent of the presence of the apical ridge.
(18) Multiple hamartoma syndrome, also known as Cowden's disease, is a rare genodermatosis with multiple organ system involvement affecting tissues derived from ectodermal, endodermal, and mesodermal tissue layers.
(19) A unique pattern for a carbohydrate antigen is displayed by cells of the primitive streak; antigenicity is lost with de-epithelialisation and ingression, but is regained in a pericellular distribution on the mesoderm cells that emerge from the primitive streak.
(20) In the mutants twist and snail, which fail to differentiate the ventrally derived mesoderm, mitoses specific to the mesoderm are absent.