(1) Furthermore, comparison of these studies has revealed a differential dose response relationship between the number of graft lymphocytes, protection of engraftment, and induction of acute GVHD.
(2) Engraftment of donor cells was documented by HLA typing of peripheral lymphocytes.
(3) Glucose response to an arginine challenge was initially abnormal in both groups of mice, but was identical to normal controls 4 months after transplantation, showing that engraftment is a gradual process.
(4) Studies in severe combined immunodeficient mice that were engrafted with selected lymphocyte subpopulations show that B cells, and hence anti-Cryptococcus antibodies, are not necessary for the CD4+ T cell-dependent responses that isolate and subsequently destroy this opportunistic pathogen in the lung parenchyma.
(5) Marrow depleted of T cells exhibited reduced engraftment in the recipient fetuses.
(6) Treating bone marrow with MoAbs to myeloid differentiation antigens does not interfere with pluripotential stem cell engraftment.
(7) Prophylaxis by T cell depletion is associated with increased rates of engraftment failure and leukemic relapse.
(8) Posttransplant recovery was uneventful, and engraftment was comparable to that in 4 patients treated with a similar preparative regimen followed by infusion of autologous marrow.
(9) Ten dogs were given a combination of mAb 7.2 pregrafting and MTX after grafting, and 9 had evidence of engraftment.
(10) Three patients who received T-cell-depleted marrow cells from HLA-haploidentical donors failed to engraft and other graft failures were due to inadequate induction dosage.
(11) The in vivo use of an anti-CD11a-LFA-1 antibody as an additional immunosuppressive therapy in HLA-nonidentical BMT may thus promote engraftment and survival with correction of the primary disease in a significant number of patients with life-threatening immunodeficiency and osteopetrosis, but not with Fanconi's anemia.
(12) All four patients achieved quick engraftment, and three of the four patients are alive and well today.
(13) Engraftment has been sustained for one year and the patient is in normal health and has normal in vitro immunological function.
(14) Three of the seven surviving patients have durable engraftment (greater than 230 to greater than 550 days) while four patients have autologous hematopoietic recovery.
(15) All patients who failed to show engraftment or who rejected their bone marrow graft within three weeks had serum inhibitory to normal bone marrow cell culture, but inhibition could not be demonstrated against autologous bone marrow cells in these patients with aplastic anaemia.
(16) This study demonstrated that poor engraftment was a frequent complication of ABMT when early posttransplant cytotoxic therapy was attempted.
(17) The progressive disappearance of this autoreactivity was correlated with the engraftment of Ia-positive cells (monocytes plus B lymphocytes) of donor origin and the achievement of complete immunological reconstitution.
(18) Researchers are currently trying to reduce the RR by intensifying the conditioning regimen or using the graft-versus-leukemia effect of allogeneic T cells, reducing GvHD by the use of monoclonal antibodies, and improving the engraftment by the use of growth factors.
(19) The present work suggests that fetal liver infusion given following induction chemotherapy may increase the remission rate in AML either by temporary engraftment or by accelerating the rate of haematological recovery.
(20) These mice developed an active inflammatory myopathy beginning 15 days after engraftment.
Implant
Definition:
(v. t.) To plant, or infix, for the purpose of growth; to fix deeply; to instill; to inculate; to introduce; as, to implant the seeds of virtue, or the principles of knowledge, in the minds of youth.
Example Sentences:
(1) A spindle cell sarcoma appeared 20 months after implantation of a pellet of 3-methylcholanthrene in the denervated foreleg of an adult frog, Rana pipiens.
(2) During the performance of propulsive waves of the oesophagus the implanted vagus nerve caused clonic to tetanic contractions of the sternohyoid muscle, thus proving the oesophagomotor genesis of the reinnervating nerve fibres.
(3) Membranes of this material were filled with islets of Langerhans and implanted in the peritoneal cavity of rats.
(4) Implantation of the mouse embryo involves the invasion of the secondary trophoblast giant cells of the ectoplacental cone (EPC) into the uterine decidua.
(5) Thus, brain NE levels after training were not predictive of retention performance in amygdala-implanted or -stimulated animals.
(6) Furthermore the limit between hearing aid fitting an cochlear implantation is discussed.
(7) Five days later, the animals were randomly assigned to one of four treatment groups: Group 1 received intracranial implantation of controlled-release polymers containing dexamethasone; Group 2 received intraperitoneal implantation of controlled-release polymers containing dexamethasone; Group 3 received serial intraperitoneal injections of dexamethasone; and Group 4 received sham treatment.
(8) The use of an absorbable material may alleviate potential late complications associated with implantation of nonabsorbable materials.
(9) 11 patients with a postoperative classification of stage D had additional external beam radiation to the pelvic and paraaortic lymph nodes with shielding of the implanted prostatic region.
(10) DES implantation increased the body weight of the ram by 10.4% and caused no significant change in total body water, body ash, or total muscle mass.
(11) The results obtained further knowledge of the anatomy of the nuclei, specifically the areas used for the prosthesis implantation and the underlying tissue.
(12) This technology will provide better information to the surgeon for preoperative diagnosis and planning and for the design of customized implants.
(13) The new trabecular bone closely resembled that typically seen at electrically active implants.
(14) A second group was chronically implanted without electrical stimulation in one leg and implanted with cyclical electrical stimulation applied through the electrode in the other leg.
(15) Resorption of calcium and depositon of inorganic phosphates in the implanted ceramics suggested that ions were being exchanged with the body fluids.
(16) Steroid-treated steers showed a slight decline in synthesis which was significant (P less than 0.05) at week +5 post-implant while amino acid oxidation was significantly lower at weeks +2 (P less than 0.01) and +5 (P less than 0.05) compared with control animals.
(17) During the last 10 years 94% of patients have been normocalcaemic postoperatively, thanks mainly to the re-implantation of autologous parathyroid tissue, preserved by low-temperature storage.
(18) The consequences of proved hypersensitivity in patients with metal-to-plastic prostheses, either present prior to insertion of the prosthesis or evoked by the implant material, are not known.
(19) Electromagnetic interference presented as inhibition and resetting of the demand circuitry of a ventricular-inhibited temporary external pacemaker in a 70-year-old man undergoing surgical implantation of a permanent bipolar pacemaker generator and lead.
(20) Endometriotic implants with good response to Duphaston therapy demonstrated an enhanced autophagic activity within many epithelial cells.