(1) Furthermore, comparison of these studies has revealed a differential dose response relationship between the number of graft lymphocytes, protection of engraftment, and induction of acute GVHD.
(2) Engraftment of donor cells was documented by HLA typing of peripheral lymphocytes.
(3) Glucose response to an arginine challenge was initially abnormal in both groups of mice, but was identical to normal controls 4 months after transplantation, showing that engraftment is a gradual process.
(4) Studies in severe combined immunodeficient mice that were engrafted with selected lymphocyte subpopulations show that B cells, and hence anti-Cryptococcus antibodies, are not necessary for the CD4+ T cell-dependent responses that isolate and subsequently destroy this opportunistic pathogen in the lung parenchyma.
(5) Marrow depleted of T cells exhibited reduced engraftment in the recipient fetuses.
(6) Treating bone marrow with MoAbs to myeloid differentiation antigens does not interfere with pluripotential stem cell engraftment.
(7) Prophylaxis by T cell depletion is associated with increased rates of engraftment failure and leukemic relapse.
(8) Posttransplant recovery was uneventful, and engraftment was comparable to that in 4 patients treated with a similar preparative regimen followed by infusion of autologous marrow.
(9) Ten dogs were given a combination of mAb 7.2 pregrafting and MTX after grafting, and 9 had evidence of engraftment.
(10) Three patients who received T-cell-depleted marrow cells from HLA-haploidentical donors failed to engraft and other graft failures were due to inadequate induction dosage.
(11) The in vivo use of an anti-CD11a-LFA-1 antibody as an additional immunosuppressive therapy in HLA-nonidentical BMT may thus promote engraftment and survival with correction of the primary disease in a significant number of patients with life-threatening immunodeficiency and osteopetrosis, but not with Fanconi's anemia.
(12) All four patients achieved quick engraftment, and three of the four patients are alive and well today.
(13) Engraftment has been sustained for one year and the patient is in normal health and has normal in vitro immunological function.
(14) Three of the seven surviving patients have durable engraftment (greater than 230 to greater than 550 days) while four patients have autologous hematopoietic recovery.
(15) All patients who failed to show engraftment or who rejected their bone marrow graft within three weeks had serum inhibitory to normal bone marrow cell culture, but inhibition could not be demonstrated against autologous bone marrow cells in these patients with aplastic anaemia.
(16) This study demonstrated that poor engraftment was a frequent complication of ABMT when early posttransplant cytotoxic therapy was attempted.
(17) The progressive disappearance of this autoreactivity was correlated with the engraftment of Ia-positive cells (monocytes plus B lymphocytes) of donor origin and the achievement of complete immunological reconstitution.
(18) Researchers are currently trying to reduce the RR by intensifying the conditioning regimen or using the graft-versus-leukemia effect of allogeneic T cells, reducing GvHD by the use of monoclonal antibodies, and improving the engraftment by the use of growth factors.
(19) The present work suggests that fetal liver infusion given following induction chemotherapy may increase the remission rate in AML either by temporary engraftment or by accelerating the rate of haematological recovery.
(20) These mice developed an active inflammatory myopathy beginning 15 days after engraftment.
Propagation
Definition:
(n.) The act of propagating; continuance or multiplication of the kind by generation or successive production; as, the propagation of animals or plants.
(n.) The spreading abroad, or extension, of anything; diffusion; dissemination; as, the propagation of sound; the propagation of the gospel.
Example Sentences:
(1) These studies indicate that at each site of induction during feather morphogenesis, a general pattern is repeated in which an epithelial structure linked by L-CAM is confronted with periodically propagating condensations of cells linked by N-CAM.
(2) The differentiated neuroblastoma cell possesses characteristics of an electrically excitable cell and can generate propagated potential spikes in which Ca2+ is the inward charge carrier.
(3) The ruffles of the sub-marginal cells showed different characteristics, being longer and not propagated successively as were the marginal ruffles.
(4) This method can characterize reliably flavivirus field isolates at the molecular level without extensive virus propagation and molecular cloning, and will be a valuable tool for molecular epidemiological studies.
(5) However the study does not permit to reach any valid conclusions; further elaborate investigations alone could prove the useful role of genetic influence in the propagation of lepromin sensitivity to the subsequent sibs.
(6) This has stemmed from an inadequate understanding of the mechanisms involved in the formation and propagation of this condition.
(7) The E2A mutants were propagated by growth in human cell lines which express an integrated copy of the DBP gene under the control of a dexamethasone-inducible promoter (D. F. Klessig, D. E. Brough, and V. Cleghon, Mol.
(8) Phage H propagated on Yersinia pestis was reported by Molnar and Lawton to be rapidly adsorbed to female but not to male strains of Escherichia coli.
(9) The re-examination of previous data revealed that Caenorhabditis elegans produced 1.8% 24-methyl-23-dehydrocholesterol when propagated in medium containing campesterol.
(10) In 40 subjects the propagation sequence of phasic contractions could be evaluated and were simultaneous in 53%, antegrade in 35%, and retrograde in 11% of the waves.
(11) It is concluded that a number of mechanisms can account for the conduction failure resulting from phospholipase A2, including disruption of sodium channels needed for propagation of regenerative nerve impulses and the depletion of high energy phosphates needed to maintain ionic gradients.
(12) However, a region containing pixels that are perfectly synchronous on average would still yield a finite distribution of calculated Fourier coefficients due to the propagation of stochastic pixel noise into the calculated values.
(13) Following the 1000-kJ but not the 4200-kJ meal, 10 mg cisapride increased total number of contractions, number of propagated contractions, mean amplitude, and area under curve significantly more than placebo.
(14) This phenomenon seems to be due to the generation of surface waves and a corresponding fluid zone into which these waves are also partially propagated.
(15) After 4 months of propagation, this cell line regularly showed 15 to 40% reactive cells.
(16) Because they prevent secondary capsular opacification and anterior vitreous propagation, it appears that such barrier-type implants should be systematically placed.
(17) Propagation and activity level of 18 enzymes catalyzing deamination reactions of dicarboxylic and oxyamino acids and enzymes of amino acid reamination and amino acid N-acyl-derivatives' deacylation have been studied in Klebsiella bacteria.
(18) The reaction studied, thus, appears to be the chain branching and propagation phase of lipoperoxidation.
(19) Study of the growth characteristics of basal cell carcinoma (BCC), a relatively well-organized, slow-growing skin cancer, has been limited because of the lack of methods for propagation of the tumor off the human host.
(20) In cells treated with ion across membranes, tip to base propagation was seen only in the presence of EGTA; when calcium was added the majority of organisms propagated waves from base to tip.