(a.) Indented with small concave curves, as the edge of a bordure, bend, or the like.
Example Sentences:
(1) An ectopic expression assay in Drosophila embryos was used to investigate the roles of pair-rule segmentation genes in the spatial regulation of the segment-polarity gene, engrailed (en).
(2) Engrailed has been suggested to play an important role during development by controlling position-specific characteristics in the CNS of the early embryo.
(3) The engrailed gene is required during embryogenesis of Drosophila melanogaster for normal segmental development and for differentiation of posterior compartments.
(4) Genetic analysis in Drosophila has shown that engrailed (en) plays an important role in segmentation and neurogenesis.
(5) The first pattern of expression is in alternating segments followed by expression in every segment, suggesting that engrailed may be responding to pair-rule segmentation gene products.
(6) By contrast, the homeo box within the engrailed gene diverges substantially and, unlike the other homeo boxes, is interrupted by an intervening sequence.
(7) These results indicate that 1) Engrailed-2 expression is suppressed in the most ventral neural tube owing to induction of the floor plate by the notochord, and 2) that the presence of an underlying notochord is not required for correct rostrocaudal expression, suggesting that multiple pathways act in the patterning of the rudiment of the central nervous system.
(8) The crystal structure of a complex containing the engrailed homeodomain and a duplex DNA site has been determined at 2.8 A resolution and refined to a crystallographic R factor of 24.4%.
(9) This early requirement for engrailed does not appear to be a maternal function, and only genetically engrailed embryos displayed these precellular phenotypes.
(10) No other transcribed regions were found up to 16 kb downstream and 48 kb upstream of the engrailed transcription unit, the portion of the genome to which engrailed mutations have been mapped.
(11) Comparison of amino acid sequences between the entire Xenopus En-2 and the Drosophila engrailed proteins confirms conservation of sequences inside as well as proximal to the homeobox and reveals a region of similarity towards the N terminus.
(12) The Drosophila engrailed gene product (En) is a homeodomain-containing protein that contributes to segmental patterning.
(13) These results are discussed in the context of an autoregulatory model for engrailed regulation.
(14) hh expression in epidermal cells is confined to the posterior compartments and coincides precisely with that of engrailed (en).
(15) An enzyme system that accurately initiates transcription of the engrailed gene has been prepared from Drosophila embryos.
(16) We have examples of patches of hairy cells (where we monitor the effect on fushi tarazu (ftz) expression), even-skipped (monitoring ftz) and ftz (monitoring engrailed and Ultrabithorax).
(17) By examining embryonic expression of the mouse engrailed (En) genes, from 8.0 to 9.5 days postcoitum, we demonstrate that Wnt-1 primarily regulates midbrain development.
(18) This gene, which encodes a transmembrane protein, is initially expressed in a generalized way at blastoderm, but later stops being transcribed in cells expressing the engrailed gene, and even later in cells in the middle of the parasegment.
(19) Autoregulation graduates to wingless independence, but is transient, and is superseded by an engrailed-independent mode of maintenance.
(20) It appears to control morphogenesis by regulating the expression of the segmentation gene engrailed (en), and by autoregulating its own expression (M. Frasch and M.L., in preparation).
Invected
Definition:
(a.) Having a border or outline composed of semicircles with the convexity outward; -- the opposite of engrailed.
Example Sentences:
(1) The structure of the most abundant invected transcript was defined by obtaining the full-length cDNA sequence and by S1 nuclease sensitivity and primer extension studies; a partial sequence of the invected gene was determined; and the developmental profile of invected expression was characterized by Northern analysis and by in situ localization.
(2) The shared region contains a homeo domain and is within the region of engrailed shared with the Drosophila invected gene and the mouse En-1 and En-2 genes.
(3) Speaking to a class of college students in January 2012, he used hateful invective against Jewish people and called Jewish students derogatory names, according to Buzzfeed, which spoke to the professor who invited Cross to his class to teach students about hate groups.
(4) The emails reveal that the researchers shared tactics, encouraged each other and competed for the rudest invective against McIntyre.
(5) But I will not alter them if I am faced with invective rather than debate; in fact, they will become more entrenched.
(6) The invected gene, like the engrailed gene, is expressed in the embryonic and larval cells of the posterior developmental compartments and in the embryonic hindgut, clypeolabrum, and nervous system.
(7) The collision of protests about cuts to legal aid and foreign dignitaries eager to learn from England’s judicial heritage produced contrasting legal blasts of invective and appreciation in Westminster.
(8) Updated at 8.03am BST 5.06am BST Question Time The invective hour opens with condolences.
(9) Wilshere had been fortunate in the first half to avoid what by modern-day standards could easily have been a red-card offence, taking exception to one of Mike Dean’s decisions, aiming a mouthful of invective at the referee and then responding to Marouane Fellaini’s indignation by jutting his forehead into his opponent’s chin.
(10) His purpose is not to change, but to punish, which makes the invective so deeply gratifying.
(11) Like the engrailed gene, the invected gene can encode a protein of approximately 60 kD that contains a homeo box near its carboxyl terminus; indeed, a sequence of 117 amino acids in the carboxy-terminal region of both proteins is almost identical.
(12) Chinese commentators unleashed a stream of nationalist invective on the internet while travel agencies cancelled package tours to Japan.
(13) Two mouse genes, En-1 and En-2, have sequence homology to the engrailed (en) and invected (inv) genes of Drosophila (Joyner et al.
(14) The vgW allele is also the result of a chromosomal inversion, in this case resulting in a gene fusion between vg and the homeobox-containing invected (inv) gene.
(15) When their anti-nationalist invective outweighs their pro-union adulation, you realise that they are not convinced either.
(16) More effectively, every Nazi utterance is in subtitled, guttural, invective-heavy German, which produces the movie's one truly chilling sequence, a mass choir of pretty little Aryan schoolgirls singing a real Nazi hymn that's all racial chauvinism, down with the Jews and death to the untermenschen , as Kristallnacht unfolds in cross-cuts.
(17) The row over foreign secretary David Miliband's attack on the Conservative party chairman, Eric Pickles, for suggesting that Latvians who had joined the Waffen SS volunteer legion were only "conscripts" – following orders – has drawn inevitable invective from Conservatives .
(18) An eagle-eyed spectator caught her blast of invective on camera and it was soon doing the rounds on Twitter.
(19) Whatever else you made of him, when it came to delivering sustained barrages of political invective, you had to salute his indefatigability.
(20) And contemporaries, infuriated by her single-minded and relentless pursuit of her objectives in government, recalled in the cosy glow of nostalgia her huge appetite both for life and for the fight, a woman who delighted in dancing with the enemy at night before spearing him with her invective the next day.