(n.) The act of increasing in size or bulk, real or apparent; the state of being increased; augmentation; further extension; expansion.
(n.) Expansion or extension, as of the powers of the mind; ennoblement, as of the feelings and character; as, an enlargement of views, of knowledge, of affection.
(n.) A setting at large, or being set at large; release from confinement, servitude, or distress; liberty.
(n.) Diffusiveness of speech or writing; expatiation; a wide range of discourse or argument.
Example Sentences:
(1) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
(2) In addition to the aqueduct other associated inner ear anomalies have been identified in 60% of this population including: enlarged vestibule (14); enlarged vestibule and lateral semicircular canal (7); enlarged vestibule and hypoplastic cochlea (4); and hypoplastic cochlea (4).
(3) In high concentrations of antiserum, some of the agglutinated cells of L. h. hertigi were enlarged and showed syncytial characters that included up to five nuclei, two dividing nuclei and five basal bodies associated with a single kinetoplast.
(4) During the 20-year period, the number of children with the enlarged thyroid was found to be 1.5-fold as increased.
(5) Patients with MID, but not those with DAT, exhibited correlations between enlargement of the third and lateral ventricles and severity of cognitive impairment.
(6) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(7) Emergency CT showed evidence of pericardial effusion suggesting hemopericardium, enlargement of the ascending aorta and a peripheral semilunar filling defect which caused a slight deformation of the true channel.
(8) Liver enlargement occurred in the intact male with acetophenetidin (1.0%) but not with the N-butyryl- and thiophenol derivatives fed at 1.0 and 0.50%, respectively.
(9) These cells are characterized by enlarged nuclei which are significantly larger than those in MGCs of the Langhans type.
(10) Restriction of feed intake to 40% of normal attenuated the increases in lung weight and lavage protein concentration in MCTP-treated rats and abolished the right ventricular enlargement but did not affect the increased lavage LDH activity.
(11) In chronic active hepatitis and liver cirrhosis, both carbohydrate antigen 19-9 positive biliary ductular cells and factor VIII-related antigen positive endothelial cells were not only observed in the enlarged portal area but also extended into the parenchyma.
(12) The “100% Australian-made” text on packaging has been enlarged to appeal to customer patriotism.
(13) Hyperprolactinemia, hypogonadotropinism, and subnormal plasma testosterone were found in a 65-year-old patient who had an enlarged sella turcica, complained of fatigue, and addmitted to decreased sexual interest and potency.
(14) The observed clinical findings include scarring of the face and hands (83.7%), hyperpigmentation (65%), hypertrichosis (44.8%), pinched facies (40.1%), painless arthritis (70.2%), small hands (66.6%), sensory shading (60.6%), myotonia (37.9%), cogwheeling (41.9%), enlarged thyroid (34.9%), and enlarged liver (4.8%).
(15) Obstetrician-gynecologists must place lymphocytic adenohypophysitis in the differential diagnosis of pituitary enlargement associated with pregnancy, since treatment is available and the sequelae may be life-threatening.
(16) Some of these vacuoles had remnants of mitochondrial cristae or were enlarged endoplasmic reticulum.
(17) In all dosage groups of the 90-day study special histological methods revealed a dose-dependent increase and enlargement of lysosomes in the epithelia of the proximal renal tubules.
(18) The more enlarged lateral ventricles were ipsilateral with the affected visual pathways.
(19) In the transition from proliferating to hypertrophic cell zones in the growth plate, there is an increased in chondrocyte cell volume and a corresponding decrease in collagen content to allow for cell enlargement.
(20) An enlargement of the epidermal proliferative compartment has been noticed.
Exacerbation
Definition:
(n.) The act rendering more violent or bitter; the state of being exacerbated or intensified in violence or malignity; as, exacerbation of passion.
(n.) A periodical increase of violence in a disease, as in remittent or continious fever; an increased energy of diseased and painful action.
Example Sentences:
(1) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
(2) In patients with acute exacerbations of chronic obstructive pulmonary disease, although either sympathomimetic or anticholinergic therapy provides bronchodilatation, no further benefit could be demonstrated from combination therapy.
(3) We report a case of chronic recurrent polymyositis associated with increasing antibody titers of coxsackievirus A9 in serum during clinical exacerbations.
(4) The data indicate that activated helper T cells are required and sufficient to give rise to the inflammatory infiltrates that are characteristic of the inflammations and exacerbations in human rheumatoid arthritis.
(5) The development of renal insufficiency during enalapril therapy may be exacerbated by concomitant diuretic therapy and should raise the suspicion of underlying transplant renal-artery stenosis.
(6) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(7) The utility of a life charting approach is emphasized in delineating past and present course of illness, considering the relevance of cycling pattern and past treatment efficacy in selection of present pharmacological interventions, and helping to formulate a multifactorial concept of the interplay of biological and psychosocial factors in the evolution or exacerbation of mood disorders.
(8) Endotoxins in plasma were monitored during treatment in 18 patients hospitalised for acute exacerbation of Crohn's disease: systemic endotoxaemia was found on admission in all but one.
(9) Exacerbation of inflammation due to repeated traumatization of the oesophagus wall was accompanied by proliferation of the epithelial layers.
(10) Pyoderma gangrenosum is a poorly understood disease characterized by exacerbations and remissions of morphologically unique skin ulcers.
(11) A complex scheme of prophylaxis of exacerbation and progression of chronic bronchopulmonary diseases in children was developed.
(12) The clinical aspects with remission and exacerbation are discussed.
(13) We designed the present study to evaluate the efficacy and safety of cefaclor in the treatment of acute exacerbations of chronic bronchitis in cigarette smokers.
(14) It was demonstrated that neither enflurane nor halothane exacerbates a pre-existing susceptibility to seizure activity and that both these inhalation anaesthetics are suitable for cases suffering from cerebral convulsive disorders.
(15) We conclude that myoglobinuria, of a degree insufficient to cause renal failure itself, can interact with renal ischemia to significantly exacerbate the renal damage produced.
(16) These lymph node reactions could have likely been a part of the so called early exacerbation.
(17) Hyperglycemia exacerbates neurologic damage in clinical and experimental central nervous system ischemia.
(18) Anticoagulation may exacerbate possible tendencies for an ischemic infarction to become hemorrhagic.
(19) (4) Symptoms are exacerbated by a research ward that is disruptive to the community.
(20) This injury was exacerbated to grade 4 (p less than 0.05) following reperfusion but was almost completely healed 24 h later.