(n.) The "falling sickness," so called because the patient falls suddenly to the ground; a disease characterized by paroxysms (or fits) occurring at interval and attended by sudden loss of consciousness, and convulsive motions of the muscles.
Example Sentences:
(1) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(2) Clonazepam was added to the treatment of patients with poorly controlled epilepsy in a double-blind trial and an open trial.
(3) The fringe of the seizure ("borderland of epilepsy") is briefly delineated.
(4) A total of 1,233 patients with active epilepsy were identified.
(5) Out of 50 epileptics in 31 cases temporal-lobe epilepsy was present, in 15 the seizures and EEG changes were generalized, in 4 cases focal non-temporal-lobe epilepsy was recognized.
(6) Experimental photogenic epilepsy attained by creating GPIE in the EGB with the aid of TT, is proposed as a model for studying the mechanism of epileptogenesis and testing the efficacy of anticonvulsive drugs.
(7) Skeletal muscle mtDNA of three patients with mitochondrial encephalomyopathy, characterized clinically by myoclonic epilepsy and ragged-red fiber (MERRF) syndrome, has been sequenced to determine the underlying molecular defect(s).
(8) Although an unequivocal decision is not possible from existing knowledge, psychomotor or complex partial seizures of temporal lobe epilepsy would be the most tenable diagnosis.
(9) The high positivity ELISA rates for cysticercosis in the CSF and in the patients serum with epilepsy indicate that neurocysticercosis is an important seizure cause in Londrina, PR.
(10) Ectopias of grey matter are recognised foci of epilepsy, but from an epileptological and a clinical viewpoint little attention has been given to these disorders.
(11) We hypothesize that hypofunction of this inhibitory neuron causes overexcitation in the main excitatory pathway which could play a role in epilepsy.
(12) For the purpose of contributing methodologically to experimental research on epilepsy, we investigated whether a difference exists in kindling development between acute and chronic preparations using identical species of animals, kindled brain tissues, stimulus intervals, and intensities.
(13) Management of these patients was difficult and emphasizes the need for specialist expertise for patients with epilepsy and apparent epilepsy.
(14) The medical records of 27 children admitted to the MINCEP Epilepsy Program for evaluation of intractable epilepsy but later shown to have nonepileptic events by EEG with simultaneous video monitoring were reviewed.
(15) Although maternal ingestion of antiepileptic drugs is strongly suspected of causing congenital defects, particularly oral clefts, the effect of epilepsy itself or a combined effect of drug intake and epilepsy have not been excluded as etiological factors.
(16) Bilateral temporal epilepsies involving the limbic system on the one hand, bilateral frontal epilepsies on the other one, and P.M. status which may be paralleled, make these patients more susceptible to acute mental confusions, to acute thymic disorders, to delirious attacks.
(17) The familial association of epilepsy and cleft lip with or without cleft palate (CL (P)) is analyzed assuming both entities share common genetic predisposing factors.
(18) The risk of epilepsy after febrile convulsions is much less than reported in many hospital studies, and if febrile convulsions cause brain damage that leads to later epilepsy this is a rare occurrence.
(19) The results of neuropsychological investigations of 40 patients with severe epilepsy and behaviour disturbances treated by stereotactic methods are presented.
(20) The inhibitory effect of serotonin on the kindling model of epilepsy was investigated in the adult rat.
Epileptic
Definition:
(a.) Pertaining to, affected with, or of the nature of, epilepsy.
(n.) One affected with epilepsy.
(n.) A medicine for the cure of epilepsy.
Example Sentences:
(1) Serum gamma glutamyl transferase (gammaGT) and alkaline phosphatase (ALP) activities have been estimated in 49 epileptic patients taking anticonvulsant drugs.
(2) In this series there were 45 patients (40%) with independent focal interictal EEG epileptic abnormalities over frontobasal cortex (with or without independent spiking over interomedial temporal region).
(3) Out of 50 epileptics in 31 cases temporal-lobe epilepsy was present, in 15 the seizures and EEG changes were generalized, in 4 cases focal non-temporal-lobe epilepsy was recognized.
(4) Among the epileptic patients investigated by the stereotactic E. E. G. (Talairach) whose electrodes were introduced at or around the auditory cortex (Area 41, 42), the topography of the auditory responses by the electrical bipolar stimulation and that of the auditory evoked potential by the bilateral click sound stimulation were studied in relation to the ac--pc line (Talairach).
(5) Lupus anticoagulant associated with thrombocytopenia, thrombosis or recurrent abortions was diagnosed in 2 epileptic patients chronically treated with anticonvulsant drugs.
(6) Eighteen adult epileptic patients under CBZ therapy were evaluated in this single-blind, randomized cross-over study.
(7) The threshold of epileptic spiking varied inversely with the area of cortical damage inflicted by the electrode.
(8) The large degree of inter-dose fluctuation between doses indicates that it is preferable to use pre-dose plasma sodium valproate levels to guide the clinical management of epileptic patients.
(9) These topographies enabled us to observe serial changes in epileptic discharge dynamically by 1 msec.
(10) The additional value of these methods, especially of the intensive monitoring, lies also in the possibility of compiling new knowledge about semiology and electro-clinical correlation of epileptic seizures, possible trigger mechanisms and long-term therapeutic effects.
(11) In epileptic hippocampi, (n = 21) reactive synaptogenesis of mossy fibers into the inner molecular layer of the granule cell dendrites was demonstrated at the light microscopic and electron microscopic levels.
(12) A clinical and electroencephalographic study of 107 neurologically normal children with partial seizures was undertaken to verify the existence and determine the frequency of epileptic syndromes reported in selected populations.
(13) Results show that the SLFIA method is a useful means for the determination of blood concentration of VPA in epileptic patients.
(14) In patients under anti-epileptic therapy it is readily possible for the clinical picture to be concealed, and this may then result in irreversible damage due to the disturbance of metabolism remaining uninfluenced.
(15) Effects of epileptic discharge on the autonomic nervous system are mediated through the cortical, limbic, and hypothalamic systems.
(16) Electroencephalographic activity and extracellular discharges from neurons in deep temporal lobe structures were recorded from fine wire microelectrodes chronically implanted in seven psychomotor epileptic patients for diagnostic localization of seizure foci.
(17) All these symptoms in these six patients disappeared completely or nearly completely after changing to another anti-epileptic drug or reducing the dose.
(18) The single dose pharmacokinetics of orally administered nimodipine (60 mg) were investigated in normal subjects and in two groups of epileptic patients receiving chronic treatment with hepatic microsomal enzyme-inducing anticonvulsants (carbamazepine, phenobarbitone or phenytoin) and sodium valproate, respectively.
(19) An essential complication in the cerebral cortex synaptic structure in the zone with a regular epileptic activity, as well as preservation of quantitative density of synapses near to the control level at epilepsy have been revealed.
(20) It is well established that children of mothers with epilepsy may suffer from facial clefts more frequently than children of non-epileptic mothers.