(a.) Pertaining to, affected with, or of the nature of, epilepsy.
(n.) One affected with epilepsy.
(n.) A medicine for the cure of epilepsy.
Example Sentences:
(1) Serum gamma glutamyl transferase (gammaGT) and alkaline phosphatase (ALP) activities have been estimated in 49 epileptic patients taking anticonvulsant drugs.
(2) In this series there were 45 patients (40%) with independent focal interictal EEG epileptic abnormalities over frontobasal cortex (with or without independent spiking over interomedial temporal region).
(3) Out of 50 epileptics in 31 cases temporal-lobe epilepsy was present, in 15 the seizures and EEG changes were generalized, in 4 cases focal non-temporal-lobe epilepsy was recognized.
(4) Among the epileptic patients investigated by the stereotactic E. E. G. (Talairach) whose electrodes were introduced at or around the auditory cortex (Area 41, 42), the topography of the auditory responses by the electrical bipolar stimulation and that of the auditory evoked potential by the bilateral click sound stimulation were studied in relation to the ac--pc line (Talairach).
(5) Lupus anticoagulant associated with thrombocytopenia, thrombosis or recurrent abortions was diagnosed in 2 epileptic patients chronically treated with anticonvulsant drugs.
(6) Eighteen adult epileptic patients under CBZ therapy were evaluated in this single-blind, randomized cross-over study.
(7) The threshold of epileptic spiking varied inversely with the area of cortical damage inflicted by the electrode.
(8) The large degree of inter-dose fluctuation between doses indicates that it is preferable to use pre-dose plasma sodium valproate levels to guide the clinical management of epileptic patients.
(9) These topographies enabled us to observe serial changes in epileptic discharge dynamically by 1 msec.
(10) The additional value of these methods, especially of the intensive monitoring, lies also in the possibility of compiling new knowledge about semiology and electro-clinical correlation of epileptic seizures, possible trigger mechanisms and long-term therapeutic effects.
(11) In epileptic hippocampi, (n = 21) reactive synaptogenesis of mossy fibers into the inner molecular layer of the granule cell dendrites was demonstrated at the light microscopic and electron microscopic levels.
(12) A clinical and electroencephalographic study of 107 neurologically normal children with partial seizures was undertaken to verify the existence and determine the frequency of epileptic syndromes reported in selected populations.
(13) Results show that the SLFIA method is a useful means for the determination of blood concentration of VPA in epileptic patients.
(14) In patients under anti-epileptic therapy it is readily possible for the clinical picture to be concealed, and this may then result in irreversible damage due to the disturbance of metabolism remaining uninfluenced.
(15) Effects of epileptic discharge on the autonomic nervous system are mediated through the cortical, limbic, and hypothalamic systems.
(16) Electroencephalographic activity and extracellular discharges from neurons in deep temporal lobe structures were recorded from fine wire microelectrodes chronically implanted in seven psychomotor epileptic patients for diagnostic localization of seizure foci.
(17) All these symptoms in these six patients disappeared completely or nearly completely after changing to another anti-epileptic drug or reducing the dose.
(18) The single dose pharmacokinetics of orally administered nimodipine (60 mg) were investigated in normal subjects and in two groups of epileptic patients receiving chronic treatment with hepatic microsomal enzyme-inducing anticonvulsants (carbamazepine, phenobarbitone or phenytoin) and sodium valproate, respectively.
(19) An essential complication in the cerebral cortex synaptic structure in the zone with a regular epileptic activity, as well as preservation of quantitative density of synapses near to the control level at epilepsy have been revealed.
(20) It is well established that children of mothers with epilepsy may suffer from facial clefts more frequently than children of non-epileptic mothers.
Gelastic
Definition:
(a.) Pertaining to laughter; used in laughing.
Example Sentences:
(1) Seven cases of cursive and two cases of gelastic manifestations of epileptic seizures are presented.
(2) Four mentally handicapped patients suffering from gelastic epilepsy were referred to our institution for investigation; three of them also presented with precocious puberty.
(3) The pathological observations carried out in Man are identified with the study of psychomotor epilepsy in the context of "gelastic crises", cataleptic-gelolegic crises "and the pseudo-bulbar syndrome" with crying and spastic laughing.
(4) Three children presented with precocious puberty and two with seizures, one of which was a gelastic (spasmodic or hysteric laughter) type of epilepsy.
(5) The concurrence of gelastic (laughing) seizures, hypothalamic hamartoma and precocious puberty constitutes a well defined epileptic syndrome in children; moreover mental retardation, neuropsychological deterioration and behavioral disorders have been often observed in these patients.
(6) The phenomenon of gelastic epilepsy was first described in 1873, yet fewer than 100 patients with this disorder have been reported on to date.
(7) We described a 9-year-old boy with frontal lobe epilepsy presenting with gelastic seizures.
(8) The cases are discussed in context of current therapeutic conceptions of gelastic epilepsy and central precocious puberty.
(9) When the most prominent ictal symptom in an epileptic seizure is laughing or running the condition has been termed respectively gelastic or cursive epilepsy.
(10) It is likely that gelastic seizure in this case is due to hypothalamic dysfunction.
(11) Attacks mainly consisted of gelastic seizures with comfortable feeling followed by screaming with fear.
(12) The concurrence of gelastic (laughing) seizures and precocious puberty has been reported in 18 patients, including 2 described here.
(13) Gelastic (laughing) epilepsy, relatively uncommon, is usually associated with hypothalamic hamartomas, pituitary tumors, astrocytomas of the mammillary bodies, and dysraphic conditions.
(14) Several variants of TLS can be recognized including atonic akinetic, simple akinetic, atonic, atonic-tonic complex (automatisms), sexual seizures, stress-induced convulsions, and gelastic atonic seizures.
(15) A short history of the condition, clinical and electroencephalographic findings in gelastic epilepsy and causes of pathological laughter are discussed.
(16) Four cases of hypothalamic hamartoma leading to gelastic epilepsy, precocious puberty and behavioural disorders are reported.
(17) The case was a 10-year-old girl, who had been suffering from generalized tonic seizures since age 5, four episodes of alternating hemiplegia since age 6, stunted growth since age 7, and simple partial motor seizures as well as gelastic seizures since age 8.
(18) One episode is presented as gelastic status epilepticus and the clinical and EEG features are reported.
(19) In the present case, the clinical course suggests that the gelastic seizures does not occur by way of the spreading of epileptic discharges to the temporal or hypothalamic region; rather it might occur as a focal symptom of the frontal region.
(20) This paper describes a case of gelastic epilepsy in a middle-aged woman presented in a psychiatric hospital.