(1) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(2) No changes were seen in the levels of serum creatinine and potassium, but episodes of hyperkalemia were more frequent in patients on Epo.
(3) This correlated very well with the EPO concentration in the circulation; EPO levels in the circulation were the same as those of controls at 3 h but increased to six- to sevenfold that of controls by 6 h after cobalt injection.
(4) The relationship between EPO concentration and the changes in Hct during the observation period did not differ between the non-transfusion group and transfusion group.
(5) However, the mean serum EPO concentrations of male and female athletes engaged in a variety of sports were not different from those of sedentary control subjects of both sexes (26.5-35.3 U.ml-1).
(6) Here, we performed in vitro assays of the toxicity of four purified eosinophil granule proteins, namely, MBP, EPO, eosinophil cationic protein (ECP), and eosinophil-derived neurotoxin (EDN), for the mf of Brugia pahangi and Brugia malayi.
(7) Mouse spleen cells rich in erythroid progenitors were washed free of endogenous Epo and then incubated in the absence of Epo.
(8) In Epo containing cultures, the mean number of clusters per burst was lower in PPP than controls, and the percentage of small (less than or equal to 8 clusters) bursts was higher.
(9) The enzyme obtained by this procedure has both the biochemical and the spectral properties of EPO and shows a reasonable degree of purity, as judged by its rz value.
(10) Cloned IW32 and NN10 cells were shown to retain both the ability for erythroid differentiation after incubation with chemical inducers and the ability to produce epo.
(11) The contention that erythropoietin (Epo) affects platelet production was investigated in the rat with recombinant human Epo (rHuEpo).
(12) The important eosinophil granule proteins are major basic protein (MBP), eosinophil cationic protein (ECP), eosinophil derived neurotoxin (EDN) and eosinophil peroxidase (EPO).
(13) In contrast, populations containing BFUe yielded a striking (sixfold for CFUe; 23-fold for e-clusters) expansion of late progenitors in the presence of Epo.
(14) A thirty-seven year old male patient with heavily pretreated metastatic testicular carcinoma received escalating doses of recombinant human erythropoietin (EPO) before and throughout chemotherapy.
(15) The approximately 2.1-kb nucleotide sequence of EPO cDNA corresponds to a prosequence, light chain and heavy chain in that order; similarities to other peroxidases suggest the existence of a multigene family.
(16) SCF interacted with erythropoietin (Epo) and granulocyte colony-stimulating factor (G-CSF) to maintain large numbers of cells as well as to generate a twofold to threefold increase in CFC in the case of Epo, and a 10-fold increase in CFC in the case of G-CSF.
(17) In vitro, ME26 virus specifically induces Epo responsiveness in the interleukin-3-dependent myeloid cell line FDC-P2 by enhancing expression of the Epo receptor (EpoR).
(18) It appears that the transcriptional activation of the rearranged epo gene in IW32 cells has been mediated by a translocation event which has served to bring the epo gene into close juxtaposition to this transcriptionally active gene.
(19) In transgenic mice bled to a hematocrit of 20%, a similar number and distribution of cells contained human EPO mRNA as was found with a 10% hematocrit, but the cells were less heavily labeled, indicating increased EPO production per cell at 10% hematocrit as compared with 20% hematocrit.
(20) Epo treatment, which downregulates c-myb in these cells, induced hemoglobinization to the same degree.
Eros
Definition:
(n.) Love; the god of love; -- by earlier writers represented as one of the first and creative gods, by later writers as the son of Aphrodite, equivalent to the Latin god Cupid.
Example Sentences:
(1) She was a once-in-a-lifetime gal.” A friend of Breaux wrote on Instagram: “God really does give his best angels their wings first.” Breaux was a student at Louisiana State University in Eunice and lived in Lafayette, where she was working at clothing retailer Coco Eros.
(2) She has denounced others for calling him a terrorist, saying he was a freedom fighter in Sri Lanka's non-violent revolutionary student movement Eros .
(3) There were loud cheers from the thousands who gathered around the statue of Eros when the two marches joined up.
(4) Writing in the Guardian , Comfort Ero, Africa director of the International Crisis Group, said: “The insurgents are hampering the work of the independent national electoral commission and have already forced it to halt elections in high-risk areas of Borno, Adamawa and Yobe states.
(5) On the background of a creative psychotherapy with a young man covering the antagonism between Eros and Thanatos creativity is presented as a power not only mediating between destructive and constructive processes but integrating itself into the personal image and sense of life.
(6) Clones resistant to only two drugs (Tet-Chl or Ero-Cli), or sensitive to all drugs were found in cultures of the wild-type strain treated by acridine dyes or ethidium bromide.
(7) In a cross between isogenic plasmids (PI(258)penZ cad x PI(258)penI asa ero), transductants were doubly selected for cadmium and erythromycin resistances.
(8) However, in the hot summer of 1912 an initially chaste and awkward relationship, punctuated with readings of Housman poems and stilted conversations about Eros, swiftly took wing.
(9) The transformation frequencies for the plasmid marker erythromycin resistance (ero) and the chromosomal markers trp, thy, and cyt are of the same order of magnitude, whereas the frequency for the chromosomal marker tyr is approximately one order of magnitude lower.
(10) A strain of C. perfringens type A, isolated from a patient, was found to be resistant to four antibiotics: tetracycline (Tet), chloramphénicol (Chl), erythromycin (Ero) and clindamycin (Cli).
(11) Straight after, they change clothes again to pose for Vanity Fair's upcoming swinging London issue, a session which starts at the ultra-kitsch Eve Club (where Christine Keeler once partied) and ends with them hanging off Eros in the middle of Piccadilly Circus at 9pm.
(12) The friendships based on the concept of pedagogical Eros, as propagated by Gustav Wyneken (1875-1964) in his Wickersdorf Free School Community, are presented as an example.
(13) The electoral commission has stated in guidance that electoral registration officers (EROs) must send out reminders, or even pay a personal visit, telling people to register to vote.
(14) Interestingly, he does not, in Beware of Pity , allude to, or make any real use of, the atmosphere of stifling sexual repression that animates "Eros Matutinus", one of the best chapters of The World of Yesterday , in which Zweig acknowledges there were some very significant aspects of genteel society the world was right to discard.
(15) A further factor shown to be involved is the dialectic tension between eros and thanatos.
(16) This paper examines the aspects of dreaming derived from the principle of Eros, the life instinct as described by Freud in Beyond the Pleasure Principle.
(17) A "complete Eros", or ultimate cure was impossible.
(18) Two types of liposomes, a fluid type, consisting of cholesterol-phosphatidylcholine-phosphatidylserine (5:4:1), and a solid type, consisting of cholesterol-distearoylphosphatidylcholine-dipalmitoylphosphatidylglyc ero l (10:10:1), were used.
(19) The commission strongly recommends that EROs undertake an audit of their registers and write to all households – regardless of whether or not they currently have any registered electors – in good time before the May polls.
(20) Thanatos and Eros seated across from each other over the backgammon board on table four, the onlookers suspending the judgment of ridicule and extending the courtesy of tolerance.