(n.) A diseased condition of rye and other cereals, in which the grains become black, and often spur-shaped. It is caused by a parasitic fungus, Claviceps purpurea.
(n.) The mycelium or spawn of this fungus infecting grains of rye and wheat. It is a powerful remedial agent, and also a dangerous poison, and is used as a means of hastening childbirth, and to arrest bleeding.
(n.) A stub, like soft horn, about the size of a chestnut, situated behind and below the pastern joint.
(n.) See 2d Calcar, 3 (b).
Example Sentences:
(1) Moreover, the ergot drugs were more active in displacing 3H-haloperidol than 3H-dopamine from striatal membranes.
(2) We tested affinities of newly synthesized ergot derivatives to alpha 1- and alpha 2-adrenoceptors, D1- and D2-dopamine receptors, muscarinic acetylcholinoceptors and beta-adrenoceptors using radioligand binding techniques.
(3) The main drugs with specific action on migraine include ergot alkaloids (ergotamine, dihydroergotamine), agonists (sumatriptan) or partial agonists (methysergide) at a specific subtype of 5-HT1-like receptors, beta-adrenoceptor antagonists (propranolol, metoprolol), calcium antagonists (flunarizine) and anti-inflammatory agents (indomethacin).
(4) Eleven women with secondary amenorrhoea and hyperprolactinaemia were treated with lisuride, a new semisynthetic ergot derivative.
(5) The high risk of postabortal complications owing to the defects of the myometrium necessitated the administration of weak uterine drugs, such as ergotal.
(6) This experience suggests that bromocriptine, a derivative of ergot alkaloids, can cause coronary arterial spasm, and subsequent myocardial infarction.
(7) Chromosome examination was made from 12 healthy adult male volunteers by using human lymphocyte cultures twice before, and 8 and 12 weeks after continuous intake of 3 X 1.5 mg Hydergine, an ergot derivative, per day orally.
(8) Effects of ergot alkaloids, nicergoline (NIC), on survival rate, brain water content, local cerebral blood flow (LCBF: 14C-iodoantipyrine) and glucose utilization (LCGU: 14C-2-deoxyglucose) were examined after bilateral carotid artery occlusion (BCAO) in spontaneously hypertensive rats.
(9) Postsynaptic and DA "autoreceptor" agonists [apomorphine, (-) 3-PPP], as well as dopaminergic ergot derivatives (bromocriptine, lergotrile, lisuride) and Sch 23390, substituted for Ly 171555, a partial ergoline which has behavioral effects that are blocked by haloperidol and molindone, but not by either Sch 23390 or serotonin (5-HT) antagonists (ketanserin, pizotifen).
(10) Although the ergot alkaloids (ergots) are useful drugs for the acute treatment of migraine headaches, their mechanism of action remains obscure.
(11) The effect of two recently synthetized dihydrogenated ergot peptide alkaloids has been investigated on the rabbit uterus in situ.
(12) Eleven patients with prolactin-producing pituitary adenomas were treated with the new non-ergot, long-acting dopamine agonist, CV 205-502, for a period of 2-18 months (mean 11 months).
(13) Monoaminergic neuronal systems have been implicated in the mechanisms of action of most ergot derivatives (including those that are clinically useful and those that are "hallucinogenic").
(14) No case of ergotism with such a localization has been previously described in the literature.
(15) This observation and 63 others cases in the litterature call attention to the potential dangers of the ergot derivatives (ergotamine tartrate), even at normally accepted therapeutic doses.
(16) In humans as in animals and in in vitro studies, inhibition of prolactin and LH release induced by ergot drugs are likely due to both an indirect effect via the hypothalamus and to a direct effect on the pituitary cells.
(17) In conclusion, buflomedil is as effective or more effective than dihydrogenated ergot alkaloids in the treatment of senile dementia associated with cerebrovascular insufficiency and could prove a valuable addition to long-term therapy if further studies support the trend shown in this study.
(18) The ergot alkaloids but not BC-105 also exhibited considerable stimulating activity.
(19) If Scammony does contain ergot alkaloids, it is suggested that it will be an excellent source for this material, since the plants cultivation is inexpensive and easy.
(20) Various ergot alkaloids and derivatives were investigated for their interaction with dopaminergic receptors at the level of the rat corpus striatum and nucleus accumbens.
Spurred
Definition:
(imp. & p. p.) of Spur
(a.) Wearing spurs; furnished with a spur or spurs; having shoots like spurs.
(a.) Affected with spur, or ergot; as, spurred rye.
Example Sentences:
(1) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(2) Recognition of this deficiency in our knowledge spurred a belated explosion of research that began with an exploration of the fine structure of the mesothelium.
(3) A 57-year-old man was envenomated via two spur wounds to the right hand from each hind leg of a male platypus.
(4) But it should also be noted that this Spurs team might be the best Spurs team ever, and they've had lots of good teams (including four previous championship teams).
(5) Traction spurs with segmental hypermobility were found more commonly at the L4-5 level in patients whose spines were not fused, particularly women.
(6) She would often say to me, “Don’t go under the house.” And just as her order to not look at the sexy films had spurred me on to do so, I would indeed look under the house.
(7) The uveal protrusion was replaced and a deep corneoscleral block was removed in front of the scleral spur in three cases, and electrocoagulation of the anterior edges of the trabeculectomy fistula was done in other three cases.
(8) Minutes later, Bolton demanded a penalty when Gary Cahill collapsed in the Spurs box after a tackle by Pienaar.
(9) Boris Johnson , the London mayor, got into hot water last week when he praised the value of greed as a spur to progress and controversially suggested some people struggle to get on in life because of their low IQs.
(10) A similar rally in 2007 is widely credited with spurring on Malaysia's opposition movement, which won a landslide victory in the 2008 elections.
(11) As the political pendulum has swung over the decades, these competing archetypes have spurred endless innovations from inflation-linked bonds to free TV licences.
(12) He explains: "Spurs spend a lot of money but only sign players who are 20 or 22 because they're thinking of future sales.
(13) "It was a great debut for Christian," said the Spurs manager.
(14) The council took CPO proceedings after the firm would not agree a price to sell up to Spurs; a judgment is expected next month.
(15) 1.44am BST Heat 19-30 Spurs, 11:00 remaining in 2nd quarter Splitter assists Ginobili who hits a jumper, this Spurs run continues.
(16) The pope, whose foray into diplomacy helped spur negotiations between the US and Cuba , is expected to address the topic in a speech before the UN in New York in September.
(17) Rapid population growth, exacerbating a chronic lack of jobs and economic opportunity, is another powerful spur.
(18) A belated acknowledgement of the damage inflicted by decades of stagnated earnings and inequality have meant pay levels have rightly climbed to prominence, in part spurred by Vermont senator Bernie Sanders who put fair pay at the heart of his campaign attempts to secure the Democratic nomination for president.
(19) Iran Saudi Arabia China Which Chinese Super League club signed former Spurs midfielder Paulinho in 2015?
(20) But Spurs built up a final head of steam and after Gomes punched clear Trippier’s initial cross, a second fell to Son at the near post and he back-heeled the ball past Gomes.