(n.) A diseased condition produced by eating rye affected with the ergot fungus.
Example Sentences:
(1) Moreover, the ergot drugs were more active in displacing 3H-haloperidol than 3H-dopamine from striatal membranes.
(2) We tested affinities of newly synthesized ergot derivatives to alpha 1- and alpha 2-adrenoceptors, D1- and D2-dopamine receptors, muscarinic acetylcholinoceptors and beta-adrenoceptors using radioligand binding techniques.
(3) The main drugs with specific action on migraine include ergot alkaloids (ergotamine, dihydroergotamine), agonists (sumatriptan) or partial agonists (methysergide) at a specific subtype of 5-HT1-like receptors, beta-adrenoceptor antagonists (propranolol, metoprolol), calcium antagonists (flunarizine) and anti-inflammatory agents (indomethacin).
(4) Eleven women with secondary amenorrhoea and hyperprolactinaemia were treated with lisuride, a new semisynthetic ergot derivative.
(5) The high risk of postabortal complications owing to the defects of the myometrium necessitated the administration of weak uterine drugs, such as ergotal.
(6) This experience suggests that bromocriptine, a derivative of ergot alkaloids, can cause coronary arterial spasm, and subsequent myocardial infarction.
(7) Chromosome examination was made from 12 healthy adult male volunteers by using human lymphocyte cultures twice before, and 8 and 12 weeks after continuous intake of 3 X 1.5 mg Hydergine, an ergot derivative, per day orally.
(8) Effects of ergot alkaloids, nicergoline (NIC), on survival rate, brain water content, local cerebral blood flow (LCBF: 14C-iodoantipyrine) and glucose utilization (LCGU: 14C-2-deoxyglucose) were examined after bilateral carotid artery occlusion (BCAO) in spontaneously hypertensive rats.
(9) Postsynaptic and DA "autoreceptor" agonists [apomorphine, (-) 3-PPP], as well as dopaminergic ergot derivatives (bromocriptine, lergotrile, lisuride) and Sch 23390, substituted for Ly 171555, a partial ergoline which has behavioral effects that are blocked by haloperidol and molindone, but not by either Sch 23390 or serotonin (5-HT) antagonists (ketanserin, pizotifen).
(10) Although the ergot alkaloids (ergots) are useful drugs for the acute treatment of migraine headaches, their mechanism of action remains obscure.
(11) The effect of two recently synthetized dihydrogenated ergot peptide alkaloids has been investigated on the rabbit uterus in situ.
(12) Eleven patients with prolactin-producing pituitary adenomas were treated with the new non-ergot, long-acting dopamine agonist, CV 205-502, for a period of 2-18 months (mean 11 months).
(13) Monoaminergic neuronal systems have been implicated in the mechanisms of action of most ergot derivatives (including those that are clinically useful and those that are "hallucinogenic").
(14) No case of ergotism with such a localization has been previously described in the literature.
(15) This observation and 63 others cases in the litterature call attention to the potential dangers of the ergot derivatives (ergotamine tartrate), even at normally accepted therapeutic doses.
(16) In humans as in animals and in in vitro studies, inhibition of prolactin and LH release induced by ergot drugs are likely due to both an indirect effect via the hypothalamus and to a direct effect on the pituitary cells.
(17) In conclusion, buflomedil is as effective or more effective than dihydrogenated ergot alkaloids in the treatment of senile dementia associated with cerebrovascular insufficiency and could prove a valuable addition to long-term therapy if further studies support the trend shown in this study.
(18) The ergot alkaloids but not BC-105 also exhibited considerable stimulating activity.
(19) If Scammony does contain ergot alkaloids, it is suggested that it will be an excellent source for this material, since the plants cultivation is inexpensive and easy.
(20) Various ergot alkaloids and derivatives were investigated for their interaction with dopaminergic receptors at the level of the rat corpus striatum and nucleus accumbens.
Fungus
Definition:
(n.) Any one of the Fungi, a large and very complex group of thallophytes of low organization, -- the molds, mildews, rusts, smuts, mushrooms, toadstools, puff balls, and the allies of each.
(n.) A spongy, morbid growth or granulation in animal bodies, as the proud flesh of wounds.
Example Sentences:
(1) The fate of the inhibited fungus is the subject of this report.
(2) Binding of fibronectin, an extracellular matrix (ECM) protein, to Candida albicans was measured, and adherence of the fungus to immobilized ECM proteins, fibronectin, laminin, types I and IV collagen, and subendothelial ECM was studied.
(3) Cycloheximide and chloramphenicol in combination have a greater effect on yeast cells of Histoplasma capsulatum than on the mycelial phase of this fungus.
(4) Two new isomeric delta-lactones 2 and 3 have been isolated from the marine fungus Helicascus kanaloanus (ATCC 18591).
(5) The manganese peroxidase (MnP), from the lignin-degrading fungus Phanerochaete chrysosporium, an H2O2-dependent heme enzyme, oxidizes a variety of organic compounds but only in the presence of Mn(II).
(6) They induced modifications in particle distribution, a blebbing of particle-free areas and the appearance of lamellar figures on the plasma membrane of fungus cells.
(7) Polyribonucleotide segments, about 60 nucleotides long and consisting of about 95% adenylic acid residues, were isolated from whole cell ribonucleic acid of the deuteromyceteous fungus Trichoderma viride.
(8) There was no significant change in proportion among G (+), G (-) and fungus groups.
(9) The degree of binding differed according to the morphological form of the fungus.
(10) Ion-exchange chromatography showed that this fungus produced multiple molecular forms of LPO.
(11) Subsequent culture is desirable but not always possible.A simple scheme for identifying fungi and fungus-like organisms is presented based on general morphology, staining, and other special characteristics with notes on types of tissue reactions and common pitfalls.
(12) Nevertheless, the finding that MST and CFU studies were loosely correlated in a few strains of mice indicated that the proliferation of the fungus in the kidneys was not always the major cause of death.
(13) Torulopsis glabrata is a yeast-like fungus with increasing importance as an opportunistic human pathogen.
(14) The fungus was demonstrated in the lesions and was isolated from the diseased parts as well as from the air, floor and walls of the breeding cabin.
(15) Morphologic features of Malassezia(M.) furfur in the horny layer from clinical lesions of tinea versicolor were examined by scanning electron microscopy and compared with the appearance of fungus in the horny layer from normal skin and in culture.
(16) medicaginis and eliminated the inhibitory effect showed by this fungus on strain A2 of R. meliloti.
(17) The authors observed maximum simultaneous biosynthesis of antibiotic and pigment in the microphilic fungus with using 48-hour seed mycelium having the specific growth rate of 0.008-0.011 h-1 in an amount of 5-7 per cent (v).
(18) Once the fungus enters the hair cortex just above the hair bulb, it produces myriads of spores that remain trapped and hidden beneath the cuticle for the length of the intact hair.
(19) DNA isolated from the wild-type aflatoxin-producing (Afl+) fungus Aspergillus parasiticus NRRL 5862 was used to construct a cosmid genomic DNA library employing the homologous gene (pyrG) encoding orotidine monophosphate decarboxylase for selection of fungal transformants.
(20) The fungus was not recovered from the brains of normal mice.