(n.) A diseased condition produced by eating rye affected with the ergot fungus.
Example Sentences:
(1) Moreover, the ergot drugs were more active in displacing 3H-haloperidol than 3H-dopamine from striatal membranes.
(2) We tested affinities of newly synthesized ergot derivatives to alpha 1- and alpha 2-adrenoceptors, D1- and D2-dopamine receptors, muscarinic acetylcholinoceptors and beta-adrenoceptors using radioligand binding techniques.
(3) The main drugs with specific action on migraine include ergot alkaloids (ergotamine, dihydroergotamine), agonists (sumatriptan) or partial agonists (methysergide) at a specific subtype of 5-HT1-like receptors, beta-adrenoceptor antagonists (propranolol, metoprolol), calcium antagonists (flunarizine) and anti-inflammatory agents (indomethacin).
(4) Eleven women with secondary amenorrhoea and hyperprolactinaemia were treated with lisuride, a new semisynthetic ergot derivative.
(5) The high risk of postabortal complications owing to the defects of the myometrium necessitated the administration of weak uterine drugs, such as ergotal.
(6) This experience suggests that bromocriptine, a derivative of ergot alkaloids, can cause coronary arterial spasm, and subsequent myocardial infarction.
(7) Chromosome examination was made from 12 healthy adult male volunteers by using human lymphocyte cultures twice before, and 8 and 12 weeks after continuous intake of 3 X 1.5 mg Hydergine, an ergot derivative, per day orally.
(8) Effects of ergot alkaloids, nicergoline (NIC), on survival rate, brain water content, local cerebral blood flow (LCBF: 14C-iodoantipyrine) and glucose utilization (LCGU: 14C-2-deoxyglucose) were examined after bilateral carotid artery occlusion (BCAO) in spontaneously hypertensive rats.
(9) Postsynaptic and DA "autoreceptor" agonists [apomorphine, (-) 3-PPP], as well as dopaminergic ergot derivatives (bromocriptine, lergotrile, lisuride) and Sch 23390, substituted for Ly 171555, a partial ergoline which has behavioral effects that are blocked by haloperidol and molindone, but not by either Sch 23390 or serotonin (5-HT) antagonists (ketanserin, pizotifen).
(10) Although the ergot alkaloids (ergots) are useful drugs for the acute treatment of migraine headaches, their mechanism of action remains obscure.
(11) The effect of two recently synthetized dihydrogenated ergot peptide alkaloids has been investigated on the rabbit uterus in situ.
(12) Eleven patients with prolactin-producing pituitary adenomas were treated with the new non-ergot, long-acting dopamine agonist, CV 205-502, for a period of 2-18 months (mean 11 months).
(13) Monoaminergic neuronal systems have been implicated in the mechanisms of action of most ergot derivatives (including those that are clinically useful and those that are "hallucinogenic").
(14) No case of ergotism with such a localization has been previously described in the literature.
(15) This observation and 63 others cases in the litterature call attention to the potential dangers of the ergot derivatives (ergotamine tartrate), even at normally accepted therapeutic doses.
(16) In humans as in animals and in in vitro studies, inhibition of prolactin and LH release induced by ergot drugs are likely due to both an indirect effect via the hypothalamus and to a direct effect on the pituitary cells.
(17) In conclusion, buflomedil is as effective or more effective than dihydrogenated ergot alkaloids in the treatment of senile dementia associated with cerebrovascular insufficiency and could prove a valuable addition to long-term therapy if further studies support the trend shown in this study.
(18) The ergot alkaloids but not BC-105 also exhibited considerable stimulating activity.
(19) If Scammony does contain ergot alkaloids, it is suggested that it will be an excellent source for this material, since the plants cultivation is inexpensive and easy.
(20) Various ergot alkaloids and derivatives were investigated for their interaction with dopaminergic receptors at the level of the rat corpus striatum and nucleus accumbens.
Logical
Definition:
(a.) Of or pertaining to logic; used in logic; as, logical subtilties.
(a.) According to the rules of logic; as, a logical argument or inference; the reasoning is logical.
(a.) Skilled in logic; versed in the art of thinking and reasoning; as, he is a logical thinker.
Example Sentences:
(1) It would seem logical to select an antihypertensive drug that does not reduce exercise capacity when treating physically active patients with mild and moderate hypertension.
(2) In clinical situations in which complement is damaging, the logical therapy should be, if at all possible, the removal of the activated complement components from the circulation.
(3) Opposition to legal abortion takes magical thinking and a lack of logic | Jessica Valenti Read more The only female Republican candidate for the White House has doubled down on her restrictive position over reproductive rights since a successful debate performance .
(4) The rationale for this assumption seems logical because using all of the available accommodation is not sustainable without discomfort.
(5) He always had a logical approach to his arguments and I would have described him as fair at the time.
(6) Greece sincerely had no intention of clashing with its partners, Varoufakis insisted, but the logic of austerity was such that policies conducted in its embrace could only fail.
(7) The ordered aspect of the genetic code table makes this result a plausible starting point for studies of the origin and evolution of the genetic code: these could include, besides a more refined optimization principle at the logical level, some effects more directly related to the physico-chemical context, and the construction of realistic models incorporating both aspects.
(8) The diagnosis of cervical injuries may be facilitated by following a logical pattern of analysis searching for abnormalities of alignment and anatomy, of bony integrity, of the cartilage or joint spaces, and of the soft tissues.
(9) The end of the cold war and a reshaping of the threats faced by the UK had undermined the logic of nuclear deterrence strategy, he said.
(10) Cameron knew the latter option was not open to him, and had the guts to follow where the implacable logic led.
(11) Results reveal a logical, understandable, and largely adaptive response to intractable seizures and offer little support for the concept of a dysfunctional or pathological interictal personality style.
(12) It imposes a standard of logical reductionism and methodological purity that not only violates the nature of psychoanalytic knowledge, but imposes an invalid standard of verification and scientific confirmation.
(13) A second, un-named Encephalitozoon-like intestinal microsporidia has been identified in five AIDS patients with chronic diarrhea; because it infects lamina propria macrophages, it was logical to investigate its dissemination.
(14) Bypass of surgically inaccessible stenoses or occlusions appears to be a logical technique to prevent future stroke but there is much uncertainty about the clinical indications for surgery and even the natural history of the lesions being bypassed.
(15) The apotheosis of the cockamamie logic surrounding the sale, is the idea that some of the City institutions set to make a killing may own our pensions.
(16) The strict logic is on Sir Menzies's side, but Britain's asymmetric devolution is not unique.
(17) So, logic would dictate that if Greeks are genuinely in favour of reform – and opinion polls have consistently shown wide support for many of the structural changes needed – they would be foolish to give these two parties another chance.
(18) Therefore it would be valuable to use a representation that would allow: knowledge transfer between different systems, users, experts and 'importers' to be able to evaluate the logic, experts to easily input their knowledge and be guided how to use the syntax.
(19) the institutional logic: child's age when admitted, institutional categories.
(20) The implications of these observations in supporting a model of phleomycin amplification proposed previously (6) and their utility in providing a logic for developing a new class of antibiotics are discussed.