(1) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
(2) The overall recoveries of activated ER following chromatography on DEAE-cellulose were significantly lower than the recoveries of the nonactivated ER, 71 and 85%, respectively.
(3) Expression of AR was compared with that of ER and PR as well as with tumour grade and age.
(4) Furthermore, we did not observe correlation between the concentrations of ER and of antiestrogen binding sites (AEBS) in the tumors.
(5) In Stage II patients, chemotherapy has an impact on disease mortality for ER-positive and ER-negative premenopausal women and possibly ER-negative postmenopausal patients.
(6) Plasmids containing the inverted repeat alone bound ER, though less efficiently than did plasmids containing the entire sequence.
(7) It was found that the number of ER in the patients was significantly decreased.
(8) In human breast cancer the proliferating cells appear to differ from those containing estrogen receptors (ER) as shown by studies on isolated cellular subpopulations.
(9) Evidence for Golgi apparatus-associated processing of oligosaccharides in the ER was obtained by lectin-gold cytochemistry revealing the presence of the galactose (beta 1----4)N-acetylglucosamine sequence and sialic acid residues.
(10) Tissues were processed for indirect immunocytochemical localization with specific monoclonal antibodies against estrogen receptor (ER; H222) and progestin receptor (PR; JZB39).
(11) AR and ER mRNA-containing neurons were widely distributed in the rat brain, with the greatest densities of cells in the hypothalamus, and in regions of the telencephalon that provide strong inputs in the medial preoptic and ventromedial nuclei, each of which is thought to play a key role in mediating the hormonal control of copulatory behavior, as well as in the lateral septal nucleus, the medial and cortical nuclei of the amygdala, the amygdalohippocampal area, and the bed nucleus of the stria terminalis.
(12) At saturating concentrations of ER, plasmids bearing one, two, and four EREs in tandem bound approximately one, two, and four dimeric ER molecules, respectively.
(13) Such data provide strong evidence that in this concentration range the growth inhibitory effects of nonsteroidal antioestrogens are mediated by the intracellular ER.
(14) The expression of the ER cDNA in HeLa cells produces a protein that has the same relative molecular mass and binds oestradiol with the same affinity as the MCF-7 ER.
(15) Both methods, which are applicable to paraffin sections, were developed and validated in breast carcinomas with known ER content.
(16) Our results suggest that the synthesis of ER in cervical epithelium can be influenced by underlying stroma.
(17) Despite fulfilling a boyhood wish to play for Milan when he returned to Italy, the striker admitted he erred in taking his career back to Serie A, having had a controversial spell at Internazionale before City recruited him for £17.5m in August 2010.
(18) We have performed a quantitative analysis of steady-state levels of ER-mRNA for 88 untreated, primary breast carcinomas.
(19) Under these conditions, it was shown that resident enzymes of the cis-, medial, and trans-Golgi return to the ER.
(20) In freeze-fracture replicas the ER was seen to consist of both short and long tubules, some of the latter forming anastomoses with each other.