(a.) Belonging to the essence, or that which makes an object, or class of objects, what it is.
(a.) Hence, really existing; existent.
(a.) Important in the highest degree; indispensable to the attainment of an object; indispensably necessary.
(a.) Containing the essence or characteristic portion of a substance, as of a plant; highly rectified; pure; hence, unmixed; as, an essential oil.
(a.) Necessary; indispensable; -- said of those tones which constitute a chord, in distinction from ornamental or passing tones.
(a.) Idiopathic; independent of other diseases.
Example Sentences:
(1) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(2) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(3) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(4) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(5) No significant fatty acid binding by proteins was detected in S. cerevisiae, even when grown on a fatty acid-rich medium, thus indicating that such proteins are not essential to fatty acid metabolism.
(6) The UK's standard position on ICC indictees is to avoid all contact unless "essential".
(7) In spite of important differences in size, chemical composition, polymer density, and configuration, biological macromolecules indeed manifest some of the essential physical-chemical properties of gels.
(8) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(9) Treatment with trypsin gave essentially one radioactive peptide, the active site peptide, of approximately 2300 molecular weight.
(10) We conclude that this enzyme is essentially identical to the native enzyme and should be very useful in the future study of this important hydroxylase.
(11) Thus serum ionized calcium in untreated essential hypertensive patients may predict the blood pressure response to the slow calcium channel blocker verapamil.
(12) The effects of supervised mild aerobic exercise at the work load of the blood lactate threshold for 10 weeks on serum lipids and apolipoproteins were studied in 24 patients with essential hypertension.
(13) No other essential regulatory sequence is located further upstream.
(14) Based on the results of the Community AIM Exploratory Action, further collaborative work is required at EEC level to create an Integrated Health Information Environment (IHE) allowing essentially for integration, modularity and security.
(15) Ovarian vein sampling for androgen was essential in locating this patient's microscopic tumor.
(16) After approximately 20 in vitro passages, Chinese hamster kidney (CHK) cell cultures transformed upon exposure to different strains of SV 40 can show a diploid modal chromosome number of 22 with chromosome counts exclusively or essentially in the diploid range (20-25).
(17) An official from Cafcass, the children and family court advisory service, tried to persuade the child in several interviews, but eventually the official told the court that further persuasion was inappropriate and essentially abusive.
(18) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(19) Essential characteristics of the composite bone cement included a homogeneous and uniform fiber distribution, and a minimal increase in apparent viscosity of the polymerizing cement.
(20) The median blood levels were lower in hyperacidic subjects and higher in hypoacidic patients; the urinary excretion of the digitalis compound showed no essential differences.
Manifold
Definition:
(a.) Various in kind or quality; many in number; numerous; multiplied; complicated.
(a.) Exhibited at divers times or in various ways; -- used to qualify nouns in the singular number.
(n.) A copy of a writing made by the manifold process.
(n.) A cylindrical pipe fitting, having a number of lateral outlets, for connecting one pipe with several others.
(n.) The third stomach of a ruminant animal.
(v. t.) To take copies of by the process of manifold writing; as, to manifold a letter.
Example Sentences:
(1) Combined hypertension treatment with inhibitors of the converting enzyme (ICE) and diuretocs gives manifold advantages, the most important of them is a synergistic action of both drugs resulting in blood pressure decrease and prevention of hypokaliaemia.
(2) It is stressed that the exact anatomical diagnosis requires the examination of every segment which can be performed only by using manifold planes.
(3) An anaerobic sampling manifold withdrew 19 samples of blood during the rest-to-exercise transition; sampling interval was usually 4 s. Blood gas analysis showed that, on average, from rest-to-steady-state exercise, O2 saturation (Svo2) fell from 71 to 41% and mixed venous PCO2 (PvCO2) rose from 42 to 59 Torr.
(4) These induction periods are regarded as the time needed by far-from-equilibrium fluctuations to drive the system into the center manifold.
(5) The apparent Km of the modified enzyme for soluble starch increased manifold, thus implicating the sensitive tryptophan residue in the substrate binding region of the enzyme.
(6) All image vectors were orthonormalized to span a linear manifold.
(7) A manifold for rapid determination of fluoride has been designed that uses a single coil for complex formation and extraction.
(8) Impinger samples were collected from the sampling manifold and analyzed accordingly.
(9) This manifold can be used to validate or calibrate various industrial hygiene analyses such as charcoal and detector tube technology, impinger techniques, respirator cartridge testing, and various survey instruments.
(10) The presentation of SAS may be manifold, and the primary health care teams play a crucial role in the detection of their basic symptoms.
(11) The modification can be made in less than 4 h without the need for any additional parts; the modified manifold requires one-third fewer pump lines and fewer reagents, thus reducing operating costs and simplifying instrument maintenance, while retaining the same precision, speed, low carryover, and linearity of the production model.
(12) The low-field temperature dependence of the MCD of oxidized FdI, which originates in the paramagnetic oxidized [3Fe-4S]1+ cluster, establishes the absence of a significant population of excited electronic states of this cluster up to 60 K. The low-field temperature dependence of the MCD of reduced FdI establishes that the ground-state manifold of the reduced [3Fe-4S]0 cluster possesses S greater than or equal to 2 at both pH 6.0 and 8.3.
(13) The appearance of this disease as generalized vasculitis is conditioned by the manifold clinical symptomatology and thus renders the diagnostics extraordinarily difficult.
(14) After certain modifications had been made in the manifold, satisfactory degrees of accuracy were also obtained for the erythrocyte counts.
(15) Among the manifold immunologic events which take place during parasitic invasions, production of autoantibodies and immune complexes can play a serious role during infections with African and American trypanosomes.
(16) There are manifold specific causes of death characterized by conditions manifest in middle and late life.
(17) It is now customary practice to couple separately metered infusions via a manifold to a common catheter that enters the patient.
(18) The differential diagnoses was manifold because of the traveling habits, the clinical symptomatic and the course of the disease.
(19) Their information must be transduced through binding to membrane receptors, so as to elicit the appropriate biological response from the manifold repertoire of a cell.
(20) The enzyme can be seen as strategically located to play a role in regenerating ATP required for the manifold activities of the synaptic membrane.