(a.) Belonging to the essence, or that which makes an object, or class of objects, what it is.
(a.) Hence, really existing; existent.
(a.) Important in the highest degree; indispensable to the attainment of an object; indispensably necessary.
(a.) Containing the essence or characteristic portion of a substance, as of a plant; highly rectified; pure; hence, unmixed; as, an essential oil.
(a.) Necessary; indispensable; -- said of those tones which constitute a chord, in distinction from ornamental or passing tones.
(a.) Idiopathic; independent of other diseases.
Example Sentences:
(1) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(2) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(3) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(4) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(5) No significant fatty acid binding by proteins was detected in S. cerevisiae, even when grown on a fatty acid-rich medium, thus indicating that such proteins are not essential to fatty acid metabolism.
(6) The UK's standard position on ICC indictees is to avoid all contact unless "essential".
(7) In spite of important differences in size, chemical composition, polymer density, and configuration, biological macromolecules indeed manifest some of the essential physical-chemical properties of gels.
(8) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(9) Treatment with trypsin gave essentially one radioactive peptide, the active site peptide, of approximately 2300 molecular weight.
(10) We conclude that this enzyme is essentially identical to the native enzyme and should be very useful in the future study of this important hydroxylase.
(11) Thus serum ionized calcium in untreated essential hypertensive patients may predict the blood pressure response to the slow calcium channel blocker verapamil.
(12) The effects of supervised mild aerobic exercise at the work load of the blood lactate threshold for 10 weeks on serum lipids and apolipoproteins were studied in 24 patients with essential hypertension.
(13) No other essential regulatory sequence is located further upstream.
(14) Based on the results of the Community AIM Exploratory Action, further collaborative work is required at EEC level to create an Integrated Health Information Environment (IHE) allowing essentially for integration, modularity and security.
(15) Ovarian vein sampling for androgen was essential in locating this patient's microscopic tumor.
(16) After approximately 20 in vitro passages, Chinese hamster kidney (CHK) cell cultures transformed upon exposure to different strains of SV 40 can show a diploid modal chromosome number of 22 with chromosome counts exclusively or essentially in the diploid range (20-25).
(17) An official from Cafcass, the children and family court advisory service, tried to persuade the child in several interviews, but eventually the official told the court that further persuasion was inappropriate and essentially abusive.
(18) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(19) Essential characteristics of the composite bone cement included a homogeneous and uniform fiber distribution, and a minimal increase in apparent viscosity of the polymerizing cement.
(20) The median blood levels were lower in hyperacidic subjects and higher in hypoacidic patients; the urinary excretion of the digitalis compound showed no essential differences.
Necessity
Definition:
(n.) The quality or state of being necessary, unavoidable, or absolutely requisite; inevitableness; indispensableness.
(n.) The condition of being needy or necessitous; pressing need; indigence; want.
(n.) That which is necessary; a necessary; a requisite; something indispensable; -- often in the plural.
(n.) That which makes an act or an event unavoidable; irresistible force; overruling power; compulsion, physical or moral; fate; fatality.
(n.) The negation of freedom in voluntary action; the subjection of all phenomena, whether material or spiritual, to inevitable causation; necessitarianism.
Example Sentences:
(1) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(2) Among 159 patients studied, the severity most frequent was Yahr stage 3 (63%) at first examination, indicating the necessity of earlier diagnosis.
(3) When a product is selected for a patient, consideration should be given to necessity, efficacy, adverse effects, and cost-effectiveness.
(4) Discussion deals with the plurality, specificity, variability, perceived necessity, sufficiency, international utility and career significance of British postgraduate qualifications.
(5) As a result of recent environmental changes in the health care industry, marketing has become a vital necessity for the survival of most hospitals.
(6) There is a necessity for early definitive decision-making in the borderline orthognathic surgery patient and the role of orthodontic camouflage is pointed out.
(7) For Kohut, interpretation depends on the prior establishment of a stable, sustaining transference; human connexion is a lifelong necessity and full understanding an achievable aim.
(8) Management and treatment issues are surveyed, such as the necessity to recognize that in some adolescents violence erupts not from narcissitic rage but from strong wishes for affectionate contact.
(9) A prospective study of the necessity of sedation, or analgesia, or both in total colonoscopy was performed.
(10) The authors report on the casuistry of aorto-coronary by-pass operations they performed between April 1971 and December 1974, discussing the criteria which indicate the necessity of operating, the principles of the operative techniques, and the results obtained.
(11) This case, despite the fatal outcome, emphasises the necessity for a comprehensive approach to the diagnosis of atypical pneumonia, including culture for Legionella, especially in immunocompromised patients.
(12) The sonographic method, with a 97.7% specificity and a negative predictive value of 89.5%, proved to be specific enough to eliminate the necessity of routine catheterization for measuring residual bladder volumes of greater than or equal to 150 cm3, thus decreasing the incidence of some major postoperative complications that can occur due to unnecessary catheterization.
(13) The development of gallstones following this procedure, however, has become more problematic in that further opeation becomes a real necessity.
(14) The necessity of using immunohistochemistry in the diagnosis of sinonasal tumours of fibromatous nature is emphasized.
(15) The experience with 1896 restorative operations on injured nerve trunks shows a necessity to consider the problems of diagnosis, prognosis and choice of the treatment, and especially the results of the nerve suture, not in all patients with nerve injury but only in separate groups being comparable with respect to the kind and severity of the trauma.
(16) Clinico-immunological studies on the use of drugs containing synthetic and biological polymers revealed their high immunomodulating activity and necessity of differentiated use of these drugs with relation to the pathogenetic mechanisms of development of bronchopulmonary diseases as well as mechanisms of their immunological action determined by the molecular mass of polymers as constituents of blood substitutes.
(17) We consider that the rarity of stricture rules out the necessity of any change in management, whether or not erosive oesophagitis is observed at endoscopy.
(18) The discrepancy between the judgement of the insurance company based upon the medical records and the patients complaints also 4-7 years after injury as well as the diversification of therapeutical procedures used in the long term patients career are indicating a necessity of prospective study on cervical spine injury.
(19) Through small and large acts of deprivation and destruction we follow the process: the removal of hope, of dignity, of luxury, of necessity, of self; the reduction of a man to a hoarder of grey slabs of bread and the scrapings of a soup bowl (wonderfully told all this, with a novelist's gift for detail and sometimes very nearly comic surprise), to the confinement of a narrow bed – in which there is "not even any room to be afraid" – with a stranger who doesn't speak your language, to the cruel illogicality of hating a fellow victim of oppression more than you hate the oppressor himself – one torment following another, and even the bleak comfort of thinking you might have touched rock bottom denied you as, when the most immediate cause of a particular stress comes to an end, "you are grievously amazed to see that another one lies behind; and in reality a whole series of others".
(20) In light of the AIDS epidemic and the necessity for safe-sex practices, the topic of caution and prevention is an emerging and critical discourse for the sexual encounter.