(a.) Belonging to the essence, or that which makes an object, or class of objects, what it is.
(a.) Hence, really existing; existent.
(a.) Important in the highest degree; indispensable to the attainment of an object; indispensably necessary.
(a.) Containing the essence or characteristic portion of a substance, as of a plant; highly rectified; pure; hence, unmixed; as, an essential oil.
(a.) Necessary; indispensable; -- said of those tones which constitute a chord, in distinction from ornamental or passing tones.
(a.) Idiopathic; independent of other diseases.
Example Sentences:
(1) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(2) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(3) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(4) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(5) No significant fatty acid binding by proteins was detected in S. cerevisiae, even when grown on a fatty acid-rich medium, thus indicating that such proteins are not essential to fatty acid metabolism.
(6) The UK's standard position on ICC indictees is to avoid all contact unless "essential".
(7) In spite of important differences in size, chemical composition, polymer density, and configuration, biological macromolecules indeed manifest some of the essential physical-chemical properties of gels.
(8) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(9) Treatment with trypsin gave essentially one radioactive peptide, the active site peptide, of approximately 2300 molecular weight.
(10) We conclude that this enzyme is essentially identical to the native enzyme and should be very useful in the future study of this important hydroxylase.
(11) Thus serum ionized calcium in untreated essential hypertensive patients may predict the blood pressure response to the slow calcium channel blocker verapamil.
(12) The effects of supervised mild aerobic exercise at the work load of the blood lactate threshold for 10 weeks on serum lipids and apolipoproteins were studied in 24 patients with essential hypertension.
(13) No other essential regulatory sequence is located further upstream.
(14) Based on the results of the Community AIM Exploratory Action, further collaborative work is required at EEC level to create an Integrated Health Information Environment (IHE) allowing essentially for integration, modularity and security.
(15) Ovarian vein sampling for androgen was essential in locating this patient's microscopic tumor.
(16) After approximately 20 in vitro passages, Chinese hamster kidney (CHK) cell cultures transformed upon exposure to different strains of SV 40 can show a diploid modal chromosome number of 22 with chromosome counts exclusively or essentially in the diploid range (20-25).
(17) An official from Cafcass, the children and family court advisory service, tried to persuade the child in several interviews, but eventually the official told the court that further persuasion was inappropriate and essentially abusive.
(18) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(19) Essential characteristics of the composite bone cement included a homogeneous and uniform fiber distribution, and a minimal increase in apparent viscosity of the polymerizing cement.
(20) The median blood levels were lower in hyperacidic subjects and higher in hypoacidic patients; the urinary excretion of the digitalis compound showed no essential differences.
Obligate
Definition:
(v. t.) To bring or place under obligation, moral or legal; to hold by a constraining motive.
(v. t.) To bind or firmly hold to an act; to compel; to constrain; to bind to any act of duty or courtesy by a formal pledge.
Example Sentences:
(1) However, he has also insisted that North Korea live up to its own commitments, adhere to its international obligations and deal peacefully with its neighbours.
(2) Shorten said any arrangement needed to be consistent with international obligations, with asylum seekers afforded due process and their claims properly assessed.
(3) And this has opened up a loophole for businesses to be morally bankrupt, ignoring the obligations to its workforce because no legal conduct has been established.” Whatever the outcome of the pending lawsuits, it’s unlikely that just one model will work for everybody.
(4) If we’re waiting around for the Democratic version to sail through here, or the Republican version to sail through here, all those victims who are waiting for us to do something will wait for days, months, years, forever and we won’t get anything done.” Senator Bill Nelson, whose home state of Florida is still reeling from the Orlando shooting, said he felt morally obligated to return to his constituents with results.
(5) 45Calcium has been used to compare the kinetics for the transport and bioaccumulation of this regulatory cation in keratinocyte cultures of a kindred with HPS (i.e., one HPS homozygote, one HPS obligate heterozygote, one normal family member, and healthy adult controls).
(6) The department will consider the judgment to see whether it is obliged to rerun the consultation process.
(7) Physicians have an obligation to ensure that parents make a well-considered decision, and to provide them with counsel and support.
(8) As he told us: 'Individual faults and frailties are no excuse to give in and no exemption from the common obligation to give of ourselves.'
(9) Organisms of the genus Bacteroides represent the major group of obligate anaerobes involved in human infections.
(10) Considerations of different ways of obtaining informed consent, determining ways of minimizing harm, and justifications for violating the therapeutic obligation are discussed but found unsatisfactory in many respects.
(11) As commander in chief, I believe that taking care of our veterans and their families is a sacred obligation.
(12) A 20% discount will save the average first-time buyer £43,000 on a £218,000 home (the average cost paid by such buyers), which would leave a revenue shortfall of £8bn from income if current regulatory obligations had been retained on the 200,000 homes.
(13) Justice Hiley later suggested the conduct required by a doctor outside of his profession, as Chapman was describing it, was perhaps a “broad generality” and not specific enough “to create an ethical obligation.” “It’s no broader than the Hippocratic oath,” Chapman said in her reply.
(14) Asked by Marr if he knew if Ashcroft paid tax in this country, Hague said:" I'm sure he fulfils the obligations that were imposed on him at the time he became …" Marr: "Have you asked him?"
(15) These species are all obligately anaerobic, asaccharolytic, and generally nonreactive, and they grow poorly and slowly on media commonly used to isolate anaerobic bacteria.
(16) According to Swedish law, couples who are planning to marry are obliged to publish their address.
(17) In the present report we summarize our data on 144 obligate female carriers.
(18) But whether it arose from religious belief, from a noblesse oblige or from a sense of solidarity, duty in Britain has been, to most people, the foundation of rights rather than their consequence.
(19) No serious side effects were reported and none of the patients was obliged to terminate treatment because of side effects.
(20) This paper argues that although this is true of some types of obligation, including the ones discussed by Professor Kluge, it is by no means true of all.