(a.) To make stable or firm; to fix immovably or firmly; to set (a thing) in a place and make it stable there; to settle; to confirm.
(a.) To appoint or constitute for permanence, as officers, laws, regulations, etc.; to enact; to ordain.
(a.) To originate and secure the permanent existence of; to found; to institute; to create and regulate; -- said of a colony, a state, or other institutions.
(a.) To secure public recognition in favor of; to prove and cause to be accepted as true; as, to establish a fact, usage, principle, opinion, doctrine, etc.
(a.) To set up in business; to place advantageously in a fixed condition; -- used reflexively; as, he established himself in a place; the enemy established themselves in the citadel.
Example Sentences:
(1) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
(2) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
(3) The role of whole Mycobacteria, mycobacterial cell walls and waxes D as immunostimulants was well established many years ago.
(4) A backbench policy advisory group will be established to develop ideas.
(5) Since it was established, it has stoked controversy about contemporary art, though in recent years it has been more notable for its lack of sensationalism.
(6) Nasotracheal intubation has been well established as a method for maintaining an artificial airway in children.
(7) Using multiple regression, a linear correlation was established between the cardiac index and the arterial-venous pH and PCO2 differences throughout shock and resuscitation (r2 = .91).
(8) Developing seminiferous tubules and interstitial cells were first seen on day 26, and were well established one day later.
(9) In three of these patients this was associated with the presence of a previously well established abscess cavity.
(10) To identify the NHE-1 protein and to establish its cellular and subcellular localization in the rabbit kidney, we prepared antibodies to a NHE-1 fusion protein.
(11) The structures of 1 and 2 were established mainly on the basis of nmr spectroscopic data.
(12) It was established that nonsurgical methods of transplantation with laboratory animals were less time-consuming and were more readily applicable.
(13) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(14) We found that, although controlled release delivery of ddC inhibited de novo FeLV-FAIDS replication and delayed onset of viremia when therapy was discontinued (after 3 weeks), an equivalent incidence and level of viremia were established rapidly in both ddC-treated and control cats.
(15) After several months, a temporal discrimination was well established, as shown by maximum suppression toward the end of the signal period.
(16) An experimental model was established in the ewe allowing one to predict with accuracy an antral follicle that coincidentally would either undergo ovulation (6-8 mm diameter) or atresia (3-4 mm diameter) following synchronization of luteal regression and the onset of the gonadotropin surge.
(17) In 8 of 32 patients (25%) the diagnosis was established only at autopsy.
(18) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(19) We previously established that the binding constant (Ka) of this receptor site for the chemically synthesized model AGE, 2-(2-furoyl)-4(5)-(2-furanyl)-1H- imidazole-butyric acid (FFI-BA), on cells of the mouse macrophagelike cell line RAW 264.7 is identical to that for AGE proteins.
(20) Neil Blessitt Bristol • We need to establish what the legal position is with regard to the establishment by the government of a private company co-owned by the Department of Health and the French firm Sopra Steria.
Generate
Definition:
(v. t.) To beget; to procreate; to propagate; to produce (a being similar to the parent); to engender; as, every animal generates its own species.
(v. t.) To cause to be; to bring into life.
(v. t.) To originate, especially by a vital or chemical process; to produce; to cause.
(v. t.) To trace out, as a line, figure, or solid, by the motion of a point or a magnitude of inferior order.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) Structure assignment of the isomeric immonium ions 5 and 6, generated via FAB from N-isobutyl glycine and N-methyl valine, can be achieved by their collision induced dissociation characteristics.
(4) Richard Bull Woodbridge, Suffolk • Why does Britain need Chinese money to build a new atomic generator ( Letters , 20 October)?
(5) These membrane perturbation effects not observed with bleomycin-iron in the presence of a hydroxyl radical scavenger, dimethyl thiourea, or a chelating agent, desferrioxamine, were correlated with the ability of the complex to generate highly reactive oxygen species.
(6) It was also found that lipocortin I and ONO-RS-082, but not neomycin, facilitated the generation of GIF-producing T cells.
(7) Reactive metabolites which suppress splenic humoral immune responses are thought to be generated within the spleen rather than in distant tissues.
(8) The results indicate that OA-bearing macrophages primed T cells and generated helper T cells, whereas the culture of normal lymphocytes with soluble OA in the absence of macrophages generated suppressor T cells.
(9) Discrimination errors were used to generate a matrix of interletter and interpattern similarities.
(10) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
(11) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(12) This result suggests that tryptophan-86 may be importantly involved in the generation of the product excited state during aequorin bioluminescence.
(13) Midtrimester abortion by the dilatation and evacuation (D&E) method has generated controversy among health care providers; many authorities insist that this procedure should be performed only by a small group of experts.
(14) The transmission of alcoholism and its effects are thereby lessened for future generations of children of alcoholics.
(15) Furthermore, high-density catalase-positive--but not catalase-negative--E. coli can survive and multiply in the presence of competitive, peroxide-generating streptococci.
(16) We are the generation who saw the war,, who ate bread received with ration cards.
(17) These results suggest that CD4+ protective T cells generated by immunization with vBCG are characterized by the ability to produce IFN-gamma after stimulation with specific Ag.
(18) The alpha-ketoglutarate generated is reduced with glutamate dehydrogenase and NADH.
(19) We investigated the possible contribution made by oropharyngeal microfloral fermentation of ingested carbohydrate to the generation of the early, transient exhaled breath hydrogen rise seen after carbohydrate ingestion.
(20) Extensive proliferation has been shown to accompany the de novo generation of LAK cytotoxicity.