(n.) An ethereal salt, or compound ether, consisting of an organic radical united with the residue of any oxygen acid, organic or inorganic; thus the natural fats are esters of glycerin and the fatty acids, oleic, etc.
Example Sentences:
(1) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(2) Preincubation of human neutrophils with recombinant tumor necrosis factor alpha has previously been shown by us to enhance superoxide production of neutrophils in response to the chemotactic peptide formyl-methionyl-leucyl-phenylalanine, and the phorbol ester, phorbol myristate acetate.
(3) Tumor promoting phorbol esters (1-1000 nM) could also inhibit PGE2 stimulated cAMP production dose dependently.
(4) These products were identified to be epimers of 5,12(S)-dihydroxy-eicosatetraenoic acid methyl ester (5,12(S)-diHETE-Me) and epimers of 11,12-diHETE-Me.
(5) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(6) The immunodetectable PKC level in hypothyroid liver was elevated 7.7-fold, whereas the phorbol-ester binding capacity and the immunodetectable alpha-PKC level were increased 2.4- and 2.6-fold, respectively.
(7) The presence of a previously unreported dipeptide transport mechanism within blood leukocytes and the selective enrichment of the granule enzyme, DPPI, within cytotoxic effector cells of lymphoid or myeloid lineage appear to afford a unique mechanism for the targeting of immunotherapeutic reagents composed of simple dipeptide esters or amides.
(8) Incubation of membrane with DL-Hcys alone (5 X 10(-5) M), the combination of both Ad (5 X 10(-5)) and DL-Hcys (5 X 10(-5)), or S-adenosyl-L-homocysteine (SAH) (1 X 10(-6)) strongly decreased the methyl ester formation.
(9) To this purpose, the formation of DHT has been measured in rat glial cell cultures after different time of exposure to TPA, 4 alpha-Ph, an active and an inactive phorbol ester respectively, and 8-Br-cAMP.
(10) Insulin incubation of plasma membranes pretreated with protease inhibitors (leupeptin, phenylmethylsulfonylfluoride) or with exogenous trypsin, but not chymotrypsin substrates (esters of arginine and tyrosine) yields an inactive supernatant on PDH.
(11) Lymphocyte stimulation by phorbol ester for a short time induces c-fos and c-myc expression, but has no effect on [3H]thymidine incorporation.
(12) The cryptoxanthin esters varied from 5 to 10% of the total carotenoids in Valencia orange juice concentrates and from 10 to 15% of the total carotenoids in Navel orange juice concentrates.
(13) Early in the regression process, cholesterol esters are reduced at least partly by hydrolysis to yield cholesterol, some of which may crystallize and inhibit rapid regression.
(14) The kinetics of the luminescent signal with the different luciferin esters varied significantly, indicating possible differences in the rates of uptake, breakdown and enzyme inhibition.
(15) In comparison to rat pancreas, [D-Phe6]BN-(6-13)ethyl ester, Ac-GRP-(20-26)ethyl ester, [D-Phe6,Cpa14, psi 13-14]BN-(6-14), [Leu14, psi 13-14]BN, and [Leu14, psi 9,10]BN had a 10,000-, 2,940-, 1,425-, 122-, and 4-fold, respectively, weaker affinity for BN receptors.
(16) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(17) To determine whether the triadimefon-induced hyperactivity is due to an action on CNS catecholaminergic systems, we evaluated the effects of combined treatment of triadimefon with either the tyrosine hydroxylase inhibitor d,l-alpha-methyl-p-tyrosine methyl ester HCl (alpha MPT) or the amine depletor reserpine.
(18) Growth of C. albicans in the presence of AGE affected the yeast lipid in a number of ways: the total lipid content was decreased; garlic-grown yeasts had a higher level of phosphatidylserines and a lower level of phosphatidylcholines; in addition to free sterols and sterol esters, C. albicans accumulated esterified steryl glycosides; the concentration of palmitic acid (16:0) and oleic acid (18:1) increased and that of linoleic acid (18:2) and linolenic acid (18:3) decreased.
(19) In comparison with native counterparts, the in vitro-formed LDL2 and HDL + VHDL were characterized by lower levels of triglyceride and cholesterol ester and higher levels of free cholesterol and lipid phosphorus.
(20) Several histidine derivatives are not susceptible to the enzyme but do inhibit the enzyme activity competitively; the most effective inhibitors are L-histidine methyl ester (Ki = 3.66 mM) and beta-imidazole lactic acid (Ki = 3.84 mM).
Fester
Definition:
(n.) To generate pus; to become imflamed and suppurate; as, a sore or a wound festers.
(n.) To be inflamed; to grow virulent, or malignant; to grow in intensity; to rankle.
(v. t.) To cause to fester or rankle.
(n.) A small sore which becomes inflamed and discharges corrupt matter; a pustule.
(n.) A festering or rankling.
Example Sentences:
(1) The lesson for the international community, fatigued or bored by competing stories of Middle Eastern carnage, is that problems that are left to fester only get worse – and always take a terrible human toll.
(2) Such a commission should begin work immediately, so that anger and suspicion does not fester while Libyans wait 18 months for a constitutionally elected government.
(3) We are in our prime, still strong, living full and interesting lives, not stuck at home festering in a candlewick dressing gown (OK, sometimes, but only when it’s cold and dark outside).
(4) Yet just because Mr Hague’s ideas have exploded on the launchpad, it does not mean that the issues they address can be left to fester.
(5) So there should be no lifting of sanctions as long as the conflict in Ukraine festers on.
(6) Few of these plans have yet been agreed, allowing rumours and fears to fester – and when they do emerge, the government can expect no backing, not even from their own MPs and councillors.
(7) These approaches enable the children to find ways to externalise the trauma, rather than letting it fester like an internal time bomb.
(8) Depression and anxiety fester when children are not supported.
(9) A sense of victimhood festers among even relatively advantaged white men, as the rancorously popular candidacy of Donald Trump confirms.
(10) Politically, authorities don't have much reason to; it just reopens a big, festering wound."
(11) Resist the urge to stroke her brows as her doubts about him begin to fester.
(12) It seems that "festering" is OK if there is a political motivation.
(13) It remains one of Europe's most volatile flashpoints, driving away trade and allowing distrust to fester in its place.
(14) He noted the ambivalence of the world towards US military actions, but argued that failed states such as Somalia and Afghanistan could not be left to fester.
(15) The sectarian enmity that festered during the war years has been reignited by the war in Syria, which pitches a Sunni majority against an Alawite minority with links to Shia Islam .
(16) This festering resentment came to a head on 23 January 1974, when the two men ended up wrestling on the floor of an ABC studio in New York, five days before their second fight at Madison Square Garden.
(17) It festered after Blair resiled from an understanding that he would step down during a second term.
(18) There is festering local anger about culture secretary Andy Burnham's refusal to intervene, and things look increasingly grim, though the proposals' outraged opponents have one last hope: allegations that the obligatory consultation was so half-cocked that it should be subject to judicial review.
(19) One politician labelled Yau a “cancer cell” while a pro-China scholar referred to her as a “festering pustule” .
(20) But behind all the headlines about the €85bn bailout, there was another festering sore – the banks themselves were nearly bust.