(n.) An ethereal salt, or compound ether, consisting of an organic radical united with the residue of any oxygen acid, organic or inorganic; thus the natural fats are esters of glycerin and the fatty acids, oleic, etc.
Example Sentences:
(1) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(2) Preincubation of human neutrophils with recombinant tumor necrosis factor alpha has previously been shown by us to enhance superoxide production of neutrophils in response to the chemotactic peptide formyl-methionyl-leucyl-phenylalanine, and the phorbol ester, phorbol myristate acetate.
(3) Tumor promoting phorbol esters (1-1000 nM) could also inhibit PGE2 stimulated cAMP production dose dependently.
(4) These products were identified to be epimers of 5,12(S)-dihydroxy-eicosatetraenoic acid methyl ester (5,12(S)-diHETE-Me) and epimers of 11,12-diHETE-Me.
(5) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(6) The immunodetectable PKC level in hypothyroid liver was elevated 7.7-fold, whereas the phorbol-ester binding capacity and the immunodetectable alpha-PKC level were increased 2.4- and 2.6-fold, respectively.
(7) The presence of a previously unreported dipeptide transport mechanism within blood leukocytes and the selective enrichment of the granule enzyme, DPPI, within cytotoxic effector cells of lymphoid or myeloid lineage appear to afford a unique mechanism for the targeting of immunotherapeutic reagents composed of simple dipeptide esters or amides.
(8) Incubation of membrane with DL-Hcys alone (5 X 10(-5) M), the combination of both Ad (5 X 10(-5)) and DL-Hcys (5 X 10(-5)), or S-adenosyl-L-homocysteine (SAH) (1 X 10(-6)) strongly decreased the methyl ester formation.
(9) To this purpose, the formation of DHT has been measured in rat glial cell cultures after different time of exposure to TPA, 4 alpha-Ph, an active and an inactive phorbol ester respectively, and 8-Br-cAMP.
(10) Insulin incubation of plasma membranes pretreated with protease inhibitors (leupeptin, phenylmethylsulfonylfluoride) or with exogenous trypsin, but not chymotrypsin substrates (esters of arginine and tyrosine) yields an inactive supernatant on PDH.
(11) Lymphocyte stimulation by phorbol ester for a short time induces c-fos and c-myc expression, but has no effect on [3H]thymidine incorporation.
(12) The cryptoxanthin esters varied from 5 to 10% of the total carotenoids in Valencia orange juice concentrates and from 10 to 15% of the total carotenoids in Navel orange juice concentrates.
(13) Early in the regression process, cholesterol esters are reduced at least partly by hydrolysis to yield cholesterol, some of which may crystallize and inhibit rapid regression.
(14) The kinetics of the luminescent signal with the different luciferin esters varied significantly, indicating possible differences in the rates of uptake, breakdown and enzyme inhibition.
(15) In comparison to rat pancreas, [D-Phe6]BN-(6-13)ethyl ester, Ac-GRP-(20-26)ethyl ester, [D-Phe6,Cpa14, psi 13-14]BN-(6-14), [Leu14, psi 13-14]BN, and [Leu14, psi 9,10]BN had a 10,000-, 2,940-, 1,425-, 122-, and 4-fold, respectively, weaker affinity for BN receptors.
(16) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(17) To determine whether the triadimefon-induced hyperactivity is due to an action on CNS catecholaminergic systems, we evaluated the effects of combined treatment of triadimefon with either the tyrosine hydroxylase inhibitor d,l-alpha-methyl-p-tyrosine methyl ester HCl (alpha MPT) or the amine depletor reserpine.
(18) Growth of C. albicans in the presence of AGE affected the yeast lipid in a number of ways: the total lipid content was decreased; garlic-grown yeasts had a higher level of phosphatidylserines and a lower level of phosphatidylcholines; in addition to free sterols and sterol esters, C. albicans accumulated esterified steryl glycosides; the concentration of palmitic acid (16:0) and oleic acid (18:1) increased and that of linoleic acid (18:2) and linolenic acid (18:3) decreased.
(19) In comparison with native counterparts, the in vitro-formed LDL2 and HDL + VHDL were characterized by lower levels of triglyceride and cholesterol ester and higher levels of free cholesterol and lipid phosphorus.
(20) Several histidine derivatives are not susceptible to the enzyme but do inhibit the enzyme activity competitively; the most effective inhibitors are L-histidine methyl ester (Ki = 3.66 mM) and beta-imidazole lactic acid (Ki = 3.84 mM).
Pester
Definition:
(v. t.) To trouble; to disturb; to annoy; to harass with petty vexations.
(v. t.) To crowd together in an annoying way; to overcrowd; to infest.
Example Sentences:
(1) The creation of Albion’s second goal was more artful, even if it started with Özil being pestered into surrendering possession near halfway.
(2) It was Tim, an archivist from Warners whom I had been pestering for years about trying to track down some long-lost film footage.
(3) They should not pressure children or pester parents to buy products, and promotional offers should be used with a "due sense of responsibility".
(4) The allegations are sure to concern many parents whose children are pestering them to buy the extensive range of Cars 2 toys launched to coincide with the movie, which hit UK cinema screens in July.
(5) Professional irritant Kenny Miller wins a corner down the right, with some incessant pestering.
(6) For a year I have been pestered with: "X has got Facebook.
(7) He kept pestering her, phoning and phoning and phoning her."
(8) But while the Christians are still pestering God, the end-of-daysers awaiting Armageddon, and the Aryan brothers proving the least convincing imaginable argument for the superiority of their race, things have changed quite drastically in porn, which has been even more vulnerable than cinema, TV or music to the predations of the internet.
(9) Kala-azar (KA), an enigmatic disease has resurged in India since 1970's after about a lull of 20 years, displaying its pestering nature.
(10) The band became pally with him and pestered for a support slot when his Black Pus project (another great name) came to town.
(11) After a bit of good-natured pestering, she agrees to sell all of us one drink so we can discuss the heady topic of race in America while slightly intoxicated.
(12) Artists don't stand next to their artwork in galleries pestering the public to part with their pound coins.
(13) For now he is determined to stick with his work in the building industry, despite his workmates pestering him for the odd Victoria sponge or carrot cake.
(14) Nine hours working as an exterminator takes a physical toll on the 45-year-old , who didn’t go to college, makes $33,000 a year, and relies on a steady swarm of pests to pester people in his 90% rural county.
(15) The new boss, Paul Pester, whose £1.6m outstanding bonuses from Lloyds are to be transferred to TSB, is also aiming for growth in current accounts, where it has only 4.2% market share despite having some 6% of high street branches.
(16) There are some innovative ideas about, he says, on ways of teaching children in school to wash their hands – in the hope that they will then go home and pester their parents to do the same.
(17) Joleon Lescott, who endured a torrid debut for Villa, and Micah Richards were pestered into errors in the opening minutes and the latter was especially relieved that Danny Drinkwater’s shot from 25 yards flew over the bar.
(18) Paul Pester, chief executive of TSB, said the branches that were closing were within 500 metres of another TSB branch and were part of the estate it inherited when it was carved out of Lloyds Banking Group last year.
(19) Pester said the bank had achieved its target of winning more than 6% of all new current accounts and those being switched between banks.
(20) Pester added that, of the 631 branches TSB started with, there were 15 locations where two or three branches were “within spitting distance of each other”.