(n.) Any compound of ethyl of a binary type; as, potassium ethide.
Example Sentences:
Methide
Definition:
(n.) A binary compound of methyl with some element; as, aluminium methide, Al2(CH3)6.
Example Sentences:
(1) The coupled dienone-phenol re-arrangement and keto-enol tautomerism of this quinone methide produce the observed 3,4-dihydroxybenzaldehyde.
(2) The cytostatic activity of several triterpenequinone methides isolated from Rzedowskia tolantonguensis and Maytenus horrida (Celastraceae) was evaluated against HeLa cell cultures.
(3) The white colour of the cyst wall of the metacercaria of Microphallus sp., even in the presence of dihydroxy phenol and phenoloxidase, is due to proteins generated through a possible quinone methide interaction.
(4) N-methylation of the imidazole ring(s) produces structures which can form extended quinone methides.
(5) Under anaerobic conditions and with NADPH as a reducing agent, daunomycin is reduced in the presence of spinach ferredoxin: NADP+ oxidoreductase as the enzyme catalyst to its hydroquinone, from which intramolecular elimination of the C-7 glycoside proceeds to provide a quinone methide intermediate.
(6) As with mitomycin C, reduction and quinone methide formation are necessary for alkylation by the title quinone.
(7) Using a purified o-quinone isomerase from the larval cuticle of Sacrophaga bullata and mushroom tyrosinase, we now demonstrate that transiently formed N-acetyldopamine quinone methide from N-acetyldopamine can be trapped by methanol to produce beta-methoxy N-acetyldopamine.
(8) The structure of the adducts is in conformity with the generation and reactions of dehydro NADA quinone methide (or its radical).
(9) These arise by covalent trapping by solvent of a quinone methide intermediate, obtained by rearrangement of the mitomycin c hydroquinone.
(10) Oxidation of the pi system leads to the quinol, 2,6-di-t-butyl-4-hydroxy-4-methyl-2,5-cyclohexadienone, the quinone, 2,6-di-t-butyl-4-benzoquinone, and the quinone methide, 2,6-di-t-butyl-4-methylene-2,5-cyclohexadienone.
(11) Our results suggest that eugenol is oxidized by cytochrome P450 to a reactive quinone methide intermediate which can then covalently modify protein or conjugate with glutathione.
(12) Accordingly, desaturase enzyme preparation contained both o-diphenoloxidase activity and NADA quinone:NADA quinone methide isomerase activity.
(13) Resolution of the NADA desaturase system on Benzamidine Sepharose and Sephacryl S-200 columns yielded the above-mentioned quinone isomerase and NADA quinone methide:dehydro NADA isomerase.
(14) Mouse liver and lung microsomes generate the two quinone methides, and evidence was obtained that both metabolites also are formed in vivo.
(15) It may exist as an equilibrium mixture of the p-quinone and o-quinone methides in solution.
(16) The second process is assigned to reaction of the quinone methide with water yielding hydroxylated product(s) which may subsequently react with remaining quinonoid cation or quinone methide to give dimeric product(s) with broad absorption centreing in the 550 nm region detected 0.5 s after the pulse.
(17) These three conjugates were identical with the products obtained from the chemical reaction of synthetic eugenol quinone methide and glutathione.
(18) Insoluble cuticle-bound enzyme(s) of Manduca sexta pharate pupae, which is known to convert N-acetyldopamine to N-acetylnorepinephrine through the intermediate formation of quinone methide, also converted exogenously supplied N-acetyldopamine quinone to N-acetylnorepinephrine.
(19) The bioactivation of the pulmonary toxin 3-methylindole has been postulated to proceed via the formation of an imine methide.
(20) Mushroom tyrosinase and the recently identified, 4-alkyl-o-benzoquinone: 2-hydroxy-p-quinone methide isomerase were used to investigate the mechanism of biosynthesis of papiliochrome II pigment found in the yellow scales of the papilionid butterflies.