(v. t.) To render more violent or bitter; to irriate; to exasperate; to imbitter, as passions or disease.
Example Sentences:
(1) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
(2) In patients with acute exacerbations of chronic obstructive pulmonary disease, although either sympathomimetic or anticholinergic therapy provides bronchodilatation, no further benefit could be demonstrated from combination therapy.
(3) We report a case of chronic recurrent polymyositis associated with increasing antibody titers of coxsackievirus A9 in serum during clinical exacerbations.
(4) The data indicate that activated helper T cells are required and sufficient to give rise to the inflammatory infiltrates that are characteristic of the inflammations and exacerbations in human rheumatoid arthritis.
(5) The development of renal insufficiency during enalapril therapy may be exacerbated by concomitant diuretic therapy and should raise the suspicion of underlying transplant renal-artery stenosis.
(6) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(7) The utility of a life charting approach is emphasized in delineating past and present course of illness, considering the relevance of cycling pattern and past treatment efficacy in selection of present pharmacological interventions, and helping to formulate a multifactorial concept of the interplay of biological and psychosocial factors in the evolution or exacerbation of mood disorders.
(8) Endotoxins in plasma were monitored during treatment in 18 patients hospitalised for acute exacerbation of Crohn's disease: systemic endotoxaemia was found on admission in all but one.
(9) Exacerbation of inflammation due to repeated traumatization of the oesophagus wall was accompanied by proliferation of the epithelial layers.
(10) Pyoderma gangrenosum is a poorly understood disease characterized by exacerbations and remissions of morphologically unique skin ulcers.
(11) A complex scheme of prophylaxis of exacerbation and progression of chronic bronchopulmonary diseases in children was developed.
(12) The clinical aspects with remission and exacerbation are discussed.
(13) We designed the present study to evaluate the efficacy and safety of cefaclor in the treatment of acute exacerbations of chronic bronchitis in cigarette smokers.
(14) It was demonstrated that neither enflurane nor halothane exacerbates a pre-existing susceptibility to seizure activity and that both these inhalation anaesthetics are suitable for cases suffering from cerebral convulsive disorders.
(15) We conclude that myoglobinuria, of a degree insufficient to cause renal failure itself, can interact with renal ischemia to significantly exacerbate the renal damage produced.
(16) These lymph node reactions could have likely been a part of the so called early exacerbation.
(17) Hyperglycemia exacerbates neurologic damage in clinical and experimental central nervous system ischemia.
(18) Anticoagulation may exacerbate possible tendencies for an ischemic infarction to become hemorrhagic.
(19) (4) Symptoms are exacerbated by a research ward that is disruptive to the community.
(20) This injury was exacerbated to grade 4 (p less than 0.05) following reperfusion but was almost completely healed 24 h later.
Optimist
Definition:
(n.) One who holds the opinion that all events are ordered for the best.
(n.) One who looks on the bright side of things, or takes hopeful views; -- opposed to pessimist.
Example Sentences:
(1) Johnson and Campion are optimistic that marriage equality will win out, and soon.
(2) Two years ago, the Intergovernmental Panel on Climate Change declared Egypt's Nile Delta to be among the top three areas on the planet most vulnerable to a rise in sea levels, and even the most optimistic predictions of global temperature increase will still displace millions of Egyptians from one of the most densely populated regions on earth.
(3) Even under the most optimistic scenarios, shale gas is projected to meet just 10% of European gas demand by 2030.
(4) I have the optimist's world view of America as a tolerant place, where anyone can grow up to be the President.
(5) He says there are many optimistic tales to tell – migrant families, he says, are helping to drive up standards in local schools – but such stories tend to get lost in an online world that has precious little interest in them.
(6) All I wanted to know was that this was not a hereditary disease – partly, I suppose, because I was so young and carefree and optimistic.
(7) I was optimistic that I could leave behind my reputation as the nerdy one of my friends.
(8) The new Poles are generally optimistic and open-minded, believing their destiny to be in their own hands, that Poland shouldn't be prisoner to its past and that the future waxes bright for their country.
(9) The Bank of England has a record of being over-optimistic about Britain's prospects and in its latest assessment of the economy once again cut its growth forecast.
(10) Excessively optimistic judgements of driving competency and accident risk have often been implicated in the disproportionate involvement of young males in traffic crashes.
(11) I would urge her to follow the example of Elizabeth I, who, on appointing as her chief minister Sir William Cecil, said of him: “This opinion I have of you: that whatever you know my personal opinion to be, you will give me advice that is best for the realm.” Valerie Crews Beckenham, Kent • Another immensely qualified person loses their job for not being optimistic enough about Brexit.
(12) English speakers are the least optimistic about the chances of avoiding dangerous climate change Out of more than 6,000 self-selecting respondents, many expressed dismay at the slow pace of political action on climate change.
(13) Both brothers had been in optimistic mood earlier in the day.
(14) Arsène Wenger said he hopes the midfielder will return in four weeks and, “if all goes well, three”, but the estimate is believed to be optimistic.
(15) The optimists, not the least of whom are the British, believe that the summit is a starting point on which to build.
(16) "We'd have preferred that, in addition to these increases, we had seen our market share grow overall this quarter but we are optimistic that some of the sector's major rebranding campaigns and marketing initiatives will start taking effect in results this year."
(17) The most optimistic of them sees a fall by 2030, but this would require huge investments in renewable energy as well as financial and technical support from overseas.
(18) Jints fans, suddenly optimistic about their postseason chances, forgot how bad their team was over the fortnight - today they are being reminded.
(19) Reagan's youthful hero was FDR – another optimist, albeit a far steelier one – who turned the federal government into the agent of recovery from the Great Depression and of victory in World War II.
(20) A recent National Audit Office study pinpointed these precisely: the DWP’s approach, it finds, is too rigid; its policy assumptions tend to be untested and over-optimistic; strategically, it fails to anticipate uncertainty (specifically, the possibility of failure); it neglects to monitor progress, so does not notice when things go wrong until far too late.