(a.) Oppressive or unreasonably severe in making demands or requiring the exact fulfillment of obligations; harsh; severe.
Example Sentences:
(1) Meanwhile Bradley Beal has developed into a dangerous second option and complementary sidekick in exactly the same way that Dion Waiters hasn't for the Cleveland Cavaliers.
(2) Furthermore, the backing away from any specific yield targets is exactly the lack of clarity that the FX market will not like."
(3) If it works anyone can do this exactly as we have done.” The sudden release follows weeks of visual clues left on the Radiohead frontman’s Twitter and Tumblr.
(4) She was clearly elected on a pledge not to cut school funding and that’s exactly what is happening,” Corbyn said.
(5) Hamilton said it was uncanny to find themselves in another desperate emergency situation almost exactly one year on.
(6) He missed the start of the season while rehabbing from last season's ankle injury, played exactly six games with the Los Angeles Lakers before getting hurt again and even if he's healthy he may still sit the game out .
(7) Johnson said the move would save businesses £350m from not having to meet the more exacting standards, which will now only have to be met by buses.
(8) These experiments represent the first occasion that the sequence specificity of a DNA damaging agent, which causes only double-strand breaks, has been determined to the exact base-pair in intact cells.
(9) The structural region contains serines, threonines, and cysteines at exactly the positions required to give mature nisin by a series of post-translational modifications involving dehydration of serines and threonines to dehydro forms, and cross-linking with cysteine residues.
(10) We propose that exact definitions must be given for the auxiliary enzymes in the recommendations of standard determinations for enzyme activities.
(11) Early diagnosis and exact resuscitation are the two most important aspects of a plan of treatment which anticipates the need for early surgery.
(12) But now, that's exactly what he tried to do … and it didn't work," he said.
(13) Concentrations of DLIS were detectable in significantly more (58.3%) of the 12 CHF patients (group A) who were not receiving digoxin than in the 22 normal volunteers tested (13.6%) (P less than 0.05 by both chi-square and Fisher's exact test).
(14) One of them got a gold medal in medicine, for being top of the year, but they dropped out for exactly these reasons.” These are not alarmist stories being spread by campaigners.
(15) But she has struggled – quite awkwardly – to articulate her evolution on same-sex marriage, and has left environmental activists wondering what her exact energy policy is.
(16) The surgeon must have an exact idea of this canal before undertaking operation for plastics of the hernial defect.
(17) The exact timing of the introduction of the glycopeptide antibiotics teicoplanin and vancomycin in the management of the febrile neutropenic patient continues to be controversial.
(18) While some might deride the deliberate mainstream branding and design, saying it panders to convention, this is exactly what Hannah feels her community needs.
(19) The predicted yeast enzyme contains at least four potential membrane-spanning regions and several shorter hydrophobic regions that align exactly with similar sequences in the rat liver protein.
(20) If, for the PWC 170 will be utilized, two steps with heart-rates of greater than 140 on the lower and 160 to 170 on the higher step, the PWC 170 seems to be exactly sufficient for estimating the maximal physical working capacity for routine testing of healthy young people.
Extracting
Definition:
(p. pr. & vb. n.) of Extract
Example Sentences:
(1) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(2) A phytochemical investigation of an ethanolic extract of the whole plant of Echites hirsuta (Apocynaceae) resulted in the isolation and identification of the flavonoids naringenin, aromadendrin (dihydrokaempferol), and kaempferol; the coumarin fraxetin; the triterpene ursolic acid; and the sterol glycoside sitosteryl glucoside.
(3) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(4) Consensual but rationally weak criteria devised to extract inferences of causality from such results confirm the generic inadequacy of epidemiology in this area, and are unable to provide definitive scientific support to the perceived mandate for public health action.
(5) The specific activities of extracts from cells grown under phototrophic and aerobic conditions were similar and not affected by the concentration of iron in the growth media.
(6) Recovery of CV-3988 from plasma averaged 81.7% for the column procedure and 40% for the organic extraction.
(7) This study was designed to investigate the localization and cyclic regulation of the mRNA for these two IGFBPs in the porcine ovary, RNA was extracted from whole ovaries morphologically classified as immature, preovulatory, and luteal.
(8) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(9) Among them, the coumarins, rutins, Centella asiatica extracts, procyanoside oligomers are the most prescribed.
(10) Average fluoroscopy time per procedure was 27.8 minutes of which 15.1 minutes were for nephrostomy tube insertion and 12.7 minutes were for calculi extraction.
(11) We have compared two new methods (a solvent extraction technique and a method involving a disposable, pre-packed reverse phase chromatography cartridge) with the standard method for determining the radiochemical purity of 99Tcm-HMPAO.
(12) To further characterize the molecular forms of GnRH in each species, the extracts were injected into a high pressure liquid chromatograph (HPLC).
(13) Nine of the in vivo synthesized early polypeptides can be precipitated specifically from infected cell extracts by antisera with specificity against early adenovirus proteins.
(14) After absorption of labeled glucose, two pools of trehalose are found in dormant spores, one of which is extractable without breaking the spores, and the other, only after the spores are disintegrated.
(15) Charcoal particles coated with the lipid extract were prepared and the suspension inoculated intravenously into mice.
(16) Long term follow up of extracapsular extraction showed visual results superior to those previously reported for intracapsular extraction.
(17) The ability of cytoplasmic extracts to induce DNA synthesis in isolated, quiescent nuclei.
(18) The antigenic composition of an extract of rat dust, as a source of aeroallergens for rat-sensitive individuals, has been investigated and compared to the antigenic composition of rat saliva and urine.
(19) Ether extracts were analyzed by gas chromatography-mass spectrometry (GC-MS) and various chlorinated and non-chlorinated compounds were detected, e.g.
(20) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.