(n.) The state of surpassing or going beyond limits; the being of a measure beyond sufficiency, necessity, or duty; that which exceeds what is usual or prover; immoderateness; superfluity; superabundance; extravagance; as, an excess of provisions or of light.
(n.) An undue indulgence of the appetite; transgression of proper moderation in natural gratifications; intemperance; dissipation.
(n.) The degree or amount by which one thing or number exceeds another; remainder; as, the difference between two numbers is the excess of one over the other.
Example Sentences:
(1) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(2) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(3) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(4) Excessive lip protrusion was eliminated, and arch leveled.
(5) Ten milliliters of the solution inappropriately came into contact with nasal mucous membranes, causing excessive drug absorption.
(6) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(7) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(8) Preliminary studies of different systems suggest several of them may have sensitivity to detect intraepithelial abnormalities in excess of 95%.
(9) Excessive accumulation of hydrogen ions in the brain may play a pivotal role in initiating the necrosis seen in infarction and following hyperglycemic augmentation of ischemic brain damage.
(10) Fifty-four cases were analysed, and a two-fold excess of clustering within one year was observed, both within single districts and between adjacent districts.
(11) The first one is a region with iodine insufficiency; the second one is a region where the people use table salt in excess.
(12) Addition of methacholine to the substance-P-treated cells caused a rapid increase in [3H]IP3, whereas a second addition of a 10-fold excess of substance P had no effect.
(13) It is possible that the marked elevations in obsessive-compulsive symptomatology and in interpersonal sensitivity may reflect in part a sensitization to excessive performance demands.
(14) Using the intersection point of these pH-logPCO2 lines as a point of equal hemoglobin-independent "base excess" for each condition, values for true base excess were plotted.
(15) This excess in diagnosis comprises, in particular, the ductal type, primarily its most aggressive forms.
(16) Attention is drawn to the desirability of differentiating between supra- and sub-gingival calculus in the CPITN scoring system and to the excessive treatment requirements that arise from classifying everyone with calculus as requiring prophylaxis and scaling.
(17) IgG-gold also adhered to M cells and excess unlabeled IgG inhibited IgA-gold binding; thus binding was not isotype-specific.
(18) The technique did not compromise cancer resection, excessively prolong operating time, or alter postoperative management.
(19) The temperature-activated 4 to 5 S EBP transformation is found to be highly reproducible without loss of [3H]estradiol-binding activity in a buffer containing an excess of [3H]estradiol, 40 mM Tris, 1 mM dithiothreitol, and 1 M urea at pH 7.4.
(20) The amount of cleavage products depends on the excess of H2O2 used.
Necessity
Definition:
(n.) The quality or state of being necessary, unavoidable, or absolutely requisite; inevitableness; indispensableness.
(n.) The condition of being needy or necessitous; pressing need; indigence; want.
(n.) That which is necessary; a necessary; a requisite; something indispensable; -- often in the plural.
(n.) That which makes an act or an event unavoidable; irresistible force; overruling power; compulsion, physical or moral; fate; fatality.
(n.) The negation of freedom in voluntary action; the subjection of all phenomena, whether material or spiritual, to inevitable causation; necessitarianism.
Example Sentences:
(1) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(2) Among 159 patients studied, the severity most frequent was Yahr stage 3 (63%) at first examination, indicating the necessity of earlier diagnosis.
(3) When a product is selected for a patient, consideration should be given to necessity, efficacy, adverse effects, and cost-effectiveness.
(4) Discussion deals with the plurality, specificity, variability, perceived necessity, sufficiency, international utility and career significance of British postgraduate qualifications.
(5) As a result of recent environmental changes in the health care industry, marketing has become a vital necessity for the survival of most hospitals.
(6) There is a necessity for early definitive decision-making in the borderline orthognathic surgery patient and the role of orthodontic camouflage is pointed out.
(7) For Kohut, interpretation depends on the prior establishment of a stable, sustaining transference; human connexion is a lifelong necessity and full understanding an achievable aim.
(8) Management and treatment issues are surveyed, such as the necessity to recognize that in some adolescents violence erupts not from narcissitic rage but from strong wishes for affectionate contact.
(9) A prospective study of the necessity of sedation, or analgesia, or both in total colonoscopy was performed.
(10) The authors report on the casuistry of aorto-coronary by-pass operations they performed between April 1971 and December 1974, discussing the criteria which indicate the necessity of operating, the principles of the operative techniques, and the results obtained.
(11) This case, despite the fatal outcome, emphasises the necessity for a comprehensive approach to the diagnosis of atypical pneumonia, including culture for Legionella, especially in immunocompromised patients.
(12) The sonographic method, with a 97.7% specificity and a negative predictive value of 89.5%, proved to be specific enough to eliminate the necessity of routine catheterization for measuring residual bladder volumes of greater than or equal to 150 cm3, thus decreasing the incidence of some major postoperative complications that can occur due to unnecessary catheterization.
(13) The development of gallstones following this procedure, however, has become more problematic in that further opeation becomes a real necessity.
(14) The necessity of using immunohistochemistry in the diagnosis of sinonasal tumours of fibromatous nature is emphasized.
(15) The experience with 1896 restorative operations on injured nerve trunks shows a necessity to consider the problems of diagnosis, prognosis and choice of the treatment, and especially the results of the nerve suture, not in all patients with nerve injury but only in separate groups being comparable with respect to the kind and severity of the trauma.
(16) Clinico-immunological studies on the use of drugs containing synthetic and biological polymers revealed their high immunomodulating activity and necessity of differentiated use of these drugs with relation to the pathogenetic mechanisms of development of bronchopulmonary diseases as well as mechanisms of their immunological action determined by the molecular mass of polymers as constituents of blood substitutes.
(17) We consider that the rarity of stricture rules out the necessity of any change in management, whether or not erosive oesophagitis is observed at endoscopy.
(18) The discrepancy between the judgement of the insurance company based upon the medical records and the patients complaints also 4-7 years after injury as well as the diversification of therapeutical procedures used in the long term patients career are indicating a necessity of prospective study on cervical spine injury.
(19) Through small and large acts of deprivation and destruction we follow the process: the removal of hope, of dignity, of luxury, of necessity, of self; the reduction of a man to a hoarder of grey slabs of bread and the scrapings of a soup bowl (wonderfully told all this, with a novelist's gift for detail and sometimes very nearly comic surprise), to the confinement of a narrow bed – in which there is "not even any room to be afraid" – with a stranger who doesn't speak your language, to the cruel illogicality of hating a fellow victim of oppression more than you hate the oppressor himself – one torment following another, and even the bleak comfort of thinking you might have touched rock bottom denied you as, when the most immediate cause of a particular stress comes to an end, "you are grievously amazed to see that another one lies behind; and in reality a whole series of others".
(20) In light of the AIDS epidemic and the necessity for safe-sex practices, the topic of caution and prevention is an emerging and critical discourse for the sexual encounter.