(a.) Characterized by, or exhibiting, excess; overmuch.
Example Sentences:
(1) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(2) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(3) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(4) Excessive lip protrusion was eliminated, and arch leveled.
(5) Ten milliliters of the solution inappropriately came into contact with nasal mucous membranes, causing excessive drug absorption.
(6) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(7) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(8) Preliminary studies of different systems suggest several of them may have sensitivity to detect intraepithelial abnormalities in excess of 95%.
(9) Excessive accumulation of hydrogen ions in the brain may play a pivotal role in initiating the necrosis seen in infarction and following hyperglycemic augmentation of ischemic brain damage.
(10) Fifty-four cases were analysed, and a two-fold excess of clustering within one year was observed, both within single districts and between adjacent districts.
(11) The first one is a region with iodine insufficiency; the second one is a region where the people use table salt in excess.
(12) Addition of methacholine to the substance-P-treated cells caused a rapid increase in [3H]IP3, whereas a second addition of a 10-fold excess of substance P had no effect.
(13) It is possible that the marked elevations in obsessive-compulsive symptomatology and in interpersonal sensitivity may reflect in part a sensitization to excessive performance demands.
(14) Using the intersection point of these pH-logPCO2 lines as a point of equal hemoglobin-independent "base excess" for each condition, values for true base excess were plotted.
(15) This excess in diagnosis comprises, in particular, the ductal type, primarily its most aggressive forms.
(16) Attention is drawn to the desirability of differentiating between supra- and sub-gingival calculus in the CPITN scoring system and to the excessive treatment requirements that arise from classifying everyone with calculus as requiring prophylaxis and scaling.
(17) IgG-gold also adhered to M cells and excess unlabeled IgG inhibited IgA-gold binding; thus binding was not isotype-specific.
(18) The technique did not compromise cancer resection, excessively prolong operating time, or alter postoperative management.
(19) The temperature-activated 4 to 5 S EBP transformation is found to be highly reproducible without loss of [3H]estradiol-binding activity in a buffer containing an excess of [3H]estradiol, 40 mM Tris, 1 mM dithiothreitol, and 1 M urea at pH 7.4.
(20) The amount of cleavage products depends on the excess of H2O2 used.
Moderate
Definition:
(a.) Kept within due bounds; observing reasonable limits; not excessive, extreme, violent, or rigorous; limited; restrained
(a.) Limited in quantity; sparing; temperate; frugal; as, moderate in eating or drinking; a moderate table.
(a.) Limited in degree of activity, energy, or excitement; reasonable; calm; slow; as, moderate language; moderate endeavors.
(a.) Not extreme in opinion, in partisanship, and the like; as, a moderate Calvinist.
(a.) Not violent or rigorous; temperate; mild; gentle; as, a moderate winter.
(a.) Limited as to degree of progress; as, to travel at moderate speed.
(a.) Limited as to the degree in which a quality, principle, or faculty appears; as, an infusion of moderate strength; a man of moderate abilities.
(a.) Limited in scope or effects; as, a reformation of a moderate kind.
(n.) One of a party in the Church of Scotland in the 18th century, and part of the 19th, professing moderation in matters of church government, in discipline, and in doctrine.
(v. t.) To restrain from excess of any kind; to reduce from a state of violence, intensity, or excess; to keep within bounds; to make temperate; to lessen; to allay; to repress; to temper; to qualify; as, to moderate rage, action, desires, etc.; to moderate heat or wind.
(v. t.) To preside over, direct, or regulate, as a public meeting; as, to moderate a synod.
(v. i.) To become less violent, severe, rigorous, or intense; as, the wind has moderated.
(v. i.) To preside as a moderator.
Example Sentences:
(1) The newborn with critical AS typically presents with severe cardiac failure and the infant with moderate failure, whereas children may be asymptomatic.
(2) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(3) In the surface epithelial cells, the basolateral cell surface showed moderate enzymatic activity.
(4) Histological studies showed that the resulting pancreatitis was usually mild to moderate, being severe only in association with sepsis.
(5) Systemic corticosteroids (i.e., prednisone, prednisolone or methylprednisolone) have improved the survival rate of patients with moderate and severe ulcerative colitis.
(6) We report the results of a double-blind, placebo-controlled trial of acitretin (Soriatane) in 15 patients with moderate to severe psoriasis.
(7) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
(8) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(9) Mild swallowing difficulties occurred in 18 patients (39%), moderate dysfunction in 23 (50%), and severe dysfunction in five (11%).
(10) The radius is estimated to be around 1.7 nm, which shows a moderate degree of hydration.
(11) The deep cerebellar nuclei were moderately labeled at birth and gradually decreased in density thereafter.
(12) The epithelium of Brunner's gland stained intensely with Ricinus communis agglutinin-I (RCA-I), succinylated-WGA (S-WGA) and wheat-germ agglutinin (WGA), moderately with Bandeirea simplicifolia agglutinin-I (BS-I), Concanavalia ensiformis agglutinin (Con A) peanut agglutinin (PNA) and Ulex europaeus agglutinin-I (UEA-I) and occasionally with Dolichos biflorus agglutinin (DBA), Lens culinaris agglutinin (LCA) and soybean agglutinin (SBA).
(13) 2-(4'-Isobutylphenyl)propionic acid, ibuprofen, is an antiinflammatory agent which possesses moderate platelet aggregation inhibitory activity.
(14) Electroretinographic (ERG), morphometric and biochemical studies on retinas from monkeys or rats reveal that moderate level developmental lead (Pb) exposure produces long-term selective rod deficits and degeneration.
(15) The remaining 33 sera (13.3 per cent) were classified as low, moderate or strong positives.
(16) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
(17) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(18) C. tropicalis was grown in a medium containing Brij 35, resulting in the induction of a moderate number of medium-sized peroxisomes.
(19) Data from 579 medical students from the classes of 1979-80 through 1983-84 attending a midwestern medical college were analyzed via moderated multiple regression.
(20) Altering the time of PMA exposure demonstrated that PMA inhibited chondrocyte phenotypic expression, rather than cell commitment: early (0-48 h) exposure to PMA (during chondrocytic commitment in vitro) had little inhibitory effect on the staining index, whereas, exposure from 49-96 h (presumably post-commitment) and 0-96 h had moderate and strong inhibitory effects, respectively, on cartilage synthesis.