(a.) Characterized by, or exhibiting, excess; overmuch.
Example Sentences:
(1) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(2) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(3) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(4) Excessive lip protrusion was eliminated, and arch leveled.
(5) Ten milliliters of the solution inappropriately came into contact with nasal mucous membranes, causing excessive drug absorption.
(6) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(7) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(8) Preliminary studies of different systems suggest several of them may have sensitivity to detect intraepithelial abnormalities in excess of 95%.
(9) Excessive accumulation of hydrogen ions in the brain may play a pivotal role in initiating the necrosis seen in infarction and following hyperglycemic augmentation of ischemic brain damage.
(10) Fifty-four cases were analysed, and a two-fold excess of clustering within one year was observed, both within single districts and between adjacent districts.
(11) The first one is a region with iodine insufficiency; the second one is a region where the people use table salt in excess.
(12) Addition of methacholine to the substance-P-treated cells caused a rapid increase in [3H]IP3, whereas a second addition of a 10-fold excess of substance P had no effect.
(13) It is possible that the marked elevations in obsessive-compulsive symptomatology and in interpersonal sensitivity may reflect in part a sensitization to excessive performance demands.
(14) Using the intersection point of these pH-logPCO2 lines as a point of equal hemoglobin-independent "base excess" for each condition, values for true base excess were plotted.
(15) This excess in diagnosis comprises, in particular, the ductal type, primarily its most aggressive forms.
(16) Attention is drawn to the desirability of differentiating between supra- and sub-gingival calculus in the CPITN scoring system and to the excessive treatment requirements that arise from classifying everyone with calculus as requiring prophylaxis and scaling.
(17) IgG-gold also adhered to M cells and excess unlabeled IgG inhibited IgA-gold binding; thus binding was not isotype-specific.
(18) The technique did not compromise cancer resection, excessively prolong operating time, or alter postoperative management.
(19) The temperature-activated 4 to 5 S EBP transformation is found to be highly reproducible without loss of [3H]estradiol-binding activity in a buffer containing an excess of [3H]estradiol, 40 mM Tris, 1 mM dithiothreitol, and 1 M urea at pH 7.4.
(20) The amount of cleavage products depends on the excess of H2O2 used.
Surfeit
Definition:
(n.) Excess in eating and drinking.
(n.) Fullness and oppression of the system, occasioned often by excessive eating and drinking.
(n.) Disgust caused by excess; satiety.
(v. i.) To load the stomach with food, so that sickness or uneasiness ensues; to eat to excess.
(v. i.) To indulge to satiety in any gratification.
(v. t.) To feed so as to oppress the stomach and derange the function of the system; to overfeed, and produce satiety, sickness, or uneasiness; -- often reflexive; as, to surfeit one's self with sweets.
(v. t.) To fill to satiety and disgust; to cloy; as, he surfeits us with compliments.
Example Sentences:
(1) I'm reminded of something Cooper said earlier, when talking about the pressures of this time of year for working parents, with its surfeit of plays and, "Oh God, not another school fair".
(2) This very tight clustering suggests a cis interaction between adjacent Surfeit genes.
(3) The clustered arrangement (no two adjacent genes are separated by more than 73 base pairs [bp] and two genes overlap by 133 bp at their 3' ends) of the four genes (Surf-1 to -4) identified so far in the mouse surfeit locus (T. Williams, J. Yon, C. Huxley, and M. Fried, Proc.
(4) The organization of the mouse surfeit locus is unusual in that it contains six housekeeping genes (Surf-1-Surf-6), which are unrelated by sequence homology, in the tightest mammalian gene cluster thus far described.
(5) When the faculty status of women and men academic anesthesiologists was examined a significant difference was found in rank distribution in age groups 40 to 44 (P less than 0.005) and 45 to 49 (P less than 0.001), where there was a deficit of professors and a surfeit of instructors among women.
(6) Here's Niall Mullen: "As a Liverpool fan who can barely buy his own groceries I am going to be outraged, outraged I tell you, if we fail to procure a player I've never heard of, who plays in a position in which we have a surfeit of players, for a club I've never seen play."
(7) We found no evidence of an initial surfeit of processing units, dendritic branches, or synapses.
(8) In this endocrine control, the renin axis provides the primary defence against sodium volume depletion and hypotension while atrial hormone plays an increasingly active counter-role for coping with situations that involve a sodium-volume surfeit or rising blood volume or blood pressure levels.
(9) Profound changes are occurring in the health care system, including a surfeit of physicians, cost containment, and competition.
(10) Using an interspecies backcross, we have mapped the HOX-5 and surfeit (surf) gene clusters within the proximal portion of mouse chromosome 2.
(11) In the adult, sodium surfeit is associated with an increase in urinary dopamine; the opposite occurs in the young.
(12) But we've had a surfeit of "behind the scenes" pictures of both coalition leaders; too many pictures of Cameron gurning at his new baby have led to this sort of material becoming a devalued currency.
(13) Responses to the energy surfeit led to intakes 104% and 116% of baseline, respectively.
(14) Since a repository would be expected to accumulate surplus material, one would predict that phosphorylase, which contains stoichio-metric amounts or pyridoxal phosphate, would increase in muscle of animals surfeited with the vitamin.
(15) What is called progress seems often to bring a surfeit of new experiences, facts, machines, noises, producing a feeling of helplessness, almost of despair.
(16) These data support the hypothesis that a surfeit of opioidergic ligand may potentiate drinking of alcoholic beverages.
(17) The concept of a basal level of body sodium (Strauss' state 'between surfeit and deficit') was studied by means of body sodium measurements in rats on different sodium intakes, in some cases after diuretic pretreatment.
(18) The invading fibers appear to encounter resistance at the basal lamina, but, once within the epithelium, at embryonic days 8-9, they form a surfeit of branches in columnar zones oriented radially toward the surface.
(19) Relative to their energy consumption on the medium-fat diet, the subjects spontaneously consumed an 11.3% deficit on the low-fat diet and a 15.4% surfeit on the high-fat diet (p less than 0.0001), resulting in significant changes in body weight (p less than 0.001).
(20) The mouse surfeit locus is unusual in that it contains a number of closely clustered genes (Surf-1, -2, and -4) that alternate in their direction of transcription (T. Williams, J. Yon, C. Huxley, and M. Fried, Proc.