(1) 5-Azacytidine (I) stability was increased approximately 10-fold over its stability in water or lactated Ringer injection by the addition of excess sodium bisulfite and the maintenance of pH approximately 2.5.
(2) Since the advance and return of sperm inside the tubes could facilitate the interaction of sperm with secretions participating in its maturation, the persistent infertility after vasectomy could be related to the contractile alteration that follows the excessive tubal distention.
(3) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(4) Excessive lip protrusion was eliminated, and arch leveled.
(5) Ten milliliters of the solution inappropriately came into contact with nasal mucous membranes, causing excessive drug absorption.
(6) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(7) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(8) Preliminary studies of different systems suggest several of them may have sensitivity to detect intraepithelial abnormalities in excess of 95%.
(9) Excessive accumulation of hydrogen ions in the brain may play a pivotal role in initiating the necrosis seen in infarction and following hyperglycemic augmentation of ischemic brain damage.
(10) Fifty-four cases were analysed, and a two-fold excess of clustering within one year was observed, both within single districts and between adjacent districts.
(11) The first one is a region with iodine insufficiency; the second one is a region where the people use table salt in excess.
(12) Addition of methacholine to the substance-P-treated cells caused a rapid increase in [3H]IP3, whereas a second addition of a 10-fold excess of substance P had no effect.
(13) It is possible that the marked elevations in obsessive-compulsive symptomatology and in interpersonal sensitivity may reflect in part a sensitization to excessive performance demands.
(14) Using the intersection point of these pH-logPCO2 lines as a point of equal hemoglobin-independent "base excess" for each condition, values for true base excess were plotted.
(15) This excess in diagnosis comprises, in particular, the ductal type, primarily its most aggressive forms.
(16) Attention is drawn to the desirability of differentiating between supra- and sub-gingival calculus in the CPITN scoring system and to the excessive treatment requirements that arise from classifying everyone with calculus as requiring prophylaxis and scaling.
(17) IgG-gold also adhered to M cells and excess unlabeled IgG inhibited IgA-gold binding; thus binding was not isotype-specific.
(18) The technique did not compromise cancer resection, excessively prolong operating time, or alter postoperative management.
(19) The temperature-activated 4 to 5 S EBP transformation is found to be highly reproducible without loss of [3H]estradiol-binding activity in a buffer containing an excess of [3H]estradiol, 40 mM Tris, 1 mM dithiothreitol, and 1 M urea at pH 7.4.
(20) The amount of cleavage products depends on the excess of H2O2 used.
Wild
Definition:
(superl.) Living in a state of nature; inhabiting natural haunts, as the forest or open field; not familiar with, or not easily approached by, man; not tamed or domesticated; as, a wild boar; a wild ox; a wild cat.
(superl.) Growing or produced without culture; growing or prepared without the aid and care of man; native; not cultivated; brought forth by unassisted nature or by animals not domesticated; as, wild parsnip, wild camomile, wild strawberry, wild honey.
(superl.) Desert; not inhabited or cultivated; as, wild land.
(superl.) Savage; uncivilized; not refined by culture; ferocious; rude; as, wild natives of Africa or America.
(superl.) Not submitted to restraint, training, or regulation; turbulent; tempestuous; violent; ungoverned; licentious; inordinate; disorderly; irregular; fanciful; imaginary; visionary; crazy.
(superl.) Exposed to the wind and sea; unsheltered; as, a wild roadstead.
(superl.) Indicating strong emotion, intense excitement, or /ewilderment; as, a wild look.
(superl.) Hard to steer; -- said of a vessel.
(n.) An uninhabited and uncultivated tract or region; a forest or desert; a wilderness; a waste; as, the wilds of America; the wilds of Africa.
(adv.) Wildly; as, to talk wild.
Example Sentences:
(1) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(2) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
(3) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(4) But when he speaks, the crowds who have come together to make a stand against government corruption and soaring fuel prices cheer wildly.
(5) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(6) One rat strain (TAS) is susceptible to the anticoagulant and lethal effects of warfarin and the other two strains are homozygous for warfarin resistance genes from either wild Welsh (HW) or Scottish (HS) rats.
(7) No reversions to wild-type levels were observed in 555 heterozygous offspring of crosses between homozygous Campines and normals.
(8) The kinetics of endocytosis and recycling of the wild-type and mutant receptors were compared.
(9) Genetic regulation of the ilvGMEDA cluster involves attenuation, internal promoters, internal Rho-dependent termination sites, a site of polarity in the ilvG pseudogene of the wild-type organism, and autoregulation by the ilvA gene product, the biosynthetic L-threonine deaminase.
(10) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(11) With one exception, the mutant control regions showed elevated beta-lactamase activity in comparison to the wild-type.
(12) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
(13) For example, stem pairing with a sequence other than wild-type resulted in normal protein binding in vitro but derepression of protein synthesis in vivo.
(14) Phage lysates of wild-type cells are capable of transducing auxotrophs of strain 78 to prototrophy at frequencies ranging from 0.3 x 10(-7) to 34 x 10(-7) per plaque-forming unit adsorbed.
(15) The mutant spores are pleomorphic and differ both in shape and size from the wild-type spores.
(16) Addition of streptomycin restores much of the wild-type behaviour.
(17) She read geography at Oxford, where Benazir Bhutto (a future prime minister of Pakistan, assassinated in 2007) introduced May to her future husband, Philip May: "I hate to say this, but it was at an Oxford University Conservative Association disco… this is wild stuff.
(18) A plasmid carrying this mutation, along with wild-type genes encoding the c and b subunits, was unusual in that it failed to complement a chromosomal c-subunit mutation on succinate minimal medium.
(19) Using allozymes as the genetic probe, data are presented which show that wild Drosophila buzzatii females and males engaged in copulation mate at random.
(20) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.